KEGG   Homo sapiens (human): 5795
Entry
5795              CDS       T01001                                 
Symbol
PTPRJ, CD148, DEP1, HPTP_eta, HPTPeta, R-PTP-ETA, R-PTP-J, SCC1, THC10
Name
(RefSeq) protein tyrosine phosphatase receptor type J
  KO
K05698  receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04520  Adherens junction
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06223  TNF signaling (cancer)
  Element
N01411  Metals to NFKB signaling pathway
Disease
H00978  Thrombocytopenia (THC)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    5795 (PTPRJ)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    5795 (PTPRJ)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5795 (PTPRJ)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    5795 (PTPRJ)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     5795 (PTPRJ)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Receptor PTPs
    5795 (PTPRJ)
CD molecules [BR:hsa04090]
 Proteins
  5795 (PTPRJ)
SSDB
Motif
Pfam: Y_phosphatase fn3 PTP_tm Pur_ac_phosph_N PTPlike_phytase DSPc Interfer-bind Y_phosphatase3 GH97_C
Other DBs
NCBI-GeneID: 5795
NCBI-ProteinID: NP_002834
OMIM: 600925
HGNC: 9673
Ensembl: ENSG00000149177
UniProt: Q12913 Q9NPR5
Structure
Position
11:47980559..48170839
AA seq 1337 aa
MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILCAGGTPSPIPDPSVATVATGENGITQ
ISSTAESFHKQNGTGTPQVETNTSEDGESSGANDSLRTPEQGSNGTDGASQKTPSSTGPS
PVFDIKAVSISPTNVILTWKSNDTAASEYKYVVKHKMENEKTITVVHQPWCNITGLRPAT
SYVFSITPGIGNETWGDPRVIKVITEPIPVSDLRVALTGVRKAALSWSNGNGTASCRVLL
ESIGSHEELTQDSRLQVNISGLKPGVQYNINPYLLQSNKTKGDPLGTEGGLDASNTERSR
AGSPTAPVHDESLVGPVDPSSGQQSRDTEVLLVGLEPGTRYNATVYSQAANGTEGQPQAI
EFRTNAIQVFDVTAVNISATSLTLIWKVSDNESSSNYTYKIHVAGETDSSNLNVSEPRAV
IPGLRSSTFYNITVCPVLGDIEGTPGFLQVHTPPVPVSDFRVTVVSTTEIGLAWSSHDAE
SFQMHITQEGAGNSRVEITTNQSIIIGGLFPGTKYCFEIVPKGPNGTEGASRTVCNRTVP
SAVFDIHVVYVTTTEMWLDWKSPDGASEYVYHLVIESKHGSNHTSTYDKAITLQGLIPGT
LYNITISPEVDHVWGDPNSTAQYTRPSNVSNIDVSTNTTAATLSWQNFDDASPTYSYCLL
IEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLEPGRKSFCTDPA
SMASFDCEVVPKEPALVLKWTCPPGANAGFELEVSSGAWNNATHLESCSSENGTEYRTEV
TYLNFSTSYNISITTVSCGKMAAPTRNTCTTGITDPPPPDGSPNITSVSHNSVKVKFSGF
EASHGPIKAYAVILTTGEAGHPSADVLKYTYEDFKKGASDTYVTYLIRTEEKGRSQSLSE
VLKYEIDVGNESTTLGYYNGKLEPLGSYRACVAGFTNITFHPQNKGLIDGAESYVSFSRY
SDAVSLPQDPGVICGAVFGCIFGALVIVTVGGFIFWRKKRKDAKNNEVSFSQIKPKKSKL
IRVENFEAYFKKQQADSNCGFAEEYEDLKLVGISQPKYAAELAENRGKNRYNNVLPYDIS
RVKLSVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTK
CVEQGRTKCEEYWPSKQAQDYGDITVAMTSEIVLPEWTIRDFTVKNIQTSESHPLRQFHF
TSWPDHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIE
NENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVRSQKDSKVDLIYQNTTAMTIY
ENLAPVTTFGKTNGYIA
NT seq 4014 nt   +upstreamnt  +downstreamnt
atgaagccggcggcgcgggaggcgcggctgcctccgcgctcgcccgggctgcgctgggcg
ctgccgctgctgctgctgctgctgcgcctgggccagatcctgtgcgcaggtggcacccct
agtccaattcctgacccttcagtagcaactgttgccacaggggaaaatggcataacgcag
atcagcagtacagcagaatcctttcataaacagaatggaactggaacacctcaggtggaa
acaaacaccagtgaggatggtgaaagctctggagccaacgatagtttaagaacacctgaa
caaggatctaatgggactgatggggcatctcaaaaaactcccagtagcactgggcccagt
cctgtgtttgacattaaagctgtttccatcagtccaaccaatgtgatcttaacttggaaa
agtaatgacacagctgcttctgagtacaagtatgtagtaaagcataagatggaaaatgag
aagacaattactgttgtgcatcaaccatggtgtaacatcacaggcttacgtccagcgact
tcatatgtattctccatcactccaggaataggcaatgagacttggggagatcccagagtc
ataaaagtcatcacagagccgatcccagtttctgatctccgtgttgccctcacgggtgtg
aggaaggctgctctctcctggagcaatggcaatggcactgcctcctgccgggttcttctt
gaaagcattggaagccatgaggagttgactcaagactcaagacttcaggtcaatatctcg
ggcctgaagccaggggttcaatacaacatcaacccgtatcttctacaatcaaataagaca
aagggagaccccttgggcacagaaggtggcttggatgccagcaatacagagagaagccgg
gcagggagccccaccgcccctgtgcatgatgagtccctcgtgggacctgtggacccatcc
tccggccagcagtcccgagacacggaagtcctgcttgtcgggttagagcctggcacccga
tacaatgccaccgtttattcccaagcagcgaatggcacagaaggacagccccaggccata
gagttcaggacaaatgctattcaggtttttgacgtcaccgctgtgaacatcagtgccaca
agcctgaccctgatctggaaagtcagcgataacgagtcgtcatctaactatacctacaag
atacatgtggcgggggagacagattcttccaatctcaacgtcagtgagcctcgcgctgtc
atccccggactccgctccagcaccttctacaacatcacagtgtgtcctgtcctaggtgac
atcgagggcacgccgggcttcctccaagtgcacaccccccctgttccagtttctgacttc
cgagtgacagtggtcagcacgacggagatcggcttagcatggagcagccatgatgcagaa
tcatttcagatgcatatcacacaggagggagctggcaattctcgggtagaaataaccacc
aaccaaagtattatcattggtggcttgttccctggaaccaagtattgctttgaaatagtt
ccaaaaggaccaaatgggactgaaggggcatctcggacagtttgcaatagaactgttccc
agtgcagtgtttgacatccacgtggtctacgtcaccaccacggagatgtggctggactgg
aagagccctgacggtgcttccgagtatgtctaccatttagtcatagagtccaagcatggc
tctaaccacacaagcacgtatgacaaagcgattactctccagggcctgattccgggcacc
ttatataacatcaccatctctccagaagtggaccacgtctggggggaccccaactccact
gcacagtacacacggcccagcaatgtgtccaacattgatgtaagtaccaacaccacagca
gcaactttaagttggcagaactttgatgacgcctctcccacgtactcctactgccttctt
attgagaaggctggaaattccagcaacgcaacacaagtagtcacggacattggaattact
gacgctacagtcactgaattaatacctggctcatcatacacagtggagatctttgcacaa
gtaggggatgggatcaagtcactggaacctggccggaagtcattctgtacagatcctgcg
tccatggcctccttcgactgcgaagtggtccccaaagagccagccctggttctcaaatgg
acctgccctcctggcgccaatgcaggctttgagctggaggtcagcagtggagcctggaac
aatgcgacccacctggagagctgctcctctgagaatggcactgagtatagaacggaagtc
acgtatttgaatttttctacctcgtacaacatcagcatcaccactgtgtcctgtggaaag
atggcagcccccacccggaacacctgcactactggcatcacagatccccctcctccagat
ggatcccctaatattacatctgtcagtcacaattcagtaaaggtcaagttcagtggattt
gaagccagccacggacccatcaaagcctatgctgtcattctcaccaccggggaagctggt
cacccttctgcagatgtcctgaaatacacgtatgaggatttcaaaaagggagcctcagat
acttatgtgacatacctcataagaacagaagaaaagggacgttctcagagcttgtctgaa
gttttgaaatatgaaattgacgttgggaatgagtcaaccacacttggttattacaatggg
aagctggaacctctgggctcctaccgggcttgtgtggctggcttcaccaacattaccttc
caccctcaaaacaaggggctcattgatggggctgagagctatgtgtccttcagtcgctac
tcagatgctgtttccttgccccaggatccaggtgtcatctgtggagcggtttttggctgt
atctttggtgccctggttattgtgactgtgggaggcttcatcttctggagaaagaagagg
aaagatgcaaagaataatgaagtgtccttttctcaaattaaacctaaaaaatctaagtta
atcagagtggagaattttgaggcctacttcaagaagcagcaagctgactccaactgtggg
ttcgcagaggaatacgaagatctgaagcttgttggaattagtcaacctaaatatgcagca
gaactggctgagaatagaggaaagaatcgctataataatgttctgccctatgatatttcc
cgtgtcaaactttcggtccagacccattcaacggatgactacatcaatgccaactacatg
cctggctaccactccaagaaagattttattgccacacaaggacctttaccgaacactttg
aaagatttttggcgtatggtttgggagaaaaatgtatatgccatcattatgttgactaaa
tgtgttgaacagggaagaaccaaatgtgaggagtattggccctccaagcaggctcaggac
tatggagacataactgtggcaatgacatcagaaattgttcttccggaatggaccatcaga
gatttcacagtgaaaaatatccagacaagtgagagtcaccctctgagacagttccatttc
acctcctggccagaccacggtgttcccgacaccactgacctgctcatcaacttccggtac
ctcgttcgtgactacatgaagcagagtcctcccgaatcgccgattctggtgcattgcagt
gctggggtcggaaggacgggcactttcattgccattgatcgtctcatctaccagatagag
aatgagaacaccgtggatgtgtatgggattgtgtatgaccttcgaatgcataggccttta
atggtgcagacagaggaccagtatgttttcctcaatcagtgtgttttggatattgtcaga
tcccagaaagactcaaaagtagatcttatctaccagaacacaactgcaatgacaatctat
gaaaaccttgcgcccgtgaccacatttggaaagaccaatggttacatcgcctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (24)   
   RefSeq(nuc) (6)   
   GenBank (9)   
   EMBL (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (9)   
   Pfam (9)   
All databases (91)   

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