KEGG   Homo sapiens (human): 6898
Entry
6898              CDS       T01001                                 
Symbol
TAT
Name
(RefSeq) tyrosine aminotransferase
  KO
K00815  tyrosine aminotransferase [EC:2.6.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00130  Ubiquinone and other terpenoid-quinone biosynthesis
hsa00270  Cysteine and methionine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00400  Phenylalanine, tyrosine and tryptophan biosynthesis
hsa01100  Metabolic pathways
Module
hsa_M00034  Methionine salvage pathway
hsa_M00044  Tyrosine degradation, tyrosine => homogentisate
Network
nt06016  Phenylalanine and tyrosine metabolism
  Element
N00708  Tyrosine degradation
Disease
H00165  Tyrosinemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    6898 (TAT)
   00350 Tyrosine metabolism
    6898 (TAT)
   00360 Phenylalanine metabolism
    6898 (TAT)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    6898 (TAT)
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    6898 (TAT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    6898 (TAT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.5  tyrosine transaminase
     6898 (TAT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   6898 (TAT)
SSDB
Motif
Pfam: Aminotran_1_2 TAT_ubiq Aminotran_5 Cys_Met_Meta_PP DegT_DnrJ_EryC1 Beta_elim_lyase Asp_aminotransf
Other DBs
NCBI-GeneID: 6898
NCBI-ProteinID: NP_000344
OMIM: 613018
HGNC: 11573
Ensembl: ENSG00000198650
UniProt: P17735 A0A140VKB7
Structure
Position
16:complement(71565660..71577092)
AA seq 454 aa
MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIV
DNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSRE
EIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG
IEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQ
CVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDI
FGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAI
PGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVI
TVPEVMMLEACSRIQEFCEQHYHCAEGSQEECDK
NT seq 1365 nt   +upstreamnt  +downstreamnt
atggacccatacatgattcagatgagcagcaaaggcaacctcccctcaattctggacgtg
catgtcaacgttggtgggagaagctctgtgccgggaaaaatgaaaggcagaaaggccagg
tggtctgtgaggccctcagacatggccaagaaaactttcaaccccatccgagccattgtg
gacaacatgaaggtgaaaccaaatccaaacaaaaccatgatttccctgtccattggggac
cctactgtgtttggaaacctgcctacagaccctgaagttacccaggcaatgaaagatgcc
ctggactcgggcaaatataatggctatgccccatccatcggcttcctatccagtcgggag
gagattgcttcttattaccactgtcctgaggcacccctagaagctaaggacgtcattctg
acaagtggctgcagccaagctattgacctttgtttagctgtgttggccaacccagggcaa
aacatcctggttccaagacctggtttctctctctacaagactctggctgagtctatggga
attgaggtcaaactctacaatttgttgccagagaaatcttgggaaattgacctgaaacaa
ctggaatatctaattgatgaaaagacagcttgtctcattgtcaataatccatcaaacccc
tgtgggtcagtgttcagcaaacgtcatcttcagaagattctggcagtggctgcacggcag
tgtgtccccatcttagctgatgagatctatggagacatggtgttttcggattgcaaatat
gaaccactggccaccctcagcaccgatgtccccatcctgtcctgtggagggctggccaag
cgctggctggttcctggctggaggttgggctggatcctcattcatgaccgaagagacatt
tttggcaatgagatccgagatgggctggtgaagctgagtcagcgcattttgggaccctgt
accattgtccagggagctctgaaaagcatcctatgtcgcaccccgggagagttttaccac
aacactctgagcttcctcaagtccaatgctgatctctgttatggggcgttggctgccatc
cctggactccggccagtccgcccttctggggctatgtacctcatggttggaattgagatg
gaacatttcccagaatttgagaacgatgtggagttcacggagcggttagttgctgagcag
tctgtccactgcctcccagcaacgtgctttgagtacccgaatttcatccgagtggtcatc
acagtccccgaggtgatgatgctggaggcgtgcagccggatccaggagttctgtgagcag
cactaccattgtgctgaaggcagccaggaggagtgtgataaatag

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