KEGG   Homo sapiens (human): 6653
Entry
6653              CDS       T01001                                 
Symbol
SORL1, C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
Name
(RefSeq) sortilin related receptor 1
  KO
K24498  sortilin-related receptor
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    6653 (SORL1)
Membrane trafficking [BR:hsa04131]
 Endosome - Golgi transport
  Others
   Others
    6653 (SORL1)
SSDB
Motif
Pfam: Ldl_recept_a Sortilin-Vps10 Sortilin_C fn3 Ldl_recept_b Pur_ac_phosph_N Interfer-bind BNR_6
Other DBs
NCBI-GeneID: 6653
NCBI-ProteinID: NP_003096
OMIM: 602005
HGNC: 11185
Ensembl: ENSG00000137642
UniProt: Q92673
Structure
Position
11:121452314..121633763
AA seq 2214 aa
MATRSSRRESRLPFLFTLVALLPPGALCEVWTQRLHGGSAPLPQDRGFLVVQGDPRELRL
WARGDARGASRADEKPLRRKRSAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVAL
ARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFA
DAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQT
WIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDF
QLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVF
VCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGL
QGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQR
LSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYY
TWGDHGGIITAIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIF
GSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATC
FNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGS
TYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATE
QLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFE
PLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKP
GIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNL
PHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNA
CVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLR
NQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDL
EDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCE
ASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLR
DCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPE
FHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGH
CIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDG
YRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDG
RDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQN
LQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPD
TTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTH
GLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSI
TTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG
SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVEC
TWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSS
DYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSY
KVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVL
LFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQAR
CLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYT
KHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA
NT seq 6645 nt   +upstreamnt  +downstreamnt
atggcgacacggagcagcaggagggagtcgcgactcccgttcctattcaccctggtcgca
ctgctgccgcccggagctctctgcgaagtctggacgcagaggctgcacggcggcagcgcg
cccttgccccaggaccggggcttcctcgtggtgcagggcgacccgcgcgagctgcggctg
tgggcgcgcggggatgccaggggggcgagccgcgcggacgagaagccgctccggaggaaa
cggagcgctgccctgcagcccgagcccatcaaggtgtacggacaggttagtctgaatgat
tcccacaatcagatggtggtgcactgggctggagagaaaagcaacgtgatcgtggccttg
gcccgagatagcctggcattggcgaggcccaagagcagtgatgtgtacgtgtcttacgac
tatggaaaatcattcaagaaaatttcagacaagttaaactttggcttgggaaataggagt
gaagctgttatcgcccagttctaccacagccctgcggacaacaagcggtacatctttgca
gacgcttatgcccagtacctctggatcacgtttgacttctgcaacactcttcaaggcttt
tccatcccatttcgggcagctgatctcctcctacacagtaaggcctccaaccttctcttg
ggctttgacaggtcccaccccaacaagcagctgtggaagtcagatgactttggccagacc
tggatcatgattcaggaacatgtcaagtccttttcttggggaattgatccctatgacaaa
ccaaataccatctacattgaacgacatgaaccctctggctactccactgtcttccgaagt
acagatttcttccagtcccgggaaaaccaggaagtgatccttgaggaagtgagagatttt
cagcttcgggacaagtacatgtttgctacaaaggtggtgcatctcttgggcagtgaacag
cagtcttctgtccagctctgggtctcctttggccggaagcccatgagagcagcccagttt
gtcacaagacatcctattaatgaatattacatcgcagatgcctccgaggaccaggtgttt
gtgtgtgtcagccacagtaacaaccgcaccaatttatacatctcagaggcagaggggctg
aagttctccctgtccttggagaacgtgctctattacagcccaggaggggccggcagtgac
accttggtgaggtattttgcaaatgaaccatttgctgacttccaccgagtggaaggattg
caaggagtctacattgctactctgattaatggttctatgaatgaggagaacatgagatcg
gtcatcacctttgacaaagggggaacctgggagtttcttcaggctccagccttcacggga
tatggagagaaaatcaattgtgagctttcccagggctgttcccttcatctggctcagcgc
ctcagtcagctcctcaacctccagctccggagaatgcccatcctgtccaaggagtcggct
ccaggcctcatcatcgccactggctcagtgggaaagaacttggctagcaagacaaacgtg
tacatctctagcagtgctggagccaggtggcgagaggcacttcctggacctcactactac
acatggggagaccacggcggaatcatcacggccattgcccagggcatggaaaccaacgag
ctaaaatacagtaccaatgaaggggagacctggaaaacattcatcttctctgagaagcca
gtgtttgtgtatggcctcctcacagaacctggggagaagagcactgtcttcaccatcttt
ggctcgaacaaagagaatgtccacagctggctgatcctccaggtcaatgccacggatgcc
ttgggagttccctgcacagagaatgactacaagctgtggtcaccatctgatgagcggggg
aatgagtgtttgctgggacacaagactgttttcaaacggcggaccccccatgccacatgc
ttcaatggagaggactttgacaggccggtggtcgtgtccaactgctcctgcacccgggag
gactatgagtgtgacttcggtttcaagatgagtgaagatttgtcattagaggtttgtgtt
ccagatccggaattttctggaaagtcatactcccctcctgtgccttgccctgtgggttct
acttacaggagaacgagaggctaccggaagatttctggggacacttgtagcggaggagat
gttgaagcgcgactggaaggagagctggtcccctgtcccctggcagaagagaacgagttc
attctgtatgctgtgaggaaatccatctaccgctatgacctggcctcgggagccaccgag
cagttgcctctcaccgggctacgggcagcagtggccctggactttgactatgagcacaac
tgtttgtattggtccgacctggccttggacgtcatccagcgcctctgtttgaatggaagc
acagggcaagaggtgatcatcaattctggcctggagacagtagaagctttggcttttgaa
cccctcagccagctgctttactgggtagatgcaggcttcaaaaagattgaggtagctaat
ccagatggcgacttccgactcacaatcgtcaattcctctgtgcttgatcgtcccagggct
ctggtcctcgtgccccaagagggggtgatgttctggacagactggggagacctgaagcct
gggatttatcggagcaatatggatggttctgctgcctatcacctggtgtctgaggatgtg
aagtggcccaatggcatctctgtggacgaccagtggatttactggacggatgcctacctg
gagtgcatagagcggatcacgttcagtggccagcagcgctctgtcattctggacaacctc
ccgcacccctatgccattgctgtctttaagaatgaaatctactgggatgactggtcacag
ctcagcatattccgagcttccaaatacagtgggtcccagatggagattctggcaaaccag
ctcacggggctcatggacatgaagattttctacaaggggaagaacactggaagcaatgcc
tgtgtgcccaggccatgcagcctgctgtgcctgcccaaggccaacaacagtagaagctgc
aggtgtccagaggatgtgtccagcagtgtgcttccatcaggggacctgatgtgtgactgc
cctcagggctatcagctcaagaacaatacctgtgtcaaacaagagaacacctgtcttcgc
aaccagtatcgctgcagcaacgggaactgtatcaacagcatttggtggtgtgactttgac
aacgactgtggagacatgagcgatgagagaaactgccctaccaccatctgtgacctggac
acccagtttcgttgccaggagtctgggacttgtatcccactgtcctataaatgtgacctt
gaggatgactgtggagacaacagtgatgaaagtcattgtgaaatgcaccagtgccggagt
gacgagtacaactgcagttccggcatgtgcatccgctcctcctgggtatgtgacggggac
aacgactgcagggactggtctgatgaagccaactgtaccgccatctatcacacctgtgag
gcctccaacttccagtgccgaaacgggcactgcatcccccagcggtgggcgtgtgacggg
gatacggactgccaggatggttccgatgaggatccagtcaactgtgagaagaagtgcaat
ggattccgctgcccaaacggcacttgcatcccatccagcaaacattgtgatggtctgcgt
gattgctctgatggctccgatgaacagcactgcgagcccctctgtacgcacttcatggac
tttgtgtgtaagaaccgccagcagtgcctgttccactccatggtctgtgacggaatcatc
cagtgccgcgacgggtccgatgaggatgcggcgtttgcaggatgctcccaagatcctgag
ttccacaaggtatgtgatgagttcggtttccagtgtcagaatggagtgtgcatcagtttg
atttggaagtgcgacgggatggatgattgcggcgattattctgatgaagccaactgcgaa
aaccccacagaagccccaaactgctcccgctacttccagtttcggtgtgagaatggccac
tgcatccccaacagatggaaatgtgacagggagaacgactgtggggactggtctgatgag
aaggattgtggagattcacatattcttcccttctcgactcctgggccctccacgtgtctg
cccaattactaccgctgcagcagtgggacctgcgtgatggacacctgggtgtgcgacggg
taccgagattgtgcagatggctctgacgaggaagcctgccccttgcttgcaaacgtcact
gctgcctccactcccacccaacttgggcgatgtgaccgatttgagttcgaatgccaccaa
ccgaagacgtgtattcccaactggaagcgctgtgacggccaccaagattgccaggatggc
cgggacgaggccaattgccccacacacagcaccttgacttgcatgagcagggagttccag
tgcgaggacggggaggcctgcattgtgctctcggagcgctgcgacggcttcctggactgc
tcggacgagagcgatgaaaaggcctgcagtgatgagttgactgtgtacaaagtacagaat
cttcagtggacagctgacttctctggggatgtgactttgacctggatgaggcccaaaaaa
atgccctctgcttcttgtgtatataatgtctactacagggtggttggagagagcatatgg
aagactctggagacccacagcaataagacaaacactgtattaaaagtcttgaaaccagat
accacgtatcaggttaaagtacaggttcagtgtctcagcaaggcacacaacaccaatgac
tttgtgaccctgaggaccccagagggattgccagatgcccctcgaaatctccagctgtca
ctccccagggaagcagaaggtgtgattgtaggccactgggctcctcccatccacacccat
ggcctcatccgtgagtacattgtagaatacagcaggagtggttccaagatgtgggcctcc
cagagggctgctagtaactttacagaaatcaagaacttattggtcaacactctatacacc
gtcagagtggctgcggtgactagtcgtggaataggaaactggagcgattctaaatccatt
accaccataaaaggaaaagtgatcccaccaccagatatccacattgacagctatggtgaa
aattatctaagcttcaccctgaccatggagagtgatatcaaggtgaatggctatgtggtg
aaccttttctgggcatttgacacccacaagcaagagaggagaactttgaacttccgagga
agcatattgtcacacaaagttggcaatctgacagctcatacatcctatgagatttctgcc
tgggccaagactgacttgggggatagccctctggcatttgagcatgttatgaccagaggg
gttcgcccacctgcacctagcctcaaggccaaagccatcaaccagactgcagtggaatgt
acctggaccggcccccggaatgtggtttatggtattttctatgccacgtcctttcttgac
ctctatcgcaacccgaagagcttgactacttcactccacaacaagacggtcattgtcagt
aaggatgagcagtatttgtttctggtccgtgtagtggtaccctaccaggggccatcctct
gactacgttgtagtgaagatgatcccggacagcaggcttccaccccgtcacctgcatgtg
gttcatacgggcaaaacctccgtggtcatcaagtgggaatcaccgtatgactctcctgac
caggacttgttgtatgcagttgcagtcaaagatctcataagaaagactgacaggagctac
aaagtaaaatcccgtaacagcactgtggaatacacccttaacaagttggagcctggcggg
aaataccacatcattgtccaactggggaacatgagcaaagattccagcataaaaattacc
acagtttcattatcagcacctgatgccttaaaaatcataacagaaaatgatcatgttctt
ctgttttggaaaagcctggctttaaaggaaaagcattttaatgaaagcaggggctatgag
atacacatgtttgatagtgccatgaatatcacagcttaccttgggaatactactgacaat
ttctttaaaatttccaacctgaagatgggtcataattacacgttcaccgtccaagcaaga
tgcctttttggcaaccagatctgtggggagcctgccatcctgctgtacgatgagctgggg
tctggtgcagatgcatctgcaacgcaggctgccagatctacggatgttgctgctgtggtg
gtgcccatcttattcctgatactgctgagcctgggggtggggtttgccatcctgtacacg
aagcaccggaggctgcagagcagcttcaccgccttcgccaacagccactacagctccagg
ctggggtccgcaatcttctcctctggggatgacctgggggaagatgatgaagatgcccct
atgataactggattttcagatgacgtccccatggtgatagcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
3D Structure (7)   
   PDB (7)   
Protein domain (8)   
   Pfam (8)   
All databases (91)   

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