KEGG   Homo sapiens (human): 6616
Entry
6616              CDS       T01001                                 
Symbol
SNAP25, CMS18, RIC-4, RIC4, SEC9, SNAP, SNAP-25, SUP, bA416N4.2, dJ1068F16.2
Name
(RefSeq) synaptosome associated protein 25
  KO
K18211  synaptosomal-associated protein 25
Organism
hsa  Homo sapiens (human)
Pathway
hsa04721  Synaptic vesicle cycle
hsa04911  Insulin secretion
Disease
H00770  Congenital myasthenic syndrome
Drug target
Botulinum toxin (DG00772): D00783<JP/US> D02735<JP/US> D11405<US>
Daxibotulinumtoxin A: D10921
Incobotulinumtoxin A: D10012<JP/US>
Letibotulinumtoxin A: D10949
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    6616 (SNAP25)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    6616 (SNAP25)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    6616 (SNAP25)
Membrane trafficking [BR:hsa04131]
 SNARE
  SNAP-25 (Qb,c)
   SNAP-25
    6616 (SNAP25)
SSDB
Motif
Pfam: SNAP-25 DUF5089 CTLH LXG COG6_N Sec20 V-SNARE_C
Other DBs
NCBI-GeneID: 6616
NCBI-ProteinID: NP_001309831
OMIM: 600322
HGNC: 11132
Ensembl: ENSG00000132639
UniProt: P60880
Structure
Position
20:10218830..10307418
AA seq 206 aa
MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRV
EEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARV
VDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDR
IMEKADSNKTRIDEANQRATKMLGSG
NT seq 621 nt   +upstreamnt  +downstreamnt
atggccgaagacgcagacatgcgcaatgagctggaggagatgcagcgaagggctgaccag
ttggctgatgagtcgctggaaagcacccgtcgtatgctgcaactggttgaagagagtaaa
gatgctggtatcaggactttggttatgttggatgaacaaggagaacaactcgatcgtgtc
gaagaaggcatgaaccatatcaaccaagacatgaaggaggctgagaaaaatttaaaagat
ttagggaaatgctgtggccttttcatatgtccttgtaacaagcttaaatcaagtgatgct
tacaaaaaagcctggggcaataatcaggacggagtggtggccagccagcctgctcgtgta
gtggacgaacgggagcagatggccatcagtggcggcttcatccgcagggtaacaaatgat
gcccgagaaaatgaaatggatgaaaacctagagcaggtgagcggcatcatcgggaacctc
cgtcacatggccctggatatgggcaatgagatcgatacacagaatcgccagatcgacagg
atcatggagaaggctgattccaacaaaaccagaattgatgaggccaaccaacgtgcaaca
aagatgctgggaagtggttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (58)   
   RefSeq(nuc) (16)   
   GenBank (21)   
   EMBL (21)   
3D Structure (12)   
   PDB (12)   
Protein domain (7)   
   Pfam (7)   
All databases (131)   

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