KEGG   Homo sapiens (human): 64798
Entry
64798             CDS       T01001                                 
Symbol
DEPTOR, DEP.6, DEPDC6, hDEPTOR
Name
(RefSeq) DEP domain containing MTOR interacting protein
  KO
K20402  DEP domain-containing mTOR-interacting protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04150  mTOR signaling pathway
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461  Huntington disease
nt06462  Spinocerebellar ataxia
nt06466  Pathways of neurodegeneration
nt06522  mTOR signaling
nt06532  Autophagy
  Element
N00155  Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N01575  TSC1/2-mTORC1 signaling pathway
N01578  GATOR1-mTORC1 signaling pathway
N01584  FLCN-mTORC1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    64798 (DEPTOR)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    64798 (DEPTOR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    64798 (DEPTOR)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    64798 (DEPTOR)
   mTORC2 complex
    64798 (DEPTOR)
SSDB
Motif
Pfam: DEP PDZ_6 GPAT_C PDZ
Other DBs
NCBI-GeneID: 64798
NCBI-ProteinID: NP_073620
OMIM: 612974
HGNC: 22953
Ensembl: ENSG00000155792
UniProt: Q8TB45
Structure
Position
8:119873722..120050918
AA seq 409 aa
MEEGGSTGSAGSDSSTSGSGGAQQRELERMAEVLVTGEQLRLRLHEEKVIKDRRHHLKTY
PNCFVAKELIDWLIEHKEASDRETAIKLMQKLADRGIIHHVCDEHKEFKDVKLFYRFRKD
DGTFPLDNEVKAFMRGQRLYEKLMSPENTLLQPREEEGVKYERTFMASEFLDWLVQEGEA
TTRKEAEQLCHRLMEHGIIQHVSNKHPFVDSNLLYQFRMNFRRRRRLMELLNEKSPSSQE
THDSPFCLRKQSHDNRKSTSFMSVSPSKEIKIVSAVRRSSMSSCGSSGYFSSSPTLSSSP
PVLCNPKSVLKRPVTSEELLTPGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGP
AAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVMEVMEELEC
NT seq 1230 nt   +upstreamnt  +downstreamnt
atggaggagggcggcagcactggcagtgctggcagtgacagcagcaccagcgggagtggc
ggggcgcagcaaagggagctggagcgcatggctgaggtcttggtcaccggggaacagcta
cggctcaggctgcacgaagaaaaggttattaaagatagacgtcatcatctcaagacctac
ccaaactgttttgtcgcaaaagaactgattgactggctgattgaacacaaagaggcttct
gacagagagacggcaattaaactcatgcagaaattagcagaccggggcattattcaccat
gtgtgtgatgagcataaggaattcaaggatgtcaaactcttctaccgctttagaaaggat
gacggcaccttcccattggataatgaagtgaaggcctttatgagaggacagaggctatat
gaaaagctgatgagccctgaaaacacactcctgcagcccagggaggaggaaggggtcaag
tatgagcgcaccttcatggcatctgaattcctggactggctggttcaggaaggtgaggcc
accacgaggaaagaggcagagcagctttgccaccggcttatggagcatggcatcatccag
catgtgtccaacaagcacccatttgtggacagcaatcttctctaccagttcagaatgaac
ttccggcggaggcgaagactgatggagctgctcaatgaaaagtccccctcctcccaggaa
actcatgacagtcccttctgcctgaggaagcagagccatgacaatcggaaatctaccagc
tttatgtcagtgagccccagcaaggagatcaagatcgtgtctgcagtgaggagaagcagc
atgagcagctgtggcagcagcggctacttcagcagcagccccaccctcagcagcagcccc
cctgtgctctgcaaccccaagtccgtgctgaagagacctgtcacctctgaggaactcctt
actcccggggctccgtatgcaaggaagacattcacgattgttggtgacgcggttggctgg
ggttttgtggtgcgaggaagtaagccatgccacatccaggctgtagaccccagtggccct
gcagccgcagcaggaatgaaggtctgtcagtttgtcgtctctgtcaacgggctcaatgtc
ctgcatgtagactaccggaccgtgagcaatctgattctgacgggcccacggacgattgtc
atggaagtcatggaggagttagagtgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (10)   
   KEGG NETWORK (10)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (24)   
   RefSeq(nuc) (2)   
   GenBank (11)   
   EMBL (11)   
3D Structure (9)   
   PDB (9)   
Protein domain (4)   
   Pfam (4)   
All databases (72)   

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