KEGG   Homo sapiens (human): 6002
Entry
6002              CDS       T01001                                 
Symbol
RGS12
Name
(RefSeq) regulator of G protein signaling 12
  KO
K16449  regulator of G-protein signaling
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09193 Unclassified: signaling and cellular processes
   99995 Signaling proteins
    6002 (RGS12)
SSDB
Motif
Pfam: RGS12_usC RGS12_us1 RGS12_us2 RGS RBD PDZ GoLoco PDZ_6 PID PDZ_2 TUG-UBL1 PT-HINT
Other DBs
NCBI-GeneID: 6002
NCBI-ProteinID: NP_937872
OMIM: 602512
HGNC: 9994
Ensembl: ENSG00000159788
UniProt: O14924
Structure
Position
4:3285891..3439913
AA seq 1447 aa
MFRAGEASKRPLPGPSPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA
GDQILAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGVGRFESCSSDEEGGLYEGKGWL
KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASNSEPLKLKQRSLSESAATRFD
VGHESINNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL
PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA
FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG
FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS
NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGAQPWGAPWTGPFCPDP
EGSPPFEAAHQTDRFWDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGAGCGFNQRWLPV
HVLREWQCGHTSDQDSYTDSTDGWSSINCGTLPPPMSKIPADRYRVEGSFAQPPLNAPKR
EWSRKAFGMQSIFGPHRNVRKTKEDKKGSKFGRGTGLTQPSQRTSARRSFGRSKRFSITR
SLDDLESATVSDGELTGADLKDCVSNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL
QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT
PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA
LPDSQQVPSSPASKHSLGSDHSSVSTPKKLSGKSKSGRSLNEELGDEDSEKKRKGAFFSW
SRTRSTGRSQKKREHGDHADDALHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA
TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS
ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVARYGLDLSGLLVRLSG
EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASADKQKGVPVKQNTAVNSSSRNHSATGEE
RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN
RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTPAAVAKGFSKRSATGNGRESASQPGEQ
WEPVQESSDSPSTSPGSASSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTAQIWKRQ
SQEVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSTPQEVPGPSRPGSGTHGSRD
LPVNRIIDVDLVTGSAPGRDGGIAGAQAGPGRSQASGGPPTSDLPGLGPVPGEPAKPKTS
AHHATFV
NT seq 4344 nt   +upstreamnt  +downstreamnt
atgtttagagctggggaggcctccaaacgcccattgcctgggccgtcgcccccaagggtg
cggagtgtggaggttgcccgggggagggccggctacggattcacgctttcgggacaggca
ccctgtgtgctcagctgcgtcatgagagggagccctgcggatttcgtgggcctccgagct
ggagaccagatacttgctgtcaatgaaatcaacgtgaaaaaagcatctcatgaagatgta
gtgaaattaattgggaagtgctctggtgtccttcacatggtgattgctgaaggcgtcggc
cgcttcgaatcctgttccagtgatgaagaagggggactctatgaaggaaaaggctggctg
aagcccaagctggattctaaagcactaggtataaacagagcagagcgagtcgtggaggaa
atgcagtctggtggaattttcaatatgatttttgaaaacccgagcctttgtgcgagcaat
tcagagcccttgaaattgaaacaaagatccctttcagagtcggccgcaactcgatttgat
gttggacatgaaagtataaataatccaaatcccaacatgctttctaaggaggaaatatca
aaagttattcatgatgattcggttttcagcattggactagaaagtcatgacgattttgca
ttggatgcaagtattttaaacgtggcgatgatcgtgggctacttaggctccattgagctt
ccttccacgagctccaacctggagtccgacagcttgcaagccatccgcggctgcatgcgg
cgcctgcgggcagagcagaaaatccactcgctggtgaccatgaagatcatgcacgactgt
gtgcagctgagcactgacaaggctggagtcgtggccgagtacccggccgagaagctggcc
ttcagcgccgtgtgcccggacgaccggcgatttttcgggttggttaccatgcagacgaat
gacgacgggagcctggcccaggaggaggagggcgccctgcggacttcctgccacgtgttc
atggtggacccagacttgtttaatcacaagatccaccaaggcattgctcggcggtttggg
tttgagtgcacggccgacccagacaccaatggctgtctggaattcccggcgtcctccctc
cccgtcctgcagttcatctctgtcctgtaccgagacatgggtgagctgattgagggcatg
cgggcccgcgcctttctggacggggacgccgatgcccaccagaacaacagcaccagcagc
aacagtgacagcggcattgggaacttccaccaggaggagaagagcaaccgggtccttgtg
gtggacctgggtgggagctcgagcagacacggccccggaggcagcgcgtgggacggtgtg
ggtgggaggggtgcccagccctggggtgctccctggactgggcccttctgtccggacccc
gaagggagccccccatttgaggccgctcatcagactgacaggttctgggacctaaacaag
cacctagggccagcctctcctgtggaggtgcccccagcttccttgaggagctcagtcccc
ccttccaagaggggcaccgtgggtgctggctgtggtttcaaccagcgctggctcccggtc
cacgtgctccgggagtggcagtgcggacacaccagcgaccaggactcttacacagattcc
accgatggctggtccagcatcaactgcggcacactgccccctcctatgagcaagatcccc
gcagaccgctacagggtggagggcagcttcgcgcagcccccgctgaatgccccgaagagg
gagtggtccaggaaggcctttggaatgcaaagcatttttggtccccatcgaaatgttcga
aagactaaggaagataaaaagggctcaaaatttgggcggggaactggactcactcagcct
tctcaacgcacgtctgctcggagatcatttgggagatccaagagattcagtatcactcgc
tcccttgatgatcttgagtctgcaactgtgtctgatggcgagttgacgggcgccgacctg
aaggactgcgtcagcaacaacagcctgagcagcaatgccagcctccccagcgtgcagagc
tgccggcgcctgcgtgagaggagggtcgccagctgggccgtgtcctttgagcgcctgctg
caggaccccgtcggtgtccgctacttctctgattttctaaggaaagaattcagtgaagaa
aacattttattctggcaggcctgtgaatattttaatcatgttcctgcacatgacaaaaag
gagctttcctacagggcccgggagattttcagtaagtttctctgcagcaaagccaccacc
ccggtcaacatcgacagccaggcccagctagcagacgacgtcctccgcgcacctcaccca
gacatgttcaaggagcagcagctgcagatcttcaatctcatgaagtttgatagctacact
cgctttctgaagtccccgctgtaccaggaatgcatcctggcggaagtggagggccgtgca
ctcccggactcgcagcaggtccccagcagcccggcttccaagcacagcctcggttcagac
cactccagtgtgtccacgccaaaaaagttaagtggaaaatcaaaatccggccgatccctg
aatgaagagctgggggatgaggacagcgagaagaagcggaaaggcgcgtttttctcgtgg
tcgcggaccaggagcaccgggaggtcccagaaaaagagggagcacggggaccacgcagac
gacgccctgcatgccaatggaggcctgtgtcgccgagagtcgcagggctctgtgtcctct
gcggggagcctggacctgtcggaggcctgcaggactttggcacccgagaaggacaaggcc
accaagcactgctgcattcatctcccggatgggacatcctgcgtggtggctgtcaaggcg
ggcttctccatcaaagacatcctgtccggactctgtgagcggcatggcatcaacggggcg
gccgcggacctcttcctggtgggcggggacaagcctctggtgctgcaccaagacagtagc
atcttggagtcaagggacctgcgcctagaaaagcgcaccttgtttcggctggatcttgtt
ccgattaaccggtcagtgggactcaaggccaagcccaccaagcccgtcacggaggtgctg
cggcccgtggtggccagatacggcctggacctcagtggcctgctggtgaggctgagtgga
gagaaggagcccctggaccttggcgcccctatatcgagtctggacggacagcgggttgtc
ttggaggagaaggatccttccagaggaaaggcatccgcagataaacagaaaggtgtgcca
gtgaaacagaacacagctgtaaattccagctccagaaaccactcggctacgggagaggaa
agaacactaggcaagtctaattctattaaaataaaaggagaaaatggaaaaaatgctagg
gatccccggctttcaaagagagaagaatctattgcaaagattgggaaaaaaaaatatcag
aaaattaatttggacgaagcagaggagttttttgagcttatttccaaagctcagagcaac
agagcagatgaccaacgtgggctgctaaggaaggaagacctggtgttgccagagttcctc
cgtttacctcctggttccacagaactcaccctccccactccagctgctgtggccaagggc
tttagcaagagaagcgccacaggcaacggccgggagagcgcctcccagcctggcgagcag
tgggagccagtccaggagagcagcgacagcccgtccaccagcccgggctcagcctccagc
ccccctggacctcctgggacgaccccccccgggcagaagtctcccagcgggcccttctgc
actccccagtcccccgtctccctcgcgcaggagggcaccgcccagatctggaagaggcag
tctcaggaagtggaggccgggggcatccagacggtggaggatgagcacgtggccgagctg
accctgatgggggagggggacatcagcagccccaacagcaccttgctgccgccgccctcc
accccccaggaagtgccaggaccttccagaccaggaagtgggacccatggcagccgagac
ctcccagtcaacagaatcatcgatgtggatcttgtaactggctcggcgcccgggcgggat
ggtggcatagcgggggcacaggctggccctgggaggtcgcaggccagtggtgggcctcct
acatcagacctccctggcttgggccccgtcccgggtgagcctgctaagcccaagaccagc
gctcaccacgccaccttcgtctga

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Ontology (1)   
   KEGG BRITE (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (30)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (28)   
DNA sequence (88)   
   RefSeq(nuc) (32)   
   GenBank (28)   
   EMBL (28)   
3D Structure (2)   
   PDB (2)   
Protein domain (12)   
   Pfam (12)   
All databases (174)   

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