KEGG   Homo sapiens (human): 57787
Entry
57787             CDS       T01001                                 
Symbol
MARK4, MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D
Name
(RefSeq) microtubule affinity regulating kinase 4
  KO
K08798  MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    57787 (MARK4)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    57787 (MARK4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     57787 (MARK4)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   57787 (MARK4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     57787 (MARK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr KA1 UBA Kinase-like MELK_UBA Kdo ABC1 RIO1 UBA_2 Haspin_kinase
Other DBs
NCBI-GeneID: 57787
NCBI-ProteinID: NP_001186796
OMIM: 606495
HGNC: 13538
Ensembl: ENSG00000007047
UniProt: Q96L34
Structure
Position
19:45251271..45305284
AA seq 752 aa
MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQPHVGNYR
LLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVK
LFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHR
DLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIW
SLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCT
LEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEV
TATYLLLGRKTEEGGDRGAPGLALARVRAPSDTTNGTSSSKGTSHSKGQRSSSSTYHRQR
RHSDFCGPSPAPLHPKRSPTSTGEAELKEERLPGRKASCSTAGSGSRGLPPSSPMVSSAH
NPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGAERPSLLPNGKENSSGTPRVP
PASPSSHSLAPPSGERSRLARGSTIRSTFHGGQVRDRRAGGGGGGGVQNGPPASPTLAHE
AAPLPAGRPRPTTNLFTKLTSKLTRRVADEPERIGGPEVTSCHLPWDQTETAPRLLRFPW
SVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLP
RPGLRGVLFRRVAGTALAFRTLVTRISNDLEL
NT seq 2259 nt   +upstreamnt  +downstreamnt
atgtcttcgcggacggtgctggccccgggcaacgatcggaactcggacacgcatggcacc
ttgggcagtggccgctcctcggacaaaggcccgtcctggtccagccgctcactgggtgcc
cgttgccggaactccatcgcctcctgtcccgaggagcagccccacgtgggcaactaccgc
ctgctgaggaccattgggaagggcaactttgccaaagtcaagctggctcggcacatcctc
actggtcgggaggttgccatcaagattatcgacaaaacccagctgaatcccagcagcctg
cagaagctgttccgagaagtccgcatcatgaagggcctaaaccaccccaacatcgtgaag
ctctttgaggtgattgagactgagaagacgctgtacctggtgatggagtacgcaagtgct
ggagaagtgtttgactacctcgtgtcgcatggccgcatgaaggagaaggaagctcgagcc
aagttccgacagattgtttcggctgtgcactattgtcaccagaaaaatattgtacacagg
gacctgaaggctgagaacctcttgctggatgccgaggccaacatcaagattgctgacttt
ggcttcagcaacgagttcacgctgggatcgaagctggacacgttctgcgggagcccccca
tatgccgccccggagctgtttcagggcaagaagtacgacgggccggaggtggacatctgg
agcctgggagtcatcctgtacaccctcgtcagcggctccctgcccttcgacgggcacaac
ctcaaggagctgcgggagcgagtactcagagggaagtaccgggtccctttctacatgtca
acagactgtgagagcatcctgcggagatttttggtgctgaacccagctaaacgctgtact
ctcgagcaaatcatgaaagacaaatggatcaacatcggctatgagggtgaggagttgaag
ccatacacagagcccgaggaggacttcggggacaccaagagaattgaggtgatggtgggt
atgggctacacacgggaagaaatcaaagagtccttgaccagccagaagtacaacgaagtg
accgccacctacctcctgctgggcaggaagactgaggagggtggggaccggggcgcccca
gggctggccctggcacgggtgcgggcgcccagcgacaccaccaacggaacaagttccagc
aaaggcaccagccacagcaaagggcagcggagttcctcttccacctaccaccgccagcgc
aggcatagcgatttctgtggcccatcccctgcacccctgcaccccaaacgcagcccgacg
agcacgggggaggcggagctgaaggaggagcggctgccaggccggaaggcgagctgcagc
accgcggggagtgggagtcgagggctgcccccctccagccccatggtcagcagcgcccac
aaccccaacaaggcagagatcccagagcggcggaaggacagcacgagcacccccaacaac
ctccctcctagcatgatgacccgcagaaacacctacgtttgcacagaacgcccgggggct
gagcgcccgtcactgttgccaaatgggaaagaaaacagctcaggcaccccacgggtgccc
cctgcctccccctccagtcacagcctggcacccccatcaggggagcggagccgcctggca
cgtggttccaccatccgcagcaccttccatggtggccaggtccgggaccggcgggcaggg
ggtgggggtggtgggggtgtgcagaatgggccccctgcctctcccacactggcccatgag
gctgcacccctgcccgccgggcggccccgccccaccaccaacctcttcaccaagctgacc
tccaaactgacccgaagggtcgcagacgaacctgagagaatcgggggacctgaggtcaca
agttgccatctaccttgggatcaaacggaaaccgccccccggctgctccgattcccctgg
agtgtgaagctgaccagctcgcgccctcctgaggccctgatggcagctctgcgccaggcc
acagcagccgcccgctgccgctgccgccagccacagccgttcctgctggcctgcctgcac
gggggtgcgggcgggcccgagcccctgtcccacttcgaagtggaggtctgccagctgccc
cggccaggcttgcggggagttctcttccgccgtgtggcgggcaccgccctggccttccgc
accctcgtcacccgcatctccaacgacctcgagctctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (11)   
   Pfam (11)   
All databases (84)   

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