KEGG   Homo sapiens (human): 57657
Entry
57657             CDS       T01001                                 
Symbol
HCN3
Name
(RefSeq) hyperpolarization activated cyclic nucleotide gated potassium channel 3
  KO
K04956  hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04929  GnRH secretion
Drug target
Ivabradine (DG00246): D07165 D08095<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    57657 (HCN3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    57657 (HCN3)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Cyclic nucleotide-gated channel (HCN)
   57657 (HCN3)
SSDB
Motif
Pfam: Ion_trans Ion_trans_N cNMP_binding Ion_trans_2
Other DBs
NCBI-GeneID: 57657
NCBI-ProteinID: NP_065948
OMIM: 609973
HGNC: 19183
Ensembl: ENSG00000143630
UniProt: Q9P1Z3
Position
1:155277463..155289848
AA seq 774 aa
MEAEQRPAAGASEGATPGLEAVPPVAPPPATAASGPIPKSGPEPKRRHLGTLLQPTVNKF
SLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKE
ENSPPWIVFNVLSDTFFLLDLVLNFRTGIVVEEGAEILLAPRAIRTRYLRTWFLVDLISS
IPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHM
TYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSH
ALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQY
QEKYKQVEQYMSFHKLPADTRQRIHEYYEHRYQGKMFDEESILGELSEPLREEIINFTCR
GLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGA
RDTRLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVA
MDRLLRIGKKNSILQRKRSEPSPGSSGGIMEQHLVQHDRDMARGVRGRAPSTGAQLSGKP
VLWEPLVHAPLQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLVPV
RAGPWASTSRLPAPPARTLHASLSRAGRSQVSLLGPPPGGGGRRLGPRGRPLSASQPSLP
QRATGDGSPGRKGSGSERLPPSGLLAKPPRTAQPPRPPVPEPATPRGLQLSANM
NT seq 2325 nt   +upstreamnt  +downstreamnt
atggaggcagagcagcggccggcggcgggggccagcgaaggggcgacccctggactggag
gcggtgcctcccgttgctcccccgcctgcgaccgcggcctcaggtccgatccccaaatct
gggcctgagcctaagaggaggcaccttgggacgctgctccagcctacggtcaacaagttc
tcccttcgggtgttcggcagccacaaagcagtggaaatcgagcaggagcgggtgaagtca
gcgggggcctggatcatccacccctacagcgacttccggttttactgggacctgatcatg
ctgctgctgatggtggggaacctcatcgtcctgcctgtgggcatcaccttcttcaaggag
gagaactccccgccttggatcgtcttcaacgtattgtctgatactttcttcctactggat
ctggtgctcaacttccgaacgggcatcgtggtggaggagggtgctgagatcctgctggca
ccgcgggccatccgcacgcgctacctgcgcacctggttcctggttgacctcatctcttct
atccctgtggattacatcttcctagtggtggagctggagccacggttggacgctgaggtc
tacaaaacggcacgggccctacgcatcgttcgcttcaccaagatcctaagcctgctgagg
ctgctccgcctctcccgcctcatccgctacatacaccagtgggaggagatctttcacatg
acctatgacctggccagtgctgtggttcgcatcttcaacctcattgggatgatgctgctg
ctatgtcactgggatggctgtctgcagttcctggtgcccatgctgcaggacttccctccc
gactgctgggtctccatcaaccacatggtgaaccactcgtggggccgccagtattcccat
gccctgttcaaggccatgagccacatgctgtgcattggctatgggcagcaggcacctgta
ggcatgcccgacgtctggctcaccatgctcagcatgatcgtaggtgccacatgctacgcc
atgttcatcggccatgccacggcactcatccagtccctggactcttcccggcgtcagtac
caggagaagtacaagcaggtggagcagtacatgtccttccacaagctgccagcagacacg
cggcagcgcatccacgagtactatgagcaccgctaccagggcaagatgttcgatgaggaa
agcatcctgggcgagctgagcgagccgcttcgcgaggagatcattaacttcacctgtcgg
ggcctggtggcccacatgccgctgtttgcccatgccgaccccagcttcgtcactgcagtt
ctcaccaagctgcgctttgaggtcttccagccgggggatctcgtggtgcgtgagggctcc
gtggggaggaagatgtacttcatccagcatgggctgctcagtgtgctggcccgcggcgcc
cgggacacacgcctcaccgatggatcctactttggggagatctgcctgctaactaggggc
cggcgcacagccagtgttcgggctgacacctactgccgcctttactcactcagcgtggac
catttcaatgctgtgcttgaggagttccccatgatgcgccgggcctttgagactgtggcc
atggatcggctgctccgcatcggcaagaagaattccatactgcagcggaagcgctccgag
ccaagtccaggcagcagtggtggcatcatggagcagcacttggtgcaacatgacagagac
atggctcggggtgttcggggtcgggccccgagcacaggagctcagcttagtggaaagcca
gtactgtgggagccactggtacatgcgccccttcaggcagctgctgtgacctccaatgtg
gccattgccctgactcatcagcggggccctctgcccctctcccctgactctccagccacc
ctccttgctcgctctgcttggcgctcagcaggctctccagcttccccgctggtgcccgtc
cgagctggcccatgggcatccacctcccgcctgcccgccccacctgcccgaaccctgcac
gccagcctatcccgggcagggcgctcccaggtctccctgctgggtccccctccaggagga
ggtggacggcggctaggacctcggggccgcccactctcagcctcccaaccctctctgcct
cagcgggcaacaggcgatggctctcctgggcgtaagggatcaggaagtgagcggctgcct
ccctcagggctcctggccaaacctccaaggacagcccagccccccaggccaccagtgcct
gagccagccacaccccggggtctccagctttctgccaacatgtaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (15)   
DNA sequence (56)   
   RefSeq(nuc) (40)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (103)   

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