KEGG   Homo sapiens (human): 5810
Entry
5810              CDS       T01001                                 
Symbol
RAD1, HRAD1, REC1
Name
(RefSeq) RAD1 checkpoint DNA exonuclease
  KO
K02830  cell cycle checkpoint protein [EC:3.1.11.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04218  Cellular senescence
Network
nt06506  Double-strand break repair
  Element
N01451  ATR signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    5810 (RAD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5810 (RAD1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     5810 (RAD1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Rad9-Hus1-Rad1 complex
    5810 (RAD1)
   Rad17-Mec3-Ddc1 complex
    5810 (RAD1)
SSDB
Motif
Pfam: Rad1 Pro_3_hydrox_C
Other DBs
NCBI-GeneID: 5810
NCBI-ProteinID: NP_002844
OMIM: 603153
HGNC: 9806
Ensembl: ENSG00000113456
UniProt: O60671
Structure
Position
5:complement(34905260..34915504)
AA seq 282 aa
MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQ
ANAFIQAGIFQEFKVQEESVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLM
LFLEEGGVVTVCKINTQEPEETLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQIT
MSPDKPYFRLSTFGNAGSSHLDYPKDSDLMEAFHCNQTQVNRYKISLLKPSTKALVLSCK
VSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPESES
NT seq 849 nt   +upstreamnt  +downstreamnt
atgccccttctgacccaacagatccaagacgaggatgatcagtacagccttgtggccagc
cttgacaacgttaggaatctctccactatcttgaaagctattcatttccgagaacatgcc
acgtgtttcgcaactaaaaatggtatcaaagtaacagtggaaaatgcaaagtgtgtgcaa
gcaaatgcttttattcaggctggaatatttcaggagtttaaagttcaggaagagtctgtt
acttttcgaattaatttaactgtccttttagactgtttatctatttttggatcaagtcct
atgccagggactttaactgcacttcgaatgtgttaccaaggttatggttaccctttgatg
ctgttcctggaagaaggaggagtggtgacagtctgcaaaatcaatacacaggaacctgag
gagaccctggactttgatttctgcagcaccaatgttattaataaaattattctgcagtca
gaggggctccgtgaagcattttctgaattggatatgacgagtgaagtcctacaaattacc
atgtctcctgacaagccttatttcaggttatctacttttggaaatgcaggaagttcccac
cttgactatcccaaagattctgatttgatggaagcatttcattgtaatcagacccaagtc
aacagatacaagatttccttactgaaaccctctacaaaggcattagtcctatcttgtaag
gtatctattcggacagataacagaggcttcctttcattacagtatatgattagaaatgaa
gatggacaaatatgttttgtggaatattactgctgccctgatgaagaagttcctgaatct
gagtcttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (13)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (44)   
   RefSeq(nuc) (6)   
   GenBank (19)   
   EMBL (19)   
3D Structure (6)   
   PDB (6)   
Protein domain (2)   
   Pfam (2)   
All databases (86)   

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