KEGG   Homo sapiens (human): 65109
Entry
65109             CDS       T01001                                 
Symbol
UPF3B, HUPF3B, MRX62, MRX82, MRXS14, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X, Upf3p-X
Name
(RefSeq) UPF3B regulator of nonsense mediated mRNA decay
  KO
K14328  regulator of nonsense transcripts 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa03015  mRNA surveillance pathway
Disease
H00658  X-linked syndromic intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    65109 (UPF3B)
   03015 mRNA surveillance pathway
    65109 (UPF3B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    65109 (UPF3B)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Surveillance complex
     65109 (UPF3B)
   mRNA cycle factors
    P-body specific factors
     65109 (UPF3B)
SSDB
Motif
Pfam: Smg4_UPF3 RRM_1
Other DBs
NCBI-GeneID: 65109
NCBI-ProteinID: NP_542199
OMIM: 300298
HGNC: 20439
Ensembl: ENSG00000125351
UniProt: Q9BZI7
Structure
Position
X:complement(119805311..119852963)
AA seq 483 aa
MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP
TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL
DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET
LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE
KRKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREK
AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL
RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTE
KKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEG
GEE
NT seq 1452 nt   +upstreamnt  +downstreamnt
atgaaggaagagaaggagcacaggcctaaggagaagcgagtaaccctgttaacccccgcc
ggggccacaggcagcggtggtgggacctcgggggacagctccaagggggaagataagcag
gatcgcaacaaggagaagaaagaagcgctgagcaaggtggtaattcgaagattacctccc
actttgaccaaggagcagcttcaggaacatcttcaacctatgcctgagcatgattatttt
gagtttttttctaatgatacgagtttgtatcctcatatgtatgccagagcatacatcaac
tttaaaaaccaagaggacattattttgttcagggatcgctttgatggttatgtattcctt
gacaataaaggtcaggaatatcccgctatagtagaatttgcaccttttcaaaaagctgca
aaaaagaagactaagaaaagagataccaaagtcgggactatcgatgatgatccagaatat
agaaagtttttggaaagttatgccacagataatgagaaaatgacatctactccagagaca
ctgctagaggaaatagaagcaaaaaatagagaattaatagctaaaaagacaaccccactt
ttgagcttcctgaaaaacaagcagagaatgagagaagaaaagagagaagaaaggaggagg
agagaaatagaaagaaaaagacaaagagaagaagagaggaggaaatggaaagaagaagag
aaacgaaaaaggaaagatatagaaaagctaaagaagatagacagaattccagaaagggac
aaattaaaggatgaaccaaagattaaggtacacaggtttctgttacaagctgtgaatcag
aaaaatctgctcaagaagccagaaaaaggagatgaaaaagaattggacaaaagagaaaaa
gccaagaaattggacaaagagaatctcagtgatgaaagagccagtgggcaaagttgtaca
ttgcccaagcgttctgatagcgaacttaaagatgaaaaaccaaagagacctgaagatgag
agcggcagagactatagggagagggaacgggaatatgaacgagatcaggagcgcatactt
cgagaaagagagaggctgaagcggcaagaagaagagcgccgtaggcagaaggagcgctat
gagaaagagaagacttttaagagaaaagaagaagaaatgaaaaaagagaaagacacactt
cgggataaaggaaagaaggctgaaagtacagaatcaataggcagctcagaaaaaactgaa
aagaaagaagaagtggtcaagagagatcgaataagaaacaaggatcgtccagcgatgcag
ctttaccaaccaggagctcgaagccgaaatcgactctgtccccctgatgacagcaccaag
tctggagattcagcagcagaaaggaagcaggaaagtggtattagccatagaaaagaagga
ggagaggagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (36)   
   RefSeq(nuc) (12)   
   GenBank (12)   
   EMBL (12)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (83)   

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