KEGG   Homo sapiens (human): 6908
Entry
6908              CDS       T01001                                 
Symbol
TBP, GTF2D, GTF2D1, HDL4, SCA17, TBP1, TFIID
Name
(RefSeq) TATA-box binding protein
  KO
K03120  transcription initiation factor TFIID TATA-box-binding protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03022  Basal transcription factors
hsa05016  Huntington disease
hsa05017  Spinocerebellar ataxia
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Network
nt06166  Human papillomavirus (HPV)
  Element
N00376  HPV E7 to TBP1-mediated transcription
Disease
H00063  Spinocerebellar ataxia (SCA)
H01243  Huntington disease-like syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    6908 (TBP)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    6908 (TBP)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    6908 (TBP)
   05165 Human papillomavirus infection
    6908 (TBP)
  09164 Neurodegenerative disease
   05016 Huntington disease
    6908 (TBP)
   05017 Spinocerebellar ataxia
    6908 (TBP)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    6908 (TBP)
   03021 Transcription machinery [BR:hsa03021]
    6908 (TBP)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   TATA-binding proteins
    6908 (TBP)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIID
     6908 (TBP)
  RNA polymerase III system
    TFIIIB
     6908 (TBP)
  RNA polymerase I system
    SL1/TIF-1B
     6908 (TBP)
SSDB
Motif
Pfam: TBP DDHD EPL1 Peptidase_S64 TFIIA DUF4746 TMEM51 Tra1_central Cellulose_synt PAT1 MDM10 DUF1501 Tim54 Presenilin SpoIIP FemAB
Other DBs
NCBI-GeneID: 6908
NCBI-ProteinID: NP_003185
OMIM: 600075
HGNC: 11588
Ensembl: ENSG00000112592
UniProt: P20226 Q32MN7
Structure
Position
6:170554369..170572859
AA seq 339 aa
MDQNNSLPPYAQGLASPQGAMTPGIPIFSPMMPYGTGLTPQPIQNTNSLSILEEQQRQQQ
QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQAPQ
LFHSQTLTTAPLPGTTPLYPSPMTPMTPITPATPASESSGIVPQLQNIVSTVNLGCKLDL
KTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV
VQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRI
VLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKTT
NT seq 1020 nt   +upstreamnt  +downstreamnt
atggatcagaacaacagcctgccaccttacgctcagggcttggcctcccctcagggtgcc
atgactcccggaatccctatctttagtccaatgatgccttatggcactggactgacccca
cagcctattcagaacaccaatagtctgtctattttggaagagcaacaaaggcagcagcag
caacaacaacagcagcagcagcagcagcagcagcaacagcaacagcagcagcagcagcag
cagcagcagcagcagcagcagcagcagcagcagcagcagcaacaggcagtggcagctgca
gccgttcagcagtcaacgtcccagcaggcaacacagggaacctcaggccaggcaccacag
ctcttccactcacagactctcacaactgcacccttgccgggcaccactccactgtatccc
tcccccatgactcccatgacccccatcactcctgccacgccagcttcggagagttctggg
attgtaccgcagctgcaaaatattgtatccacagtgaatcttggttgtaaacttgaccta
aagaccattgcacttcgtgcccgaaacgccgaatataatcccaagcggtttgctgcggta
atcatgaggataagagagccacgaaccacggcactgattttcagttctgggaaaatggtg
tgcacaggagccaagagtgaagaacagtccagactggcagcaagaaaatatgctagagtt
gtacagaagttgggttttccagctaagttcttggacttcaagattcagaatatggtgggg
agctgtgatgtgaagtttcctataaggttagaaggccttgtgctcacccaccaacaattt
agtagttatgagccagagttatttcctggtttaatctacagaatgatcaaacccagaatt
gttctccttatttttgtttctggaaaagttgtattaacaggtgctaaagtcagagcagaa
atttatgaagcatttgaaaacatctaccctattctaaagggattcaggaagacgacgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Network (2)   
   KEGG NETWORK (2)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
3D Structure (65)   
   PDB (65)   
Protein domain (16)   
   Pfam (16)   
All databases (158)   

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