KEGG   Homo sapiens (human): 6611
Entry
6611              CDS       T01001                                 
Symbol
SMS, MRSR, MRXSSR, SPMSY, SRS, SpS
Name
(RefSeq) spermine synthase
  KO
K00802  spermine synthase [EC:2.5.1.22]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa00480  Glutathione metabolism
hsa01100  Metabolic pathways
Network
nt06033  Glycine, serine and arginine metabolism
  Element
N01623  Spermine biosynthesis
Disease
H00597  Snyder-Robinson syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    6611 (SMS)
   00330 Arginine and proline metabolism
    6611 (SMS)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    6611 (SMS)
Enzymes [BR:hsa01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.22  spermine synthase
     6611 (SMS)
SSDB
Motif
Pfam: Spermine_synth SpmSyn_N Spermine_synt_N BpsA_C
Other DBs
NCBI-GeneID: 6611
NCBI-ProteinID: NP_004586
OMIM: 300105
HGNC: 11123
Ensembl: ENSG00000102172
UniProt: P52788
Structure
Position
X:21940709..21994837
AA seq 366 aa
MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFAN
LRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAI
DRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRA
IMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV
LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD
LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTV
WKKAKP
NT seq 1101 nt   +upstreamnt  +downstreamnt
atggcagcagcacggcacagcacgctcgacttcatgctcggcgccaaagctgatggtgag
accattctaaaaggcctccagtccattttccaggagcaggggatggcggagtcggtgcac
acctggcaggaccatggctatttagcaacctacacaaacaagaacggcagctttgccaat
ttgagaatttacccacatggattggtgttgctggaccttcagagttatgatggtgatgcg
caaggcaaagaagagatcgacagtattttgaacaaagtagaggaaagaatgaaagaattg
agtcaggacagtactgggcgggtgaaacgattaccacccatagtgcgaggaggagccatc
gacagatactggcccaccgccgacgggcgcctggttgaatatgacatagatgaagtggta
tatgacgaagattcaccttatcaaaatataaaaattctacactcgaagcagtttggaaat
attctcatccttagtggggatgttaatttggcagagagtgatttggcatatacccgggcc
atcatgggcagtggcaaagaagattacactggcaaagatgtactcattctgggaggtgga
gacggaggcatattgtgtgaaatagtcaaactaaaaccaaagatggtcactatggtagag
attgaccaaatggtgattgatgggtgtaagaaatacatgcgaaaaacgtgtggcgatgtc
ttagacaatcttaaaggagactgctatcaggttctaatagaagactgtatcccggtactg
aagaggtacgccaaagaagggagagaatttgattatgtgattaatgatttgacagctgtt
ccaatctccacgtctccagaagaagattccacatgggagtttctcagactgattcttgac
ctctcaatgaaagtgttgaaacaggatgggaaatattttacacaggggaactgtgtcaat
ctgacagaagcactgtcgctctatgaagaacagctggggcgcctgtattgtcctgtggaa
ttttcaaaggagatcgtctgtgtcccttcatacttggaattgtgggtattttacactgtt
tggaagaaagctaaaccctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (43)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (36)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (17)   
   RefSeq(nuc) (5)   
   GenBank (6)   
   EMBL (6)   
3D Structure (2)   
   PDB (2)   
Protein domain (4)   
   Pfam (4)   
All databases (91)   

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