KEGG   Homo sapiens (human): 6555
Entry
6555              CDS       T01001                                 
Symbol
SLC10A2, ASBT, IBAT, ISBT, NTCP2, PBAM, PBAM1
Name
(RefSeq) solute carrier family 10 member 2
  KO
K14342  solute carrier family 10 (sodium/bile acid cotransporter), member 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04976  Bile secretion
Disease
H01016  Primary bile acid malabsorption
Drug target
Elobixibat (DG01924): D10795<JP> D10796
Linerixibat: D11539
Maralixibat (DG02832): D10951
Maralixibat chloride: D10952<US>
Odevixibat: D11716<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    6555 (SLC10A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6555 (SLC10A2)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC10: Sodium bile salt cotransporter
   6555 (SLC10A2)
SSDB
Motif
Pfam: SBF
Other DBs
NCBI-GeneID: 6555
NCBI-ProteinID: NP_000443
OMIM: 601295
HGNC: 10906
Ensembl: ENSG00000125255
UniProt: Q12908
Position
13:complement(103043998..103066417)
AA seq 348 aa
MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLG
HIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVD
GDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVSLVVPVSIGM
FVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSL
GFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAF
AAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
NT seq 1047 nt   +upstreamnt  +downstreamnt
atgaatgatccgaacagctgtgtggacaatgcaacagtttgctctggtgcatcctgtgtg
gtacctgagagcaatttcaataacatcctaagtgtggtcctaagtacggtgctgaccatc
ctgttggccttggtgatgttctccatgggatgcaacgtggaaatcaagaaatttctaggg
cacataaagcggccgtggggcatttgtgttggcttcctctgtcagtttggaatcatgccc
ctcacaggattcatcctgtcggtggcctttgacatcctcccgctccaggccgtagtggtg
ctcattataggatgctgccctggaggaactgcctccaatatcttggcctattgggtcgat
ggcgacatggacctgagcgtcagcatgaccacatgctccacactgcttgccctcggaatg
atgccgctgtgcctccttatctataccaaaatgtgggtcgactctgggagcatcgtaatt
ccctatgataacataggtacatctctggtttctctcgttgttcctgtttccattggaatg
tttgttaatcacaaatggccccaaaaagcaaagatcatacttaaaattgggtccatcgcg
ggcgccatcctcattgtgctcatagctgtggttggaggaatattgtaccaaagcgcctgg
atcattgctcccaaactgtggattataggaacaatatttcctgtggcgggttactccctg
gggtttcttctggctagaattgctggtctaccctggtacaggtgccgaacggttgctttt
gaaacggggatgcagaacacgcagctatgttccaccatcgttcagctctccttcactcct
gaggagctcaatgtcgtattcaccttcccgctcatctacagcattttccagctcgccttt
gccgcaatattcttaggattttatgtggcatacaagaaatgtcatggaaaaaacaaggca
gaaattccagagagcaaagaaaatggaacggagccagagtcatcgttttataaggcaaat
ggaggatttcaacctgacgaaaagtag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (32)   

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