KEGG   Homo sapiens (human): 5885
Entry
5885              CDS       T01001                                 
Symbol
RAD21, CDLS4, HR21, HRAD21, MCD1, MGS, NXP1, SCC1, hHR21
Name
(RefSeq) RAD21 cohesin complex component
  KO
K06670  cohesin complex subunit SCC1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06512  Chromosome cohesion and segregation
  Element
N01482  Cohesin loading
N01486  Cohesin dissociation in anaphase
Disease
H00631  Cornelia de Lange syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    5885 (RAD21)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    5885 (RAD21)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Cohesin complex
    5885 (RAD21)
SSDB
Motif
Pfam: Rad21_Rec8_N Rad21_Rec8 SMC_ScpA RPA43_OB CDC45
Other DBs
NCBI-GeneID: 5885
NCBI-ProteinID: NP_006256
OMIM: 606462
HGNC: 9811
Ensembl: ENSG00000164754
UniProt: O60216
Structure
Position
8:complement(116845934..116874776)
AA seq 631 aa
MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLL
LGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQP
LPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDD
DMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGG
IFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNE
EEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKL
MMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF
ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKA
GQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE
DEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSF
LVLKKQQAIELTQEEPYSDIIATPGPRFHII
NT seq 1896 nt   +upstreamnt  +downstreamnt
atgttctacgcacattttgttctcagtaaaagagggcctctggccaaaatttggctagcg
gcccattgggataagaagctaaccaaagcccatgtgttcgagtgtaatttagagagcagc
gtggagagtatcatctcaccaaaggtgaaaatggcattacggacatcaggacatctctta
ctgggagtagttcgaatctatcacaggaaagccaaataccttcttgcagactgtaatgaa
gcattcattaagataaagatggcttttcggccaggtgtggttgacctgcctgaggaaaat
cgggaagcagcttataatgccattactttacctgaagaatttcatgactttgatcagcca
ctgcctgacttagatgacatcgatgtggcccagcagttcagcttgaatcagagtagagtg
gaagagataaccatgagagaagaagttgggaacatcagtattttacaagaaaatgatttt
ggtgattttggaatggatgatcgtgagataatgagagaaggcagtgcttttgaggatgac
gacatgttagtaagcactactacttctaacctcctattagagtctgaacagagcaccagc
aatctgaatgagaaaattaaccatttagaatatgaagatcaatataaggatgataatttt
ggagaaggaaatgatggtggaatattagatgacaaacttattagtaataatgatggcggt
atctttgatgatccccctgccctctctgaggcaggggtgatgttgccagagcagcctgca
catgacgatatggatgaggatgataatgtatcaatgggtgggcctgatagtcctgattca
gtggatcccgttgaaccaatgccaaccatgactgatcaaacaacacttgttccaaatgag
gaagaagcatttgcattggagcctattgatataactgttaaagaaacaaaagccaagagg
aagaggaagctaattgttgacagtgtcaaagagttggatagcaagacaattagagcccaa
cttagtgattattcagatattgttactactttggatctggcaccgcccaccaagaaattg
atgatgtggaaagagacaggaggagtagaaaaactgttttctttacctgctcagcctttg
tggaataacagactactgaagctctttacacgctgtcttacaccgcttgtaccagaagac
cttagaaaaaggaggaaaggaggagaggcagataatttggatgaattcctcaaagaattt
gaaaatccagaggttcctagagaggaccagcaacagcagcatcagcagcgtgatgttatc
gatgagcccattattgaagagccaagccgcctccaggagtcagtgatggaggccagcaga
acaaacatagatgagtcagctatgcctccaccaccacctcagggagttaagcgaaaagct
ggacaaattgacccagagcctgtgatgcctcctcagcaggtagagcagatggaaatacca
cctgtagagcttcccccagaagaacctccaaatatctgtcagctaataccagagttagaa
cttctgccagaaaaagagaaggagaaagagaaggaaaaagaagatgatgaagaggaagag
gatgaagatgcatcagggggcgatcaagatcaggaagaaagaagatggaacaaaaggact
cagcagatgcttcatggtcttcagcgtgctcttgctaaaactggagctgaatctatcagt
ttgcttgagttatgtcgaaatacgaacagaaaacaagctgccgcaaagttctacagcttc
ttggttcttaaaaagcagcaagctattgagctgacacaggaagaaccgtacagtgacatc
atcgcaacacctggaccaaggttccatattatataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (10)   
   PDB (10)   
Protein domain (5)   
   Pfam (5)   
All databases (72)   

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