KEGG   Homo sapiens (human): 65985
Entry
65985             CDS       T01001                                 
Symbol
AACS, ACSF1, SUR-5
Name
(RefSeq) acetoacetyl-CoA synthetase
  KO
K01907  acetoacetyl-CoA synthetase [EC:6.2.1.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00280  Valine, leucine and isoleucine degradation
hsa00650  Butanoate metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    65985 (AACS)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    65985 (AACS)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:hsa01004]
    65985 (AACS)
Enzymes [BR:hsa01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.16  acetoacetate---CoA ligase
     65985 (AACS)
Lipid biosynthesis proteins [BR:hsa01004]
 Acyl-CoA synthetase
  Short/medium chain acyl-CoA synthetase
   65985 (AACS)
SSDB
Motif
Pfam: AMP-binding ACAS_N AMP-binding_C
Other DBs
NCBI-GeneID: 65985
NCBI-ProteinID: NP_076417
OMIM: 614364
HGNC: 21298
Ensembl: ENSG00000081760
UniProt: Q86V21
Position
12:125065435..125143316
AA seq 672 aa
MSKEERPGREEILECQVMWEPDSKKNTQMDRFRAAVGAACGLALESYDDLYHWSVESYSD
FWAEFWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIAR
EGKEEIVKVTFEELRQEVALFAAAMRKMGVKKGDRVVGYLPNSEHAVEAMLAAASIGAIW
SSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHNHMEKLQQVVKGLPDLKKVVVIP
YVSSRENIDLSKIPNSVFLDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCM
VHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSLLATGAAMVLYDGSPLV
PTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQSYE
YVYRCIKSSILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWNEEGKAVWG
ESGELVCTKPIPCQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPKTGGIVMLGRS
DGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMASGHAFQPDLV
KRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQIIAGKAVEQGGAFSNPETL
DLYRDIPELQGF
NT seq 2019 nt   +upstreamnt  +downstreamnt
atgtccaaggaggagcgccccggtcgggaggagatcctggagtgccaggtgatgtgggag
cctgacagtaagaagaacacgcagatggaccgcttccgggcggctgtgggcgccgcctgc
ggcctggcgctggagagttatgatgacttgtaccattggtccgttgagtcatattcagac
ttctgggcagagttctggaaattcagtggaattgtcttctcacgtgtgtatgatgaggtt
gtggacacatcgaaaggaatcgcagatgtccccgagtggttcaaaggcagtcggctcaac
tatgcagaaaacctcctgcggcacaaagagaatgacagagttgccctttacattgcaagg
gaaggcaaagaggaaattgtgaaggtgacttttgaagagctgaggcaagaagtggctttg
tttgcagcagcaatgaggaaaatgggtgtgaagaaaggagatcgggttgttggttattta
cccaacagtgagcacgctgtcgaggcgatgctggctgcggcaagcattggtgccatctgg
agctccacgtccccggacttcggtgtgaatggtgtgctggaccggttttctcaaattcag
ccaaagctcatcttctctgtggaggctgttgtctataatggcaaagagcacaaccacatg
gaaaagctgcagcaggtggttaaaggcctaccagacttgaagaaagtggtggtgattcct
tatgtgtcctccagagagaacatagacctttcaaagattccaaacagtgtgtttctggat
gactttcttgccaccggcaccagtgagcaggccccgcagctggagttcgagcagctgccc
ttcagccacccactgttcatcatgttctcatcgggcaccacgggcgcacccaagtgcatg
gtgcattccgctgggggcaccctcatccagcatctgaaggagcacctgctgcacggcaac
atgaccagcagtgacatcctcctgtgctacaccacggtcggctggatgatgtggaactgg
atggtgtcccttctggccacaggagcggccatggtcttgtacgatggctcccccctggtg
cccacgcccaatgtgctctgggacctggttgacaggataggcatcactgtcctggtaact
ggggccaagtggctgtcagtgctggaagagaaggccatgaagccggtggaaacccacagt
ctccagatgctccacacgatcctgtccactggctccccactgaaagcccagagctacgag
tatgtctacaggtgcatcaagagcagcatcctcctgggctccatctcaggaggcaccgac
atcatctcctgcttcatgggccacaatttttctcttcctgtgtataaaggggagattcag
gcccggaacctgggcatggccgtggaagcgtggaacgaggaaggaaaggcggtctgggga
gagagcggcgagctggtgtgtactaagccgatcccttgccagcccacacacttctggaac
gatgagaacggcaacaagtacaggaaggcgtatttctccaaattcccaggtatctgggct
catggcgactactgcagaatcaaccccaagaccgggggcatcgtcatgcttggccggagt
gacggcaccctcaaccccaacggggtgcggttcggcagctcggaaatctataacattgtg
gaatccttcgaggaggtggaggacagcctgtgtgtcccccagtataacaagtacagggag
gagagggtgatcctcttcctgaagatggcctccgggcacgccttccagcctgacttggtt
aagaggatccgtgacgccatccgcatgggcttgtctgcgcgacacgtgcccagcctcatc
ctggaaaccaagggcatcccgtatacgctcaacggcaagaaagtggaagttgccgtcaaa
cagatcatcgctggaaaagccgtggagcaaggaggtgctttctcgaaccccgagaccctg
gatctgtaccgggacatccctgagctgcagggcttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (53)   
   RefSeq(nuc) (15)   
   GenBank (19)   
   EMBL (19)   
Protein domain (3)   
   Pfam (3)   
All databases (104)   

Download RDF
DBGET integrated database retrieval system