KEGG   Homo sapiens (human): 6721
Entry
6721              CDS       T01001                                 
Symbol
SREBF2, SREBP-2, SREBP2, bHLHd2
Name
(RefSeq) sterol regulatory element binding transcription factor 2
  KO
K09107  sterol regulatory element-binding transcription factor 2
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    6721 (SREBF2)
   04131 Membrane trafficking [BR:hsa04131]
    6721 (SREBF2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    6721 (SREBF2)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Others
   Others
    6721 (SREBF2)
SSDB
Motif
Pfam: HLH
Other DBs
NCBI-GeneID: 6721
NCBI-ProteinID: NP_004590
OMIM: 600481
HGNC: 11290
Ensembl: ENSG00000198911
UniProt: Q12772
Structure
Position
22:41833105..41907305
AA seq 1141 aa
MDDSGELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGSGGS
GSSSGSSGSSSSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQAPTLQVKVSPTS
VPTTPRATPILQPRPQPQPQPQTQLQQQTVMITPTFSTTPQTRIIQQPLIYQNAATSFQV
LQPQVQSLVTSSQVQPVTIQQQVQTVQAQRVLTQTANGTLQTLAPATVQTVAAPQVQQVP
VLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTTPIQTAALQVPTLVGSSGTILT
TMPVMMGQEKVPIKQVPGGVKQLEPPKEGERRTTHNIIEKRYRSSINDKIIELKDLVMGT
DAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDNEVDLK
IEDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRS
RILLCVLTFLCLSFNPLTSLLQWGGAHDSDQHPHSGSGRSVLSFESGSGGWFDWMMPTLL
LWLVNGVIVLSVFVKLLVHGEPVIRPHSRSSVTFWRHRKQADLDLARGDFAAAAGNLQTC
LAVLGRALPTSRLDLACSLSWNVIRYSLQKLRLVRWLLKKVFQCRRATPATEAGFEDEAK
TSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNLAECAEEKIPPSTLVEIHLTA
AMGLKTRCGGKLGFLASYFLSRAQSLCGPEHSAVPDSLRWLCHPLGQKFFMERSWSVKSA
AKESLYCAQRNPADPIAQVHQAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEY
LKLLHSFVDSVGVMSPPLSRSSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFT
KVERIPKALEVTESPLVKAIFHACRAMHASLPGKADGQQSSFCHCERASGHLWSSLNVSG
ATSDPALNHVVQLLTCDLLLSLRTALWQKQASASQAVGETYHASGAELAGFQRDLGSLRR
LAHSFRPAYRKVFLHEATVRLMAGASPTRTHQLLEHSLRRRTTQSTKHGEVDAWPGQRER
ATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRRSCNDCQQMIVKLGGGTAIAA
S
NT seq 3426 nt   +upstreamnt  +downstreamnt
atggacgacagcggcgagctgggtggtctggagaccatggagaccctcacggagctgggc
gacgagctgaccctgggagacatcgacgagatgctgcaatttgtcagtaatcaagtggga
gagttccctgacttgttttcagaacagctgtgtagctcctttcctggcagtggtggtagt
ggtagcagcagcggcagcagtggcagcagcagcagcagcagcaatggcaggggcagcagc
agcggagctgtggacccttcagtgcaacggtcattcacccaggtcacattaccttccttc
tctccctcggcggcctccccacaggctccaactctgcaagtcaaggtttctcccacctca
gttcccaccacacccagggcaactcctattcttcagccccgcccccagccccagcctcaa
cctcaaactcagctgcaacaacagacggtaatgatcacgccaacattcagcaccactccg
cagacgaggatcatccagcagcctttgatataccagaatgcagctactagctttcaagtc
cttcagcctcaagtccaaagcctggtgacatcctcccaggtacagccggtcaccattcag
cagcaggtgcagacagtacaggcccagcgggtgctgacacaaacggccaatggcacgctg
cagacccttgccccggctacggtgcagacagttgctgcgccacaggtgcagcaggtcccg
gtcctggtccagcctcagatcatcaagacagattcccttgttttgaccacactgaagaca
gatggcagccctgttatggctgcggtccagaacccggccctcaccgccctcaccacccct
atccagacggctgcccttcaagtaccaaccctggtgggcagcagtgggaccattctgacc
acaatgcctgtaatgatggggcaagagaaagtgcccattaagcaggtacctgggggagtc
aagcagcttgagccccccaaagaaggagaaaggcggacaacccataatatcattgagaaa
cgatatcgctcctccatcaatgacaaaatcatcgaattgaaagacctggtcatggggaca
gacgccaagatgcacaagtctggcgttctgaggaaggccattgattacatcaaatacttg
cagcaggtcaatcataaactgcgccaggagaacatggtgctgaagctggcaaatcaaaag
aacaagcttctaaagggcatcgacctaggcagtctggtggacaatgaggtggacctgaag
atcgaggactttaatcagaatgtccttctgatgtcccccccagcctctgactcagggtcc
caggctggcttctctccctactccattgactctgagccaggaagccctctattggatgat
gcaaaggtcaaagatgagccagactctcctcctgtggcgctgggcatggtagaccgctca
cggattcttctgtgtgtcctcaccttcctgtgcctctcctttaaccccctgacttccctg
ctgcagtggggaggggcccacgactctgaccagcacccacactcaggctctggccgcagt
gtcctgtcattcgagtcaggttctgggggctggtttgactggatgatgcctactcttctc
ttatggctggtaaatggtgtgattgtcctgagcgtctttgtgaagctgctggttcatggg
gagccagtgatccggccacactcgcgctcctcggtcaccttctggaggcaccggaaacag
gcagatctggatctcgccagaggagattttgcagctgctgccggcaacctacaaacctgc
ctggcagttttgggccgggcactgcccacctcccgcctggacctggcctgcagcctctcc
tggaacgtgatccgctacagcctgcagaagctacgcctggtgcgctggctgctcaagaaa
gtcttccagtgccggcgggccacgccagccactgaggcaggctttgaagacgaagctaag
accagcgcccgggatgcggctctggcctatcaccggctgcaccagctgcacatcacaggg
aagcttcctgcaggatccgcctgttccgatgtacacatggcgttgtgtgccgtgaacctg
gctgaatgtgcagaggagaagatcccaccgagcacactggttgagatccatctgactgct
gccatggggctcaagacccggtgtggaggcaagctgggcttcctggccagctacttcctc
agccgagcccagagcctgtgtggccccgagcacagtgctgttcctgactccctgcgctgg
ctctgccaccccctgggccagaagtttttcatggagcggagctggtctgtgaagtcagct
gccaaggagagtctatactgtgcccagaggaacccagctgaccccattgcgcaggtccac
caggccttctgcaagaacctgctggagcgagctatagagtccttggtgaaacctcaggcc
aagaagaaggctggagaccaggaagaagagagctgtgaattctccagtgctctggagtac
ttgaaattacttcattcttttgtggactctgtgggggttatgagccccccactctccagg
agctccgtgctcaagtccgccctgggtccagacatcatctgtcggtggtggacgtctgca
atcactgtggccatcagctggctccagggagacgatgcagctgtgcgctctcattttacc
aaagtggaacgcatccccaaggccctggaagtgacagagagccccctggtgaaggccatc
ttccatgcctgcagagccatgcatgcctcactccctgggaaagcagatgggcagcagagt
tccttctgccattgcgagagggccagtggccacctatggagcagcctcaacgtcagtggg
gccacctctgaccctgccctcaaccacgtggtccagctgctcacctgtgacctgctactg
tcgctacggacagcgctctggcaaaaacaggccagtgccagccaggctgtgggggagacc
taccacgcgtcaggcgctgaactggcgggcttccaacgggacctgggcagcctgcgcagg
ctggcacacagcttccgcccagcataccgcaaggtgttcctgcatgaagccaccgtgcgc
ctgatggcaggagccagccccacccgcacccaccagctgctggaacacagcctgcggcgg
cgcaccacgcagagcaccaagcacggagaggtggatgcctggcccggccagcgagagcgg
gccaccgccatcctgctggcctgccgccacctgcccctctccttcctctcctccccgggc
cagcgggcagtgctgctggccgaagctgcccgcaccctggagaaggtgggcgaccggcgc
tcctgcaacgactgccagcagatgattgttaagctgggtggtggcactgccattgccgcc
tcctga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (28)   
   RefSeq(nuc) (12)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (71)   

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