KEGG   Homo sapiens (human): 7083
Entry
7083              CDS       T01001                                 
Symbol
TK1, TK2
Name
(RefSeq) thymidine kinase 1
  KO
K00857  thymidine kinase [EC:2.7.1.21]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00240  Pyrimidine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    7083 (TK1)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    7083 (TK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.21  thymidine kinase
     7083 (TK1)
SSDB
Motif
Pfam: TK AAA_14 ATPase_2
Other DBs
NCBI-GeneID: 7083
NCBI-ProteinID: NP_003249
OMIM: 188300
HGNC: 11830
Ensembl: ENSG00000167900
UniProt: P04183 A0A384MDV9
Structure
Position
17:complement(78174079..78187204)
AA seq 234 aa
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
NT seq 705 nt   +upstreamnt  +downstreamnt
atgagctgcattaacctgcccactgtgctgcctggctcccccagcaagacccgggggcag
atccaggtgattctcgggccgatgttctcaggaaaaagcacagagttgatgagacgcgtc
cgtcgcttccagattgctcagtacaagtgcctggtgatcaagtatgccaaagacactcgc
tacagcagcagcttctgcacacatgaccggaacaccatggaggcactgcccgcctgcctg
ctccgagacgtggcccaggaggccctgggcgtggctgtcataggcatcgacgaggggcag
tttttccctgacatcgtggagttctgcgaggccatggccaacgccgggaagaccgtaatt
gtggctgcactggatgggaccttccagaggaagccatttggggccatcctgaacctggtg
ccgctggccgagagcgtggtgaagctgacggcggtgtgcatggagtgcttccgggaagcc
gcctataccaagaggctcggcacagagaaggaggtcgaggtgattgggggagcagacaag
taccactccgtgtgtcggctctgctacttcaagaaggcctcaggccagcctgccgggccg
gacaacaaagagaactgcccagtgccaggaaagccaggggaagccgtggctgccaggaag
ctctttgccccacagcagattctgcaatgcagccctgccaactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (14)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (27)   
   RefSeq(nuc) (3)   
   GenBank (12)   
   EMBL (12)   
3D Structure (4)   
   PDB (4)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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