KEGG   Homo sapiens (human): 6560
Entry
6560              CDS       T01001                                 
Symbol
SLC12A4, CTC-479C5.17, KCC1, hKCC1
Name
(RefSeq) solute carrier family 12 member 4
  KO
K14427  solute carrier family 12 (potassium/chloride transporter), member 4/6
Organism
hsa  Homo sapiens (human)
Drug target
Bumetanide: D00247<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    6560 (SLC12A4)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC12: Electroneutral cation-coupled Cl cotransporter
   6560 (SLC12A4)
SSDB
Motif
Pfam: AA_permease SLC12 AA_permease_2
Other DBs
NCBI-GeneID: 6560
NCBI-ProteinID: NP_005063
OMIM: 604119
HGNC: 10913
Ensembl: ENSG00000124067
UniProt: Q9UP95
Structure
Position
16:complement(67943474..67968694)
AA seq 1085 aa
MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAELDDSDGHGNHRESSPFLSPLEASRGID
YYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGT
LMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVV
PAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGA
HDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIF
DPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLN
NVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSF
TVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGV
VLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIP
FLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQT
LLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKE
WGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKA
GKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQS
CGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHER
YLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLY
HLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSAL
RLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMH
TAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREV
ITIYS
NT seq 3258 nt   +upstreamnt  +downstreamnt
atgcctcacttcaccgtggtgccagtggacgggccgaggcgcggcgactatgacaacctc
gaggggctcagttgggtggactacggggagcgcgccgagctggatgactcggacggacat
ggcaaccacagagagagcagcccttttctttcccccttggaggcttccagaggaattgac
tactatgacaggaacctggcactgtttgaggaagagctggacatccgcccaaaggtatcg
tctcttctgggaaagctcgtcagctacaccaacctcacccagggcgccaaagagcatgag
gaggccgagagtggggagggcacccgccggagggcagccgaggcacccagcatgggcacc
ctcatgggggtgtacctgccctgcctgcagaatatctttggggttatcctcttcctgcgg
ctgacctggatggtgggcacagcaggtgtgctacaggccctcctcatcgtgcttatctgc
tgctgttgtaccctgctgacggccatctccatgagtgccatcgccaccaacggtgtggtt
ccagctgggggctcctatttcatgatctctcgttcactggggccagaatttggaggtgct
gtgggcctgtgcttctacctgggaacaacattcgcagcagccatgtacatcctgggggcc
atcgagatcttgctgacctacattgccccaccagctgccattttttacccatcgggtgct
catgacacgtcgaatgccactttgaacaatatgcgtgtgtatgggaccattttcctgacc
ttcatgaccctggtggtgtttgtgggggtcaagtatgtgaacaaatttgcctcgctcttc
ctggcctgtgtgatcatctccatcctctccatctatgctgggggcataaagtctatattt
gaccctcccgtgtttccggtatgcatgctgggcaacaggaccctgtcccgggaccagttt
gacatctgtgccaagacagctgtagtggacaatgagacagtggccacccagctatggagt
ttcttctgccacagccccaaccttacgaccgactcctgtgacccctacttcatgctcaac
aatgtgaccgagatccctggcatccccggggcagctgctggtgtgctccaggaaaacctg
tggagcgcctacctggagaagggtgacatcgtggagaagcatgggctgccctccgcagat
gccccgagcctgaaggagagcctgcctctgtacgtggtcgctgacatcgccacatccttc
accgtgctggtcggcatcttcttcccttctgtaacaggcatcatggctggctcaaaccgc
tctggggaccttcgtgacgcccagaagtctatccctgtggggaccattctggccatcatt
acaacttccctcgtgtacttcagcagtgtggttctctttggtgcctgcattgagggtgtg
gttctccgggacaagtatggcgatggtgtcagcaggaacttggtggtgggcacactggcc
tggccttcaccctgggtcatcgtcatcggctccttcttttcaacgtgtggcgctggcctc
cagagcctcacaggggcaccacgcctattgcaggccattgccaaggacaacatcatcccc
ttcctccgggtgtttggccacgggaaggtgaatggtgaacccacatgggcactcctcctg
acggcactcatcgccgagctgggcatcctcatcgcctccctcgacatggtggcccccatc
ttatccatgttctttctgatgtgctacctgttcgtgaacctcgcctgtgcggtgcagaca
ctcctgaggacccccaactggcggccccggttcaagtactatcactgggcgctgtccttc
ctgggcatgagtctctgcctggcccttatgtttgtctcctcctggtactatgccctggtg
gccatgctcatcgccggcatgatctacaaatacatcgagtaccaaggggctgagaaggag
tggggtgacgggatccgaggcctgtccctgagcgctgcccgctacgcgctgttgcggctg
gaggaggggcctcctcacaccaagaactggcggccgcagctgctggtgctgctgaagctg
gacgaggacctccacgtgaagtacccgcggctcctcaccttcgcctcccagctcaaggct
ggcaagggcctgaccattgttggttctgtcatccaggggagcttcttggagagctatggc
gaggctcaggccgccgagcagaccatcaagaacatgatggaaattgagaaggtgaagggc
ttctgccaggtggtggtggccagcaaggtgcgggaggggctggcccacctcatccagtcc
tgtggcctgggaggcatgcggcataactccgtggtgctgggctggccctacggctggcga
cagagcgaggacccccgtgcctggaagaccttcattgacaccgtgcgctgcactacggct
gcccacctggccctgctcgtgcccaagaacatcgccttctaccccagcaaccacgagcgc
tacctggagggccacatagacgtgtggtggatcgtgcacgatggtggcatgctcatgctt
ctgcccttcctgctgcgccagcataaggtctggaggaagtgccggatgcgcatcttcaca
gtggcccagatggatgacaacagcatccagatgaagaaggacctggctgtctttctgtac
catctgcgccttgaggccgaggtggaggtggtggagatgcataacagtgacatctctgca
tacacctacgagcggacgctgatgatggagcagcggtcgcagatgctgcggcagatgaga
ctgaccaagactgagcgggagcgagaagcccagctggtcaaggatcggcactcggccctg
cggctggagagcctgtactcggacgaggaagatgagtctgcagtgggggctgacaagatc
cagatgacgtggaccagggacaagtacatgactgagacctgggaccccagccatgcccct
gacaatttccgggagctggtgcacattaagccggaccaatccaatgtgcggcgcatgcac
actgctgtgaagctcaatgaagtcattgtcacgcgctcccacgacgcccgcctggttctc
ctaaacatgcctggcccacccaggaacagtgagggcgacgagaactacatggagttcctc
gaggtgctgaccgagggccttgagcgggtgctgttggtgcgcggtggtggccgtgaagtc
atcaccatctactcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (49)   
   RefSeq(nuc) (5)   
   GenBank (22)   
   EMBL (22)   
3D Structure (8)   
   PDB (8)   
Protein domain (3)   
   Pfam (3)   
All databases (92)   

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