KEGG T01001: 6675

Homo sapiens (human): 6675

Entry

6675              CDS       T01001

Symbol

UAP1, AGX, AGX1, AGX2, SPAG2

Name

(RefSeq) UDP-N-acetylglucosamine pyrophosphorylase 1

K00972

UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83]

Organism

hsa Homo sapiens (human)

Pathway

hsa00520

Amino sugar and nucleotide sugar metabolism

hsa01100

Metabolic pathways

hsa01250

Biosynthesis of nucleotide sugars

Module

hsa_M00892

UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    6675 (UAP1)
Enzymes [BR:hsa01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.23  UDP-N-acetylglucosamine diphosphorylase
     6675 (UAP1)
    2.7.7.83  UDP-N-acetylgalactosamine diphosphorylase
     6675 (UAP1)

SSDB

Motif

Pfam:

UDPGP NTP_transf_3

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

Position

1:162561531..162601240

AA seq 522 aa
MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS
HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY
PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK
HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME
QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ
VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY
VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT
ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ
CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI

NT seq 1569 nt +upstreamnt +downstreamnt
atgaacattaatgacctcaaactcacgttgtccaaagctgggcaagagcacctactacgt
ttctggaatgagcttgaagaagcccaacaggtagaactttatgcagagctccaggccatg
aactttgaggagctgaacttctttttccaaaaggccattgaaggttttaaccagtcttct
caccaaaagaatgtggatgcacgaatggaacctgtgcctcgagaggtattaggcagtgct
acaagggatcaagatcagctccaggcctgggaaagtgaaggacttttccagatttctcag
aataaagtagcagttcttcttctagctggtgggcaggggacaagactcggcgttgcatat
cctaaggggatgtatgatgttggtttgccatcccgtaagacactttttcagattcaagca
gagcgtatcctgaagctacagcaggttgctgaaaaatattatggcaacaaatgcattatt
ccatggtatataatgaccagtggcagaacaatggaatctacaaaggagttcttcaccaag
cacaagtactttggtttaaaaaaagagaatgtaatcttttttcagcaaggaatgctcccc
gccatgagttttgatgggaaaattattttggaagagaagaacaaagtttctatggctcca
gatgggaatggtggtctttatcgggcacttgcagcccagaatattgtggaggatatggag
caaagaggcatttggagcattcatgtctattgtgttgacaacatattagtaaaagtggca
gacccacggttcattggattttgcattcagaaaggagcagactgtggagcaaaggtggta
gagaaaacgaaccctacagaaccagttggagtggtttgccgagtggatggagtttaccag
gtggtagaatatagtgagatttccctggcaacagctcaaaaacgaagctcagacggacga
ctgctgttcaatgcggggaacattgccaaccatttcttcactgtaccatttctgagagat
gttgtcaatgtttatgaacctcagttgcagcaccatgtggctcaaaagaagattccttat
gtggatacccaaggacagttaattaagccagacaaacccaatggaataaagatggaaaaa
tttgtctttgacatcttccagtttgcaaagaagtttgtggtatatgaagtattgcgagaa
gatgagttttccccactaaagaatgctgatagtcagaatgggaaagacaaccctactact
gcaaggcatgctttgatgtcccttcatcattgctgggtcctcaatgcagggggccatttc
atagatgaaaatggctctcgccttccagcaattccccgcagtgctacaaatgggaagtca
gagaccatcacagctgatgtcaatcacaacttgaaggatgccaatgatgtaccaatccaa
tgtgaaatctctcctcttatctcctatgctggagaaggattagaaagttatgtggcagat
aaagaattccatgcacctctaatcatcgatgagaatggagttcatgagctggtgaaaaat
ggtatttga

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