KEGG   Homo sapiens (human): 6586
Entry
6586              CDS       T01001                                 
Symbol
SLIT3, MEGF5, SLIL2, SLIT1, Slit-3, slit2
Name
(RefSeq) slit guidance ligand 3
  KO
K06850  slit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    6586 (SLIT3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    6586 (SLIT3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Axon guidance molecules
   6586 (SLIT3)
SSDB
Motif
Pfam: LRR_8 EGF LRR_4 LRR_5 hEGF Laminin_G_2 LRRNT LRR_9 Laminin_G_1 LRRCT EGF_3 JAG1-like_EGF2 DL-JAG_EGF-like
Other DBs
NCBI-GeneID: 6586
NCBI-ProteinID: NP_003053
OMIM: 603745
HGNC: 11087
Ensembl: ENSG00000184347
UniProt: O75094
Position
5:complement(168661740..169301139)
AA seq 1523 aa
MAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIP
RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK
LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL
RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT
LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLME
IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL
VLYGNKITEIVKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK
GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS
KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN
DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV
FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL
LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ
LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLI
DLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE
GSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPT
HRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI
QNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVC
ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVA
HKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE
PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD
NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPK
SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA
LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG
KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG
EHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQ
CTDGSSFVEEVERHLECGCLACS
NT seq 4572 nt   +upstreamnt  +downstreamnt
atggcccccgggtgggcaggggtcggcgccgccgtgcgcgcccgcctggcgctggccttg
gcgctggcgagcgtcctgagtgggcctccagccgtcgcctgccccaccaagtgtacctgc
tccgctgccagcgtggactgccacgggctgggcctccgcgcggttcctcggggcatcccc
cgcaacgctgagcgccttgacctggacagaaataatatcaccaggatcaccaagatggac
ttcgctgggctcaagaacctccgagtcttgcatctggaagacaaccaggtcagcgtcatc
gagagaggcgccttccaggacctgaagcagctagagcgactgcgcctgaacaagaataag
ctgcaagtccttccagaattgcttttccagagcacgccgaagctcaccagactagatttg
agtgaaaaccagatccaggggatcccgaggaaggcgttccgcggcatcaccgatgtgaag
aacctgcaactggacaacaaccacatcagctgcattgaagatggagccttccgagcgctg
cgcgatttggagatccttaccctcaacaacaacaacatcagtcgcatcctggtcaccagc
ttcaaccacatgccgaagatccgaactctgcgcctccactccaaccacctgtactgcgac
tgccacctggcctggctctcggattggctgcgacagcgacggacagttggccagttcaca
ctctgcatggctcctgtgcatttgaggggcttcaacgtggcggatgtgcagaagaaggag
tacgtgtgcccagccccccactcggagcccccatcctgcaatgccaactccatctcctgc
ccttcgccctgcacgtgcagcaataacatcgtggactgtcgaggaaagggcttgatggag
attcctgccaacttgccggagggcatcgtcgaaatacgcctagaacagaactccatcaaa
gccatccctgcaggagccttcacccagtacaagaaactgaagcgaatagacatcagcaag
aatcagatatcggatattgctccagatgccttccagggcctgaaatcactcacatcgctg
gtcctgtatgggaacaagatcaccgagattgtcaagggactgtttgatgggctggtgtcc
ctacagctgctcctcctcaatgccaacaagatcaactgcctgcgggtgaacacgtttcag
gacctgcagaacctcaacttgctctccctgtatgacaacaagctgcagaccatcagcaag
gggctcttcgcccctctgcagtccatccagacactccacttagcccaaaacccatttgtg
tgcgactgccacttgaagtggctggccgactacctccaggacaaccccatcgagacaagc
ggggcccgctgcagcagcccgcgccgactcgccaacaagcgcatcagccagatcaagagc
aagaagttccgctgctcaggctccgaggattaccgcagcaggttcagcagcgagtgcttc
atggacctcgtgtgccccgagaagtgtcgctgtgagggcacgattgtggactgctccaac
cagaagctggtccgcatcccaagccacctccctgaatatgtcaccgacctgcgactgaat
gacaatgaggtatctgttctggaggccactggcatcttcaagaagttgcccaacctgcgg
aaaataaatctgagtaacaataagatcaaggaggtgcgagagggagctttcgatggagca
gccagcgtgcaggagctgatgctgacagggaaccagctggagaccgtgcacgggcgcgtg
ttccgtggcctcagtggcctcaaaaccttgatgctgaggagtaacttgatcggctgtgtg
agtaatgacacctttgccggcctgagttcggtgagactgctgtccctctatgacaatcgg
atcaccaccatcacccctggggccttcaccacgcttgtctccctgtccaccataaacctc
ctgtccaaccccttcaactgcaactgccacctggcctggctcggcaagtggttgaggaag
aggcggatcgtcagtgggaaccctaggtgccagaagccatttttcctcaaggagattccc
atccaggatgtggccatccaggacttcacctgtgatggcaacgaggagagtagctgccag
ctgagcccgcgctgcccggagcagtgcacctgtatggagacagtggtgcgatgcagcaac
aaggggctccgcgccctccccagaggcatgcccaaggatgtgaccgagctgtacctggaa
ggaaaccacctaacagccgtgcccagagagctgtccgccctccgacacctgacgcttatt
gacctgagcaacaacagcatcagcatgctgaccaattacaccttcagtaacatgtctcac
ctctccactctgatcctgagctacaaccggctgaggtgcatccccgtccacgccttcaac
gggctgcggtccctgcgagtgctaaccctccatggcaatgacatttccagcgttcctgaa
ggctccttcaacgacctcacatctctttcccatctggcgctgggaaccaacccactccac
tgtgactgcagtcttcggtggctgtcggagtgggtgaaggcggggtacaaggagcctggc
atcgcccgctgcagtagccctgagcccatggctgacaggctcctgctcaccaccccaacc
caccgcttccagtgcaaagggccagtggacatcaacattgtggccaaatgcaatgcctgc
ctctccagcccgtgcaagaataacgggacatgcacccaggaccctgtggagctgtaccgc
tgtgcctgcccctacagctacaagggcaaggactgcactgtgcccatcaacacctgcatc
cagaacccctgtcagcatggaggcacctgccacctgagtgacagccacaaggatgggttc
agctgctcctgccctctgggctttgaggggcagcggtgtgagatcaacccagatgactgt
gaggacaacgactgcgaaaacaatgccacctgcgtggacgggatcaacaactacgtgtgt
atctgtccgcctaactacacaggtgagctatgcgacgaggtgattgaccactgtgtgcct
gagctgaacctctgtcagcatgaggccaagtgcatccccctggacaaaggattcagctgc
gagtgtgtccctggctacagcgggaagctctgtgagacagacaatgatgactgtgtggcc
cacaagtgccgccacggggcccagtgcgtggacacaatcaatggctacacatgcacctgc
ccccagggcttcagtggacccttctgtgaacaccccccacccatggtcctactgcagacc
agcccatgcgaccagtacgagtgccagaacggggcccagtgcatcgtggtgcagcaggag
cccacctgccgctgcccaccaggcttcgccggccccagatgcgagaagctcatcactgtc
aacttcgtgggcaaagactcctacgtggaactggcctccgccaaggtccgaccccaggcc
aacatctccctgcaggtggccactgacaaggacaacggcatccttctctacaaaggagac
aatgaccccctggcactggagctgtaccagggccacgtgcggctggtctatgacagcctg
agttcccctccaaccacagtgtacagtgtggagacagtgaatgatgggcagtttcacagt
gtggagctggtgacgctaaaccagaccctgaacctagtagtggacaaaggaactccaaag
agcctggggaagctccagaagcagccagcagtgggcatcaacagccccctctaccttgga
ggcatccccacctccaccggcctctctgccttgcgccagggcacggaccggcctctaggc
ggcttccacggatgcatccatgaggtgcgcatcaacaacgagctgcaggacttcaaggcc
ctcccaccacagtccctgggggtgtcaccaggctgcaagtcctgcaccgtgtgcaagcac
ggcctgtgccgctccgtggagaaggacagcgtggtgtgcgagtgccgcccaggctggacc
ggcccactctgcgatcaggaggcccgggacccctgcctcggccacagatgccaccatgga
aaatgtgtggcaactgggacctcatacatgtgcaagtgtgccgagggctatggaggggac
ttgtgtgacaacaagaatgactctgccaatgcctgctcagccttcaagtgtcaccatggg
cagtgccacatctcagaccaaggggagccctactgcctgtgccagcccggctttagcggc
gagcactgccaacaagagaatccgtgcctgggacaagtagtccgagaggtgatccgccgc
cagaaaggttatgcatcatgtgccacagcctccaaggtgcccatcatggaatgtcgtggg
ggctgtgggccccagtgctgccagcccacccgcagcaagcggcggaaatacgtcttccag
tgcacggacggctcctcgtttgtagaagaggtggagagacacttagagtgcggctgcctc
gcgtgttcctaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
Protein domain (13)   
   Pfam (13)   
All databases (91)   

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