KEGG   Homo sapiens (human): 652968
Entry
652968            CDS       T01001                                 
Symbol
CASTOR1, GATSL3
Name
(RefSeq) cytosolic arginine sensor for mTORC1 subunit 1
  KO
K23080  cytosolic arginine sensor for mTORC1 subunit 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
Drug target
Sapanisertib: D11183
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    652968 (CASTOR1)
SSDB
Motif
Pfam: ACT_7 CASTOR1_ACT-like Castor1_N
Other DBs
NCBI-GeneID: 652968
NCBI-ProteinID: NP_001032755
OMIM: 617034
HGNC: 34423
Ensembl: ENSG00000239282
UniProt: Q8WTX7
Structure
Position
22:complement(30285117..30289505)
AA seq 329 aa
MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGF
KELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQT
DFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSP
QNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIV
MDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYIST
FNFDHALVPEDGIGSVIEVLQRRQEGLAS
NT seq 990 nt   +upstreamnt  +downstreamnt
atggagctgcacatcctagaacaccgggtgcgggtgctgagcgtcgcccgtcccggtctc
tggctctacacccacccgctcatcaagctgctcttcctgccccgccgcagccggtgcaag
ttcttcagcctgacggagacccctgaggattacacgcttatggtggacgaggagggcttt
aaagagctgcccccatctgagttcctgcaagtagctgaggccacatggctggtgctgaac
gtgtcgtctcacagcggtgcggcagtgcaggctgctggggtcaccaagatcgcccgttcg
gtcatcgcgccactggccgagcaccacgtgtctgtgctgatgctgtccacttaccagacg
gacttcatcctggtgcgggagcaggacctgtccgtggtgatccacacgctggcccaggag
ttcgacatttaccgcgaggtgggcggagagcctgtgcctgtgacgagggatgattccagc
aatggctttccccgcactcagcatgggcccagccccacggtgcatcccatccagagccca
cagaaccgcttctgtgtcctcacactggaccctgagacgcttccagccatcgccaccacc
ctcatagatgtcctcttctactcgcacagcacccccaaggaggcagcctctagcagtcct
gaacccagctccatcacgttctttgccttctccctcatcgagggttatatctccattgtc
atggatgctgaaacacagaaaaagttccccagtgacctcctgctgaccagctcctcgggg
gagctgtggaggatggtgcgcatcggtggacagcccctgggctttgatgaatgtggcatc
gtggcacagattgcaggtcccctggctgccgctgacatctctgcctactacatcagcacc
ttcaacttcgaccacgccctggtgcccgaggacggtatcggcagcgtcatcgaggtcctc
cagcggcggcaggaaggcctggcttcctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   Pfam (3)   
All databases (39)   

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