KEGG   Homo sapiens (human): 6554
Entry
6554              CDS       T01001                                 
Symbol
SLC10A1, FHCA2, NTCP
Name
(RefSeq) solute carrier family 10 member 1
  KO
K14341  solute carrier family 10 (sodium/bile acid cotransporter), member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04976  Bile secretion
hsa05161  Hepatitis B
Disease
H01935  Familial hypercholanemia
Drug target
Maralixibat (DG02832): D10951
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6554 (SLC10A1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    6554 (SLC10A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6554 (SLC10A1)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC10: Sodium bile salt cotransporter
   6554 (SLC10A1)
SSDB
Motif
Pfam: SBF SBF_like GAPT Gaa1 DUF2427
Other DBs
NCBI-GeneID: 6554
NCBI-ProteinID: NP_003040
OMIM: 182396
HGNC: 10905
Ensembl: ENSG00000100652
UniProt: Q14973 B2RA41
Structure
Position
14:complement(69775416..69797241)
AA seq 349 aa
MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKG
LAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSI
VMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKR
PQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVL
SALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLL
IAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
NT seq 1050 nt   +upstreamnt  +downstreamnt
atggaggcccacaacgcgtctgccccattcaacttcaccctgccacccaactttggcaag
cgccccacagacctggcactgagcgtcatcctggtgttcatgttgttcttcatcatgctc
tcgctgggctgcaccatggagttcagcaagatcaaggctcacttatggaagcctaaaggg
ctggccatcgccctggtggcacagtatggcatcatgcccctcacggcctttgtgctgggc
aaggtcttccggctgaagaacattgaggcactggccatcttggtctgtggctgctcacct
ggagggaacctgtccaatgtcttcagtctggccatgaagggggacatgaacctcagcatt
gtgatgaccacctgctccaccttctgtgcccttggcatgatgcctctcctcctgtacatc
tactccagggggatctatgatggggacctgaaggacaaggtgccctataaaggcatcgtg
atatcactggtcctggttctcattccttgcaccatagggatcgtcctcaaatccaaacgg
ccacaatacatgcgctatgtcatcaagggagggatgatcatcattctcttgtgcagtgtg
gccgtcacagttctctctgccatcaatgtggggaagagcatcatgtttgccatgacacca
ctcttgattgccacctcctccctgatgccttttattggctttctgctgggttatgttctc
tctgctctcttctgcctcaatggacggtgcagacgcactgtcagcatggagactggatgc
caaaatgtccaactctgttccaccatcctcaatgtggcctttccacctgaagtcattgga
ccacttttcttctttcccctcctctacatgattttccagcttggagaagggcttctcctc
attgccatattttggtgctatgagaaattcaagactcccaaggataaaacaaaaatgatc
tacacagctgccacaactgaagaaacaattccaggagctctgggaaatggcacctacaaa
ggggaggactgctccccttgcacagcctag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (19)   
   RefSeq(nuc) (1)   
   GenBank (9)   
   EMBL (9)   
3D Structure (7)   
   PDB (7)   
Protein domain (5)   
   Pfam (5)   
All databases (53)   

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