KEGG   Homo sapiens (human): 7175
Entry
7175              CDS       T01001                                 
Symbol
TPR, MRT79
Name
(RefSeq) translocated promoter region, nuclear basket protein
  KO
K09291  nucleoprotein TPR
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05014  Amyotrophic lateral sclerosis
hsa05200  Pathways in cancer
hsa05216  Thyroid cancer
Disease
H00032  Thyroid cancer
H00768  Autosomal recessive intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    7175 (TPR)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    7175 (TPR)
  09162 Cancer: specific types
   05216 Thyroid cancer
    7175 (TPR)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    7175 (TPR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    7175 (TPR)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Nuclear pore complex
     7175 (TPR)
SSDB
Motif
Pfam: TPR_MLP1_2 Seryl_tRNA_N DUF5082 DUF1192 Imm70
Other DBs
NCBI-GeneID: 7175
NCBI-ProteinID: NP_003283
OMIM: 189940
HGNC: 12017
Ensembl: ENSG00000047410
UniProt: P12270
Structure
Position
1:complement(186311652..186375253)
AA seq 2363 aa
MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKR
LSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEEL
EAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE
KRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQM
NGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS
NELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLL
SATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRIN
KYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSS
VLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSY
RNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQ
MQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVI
ESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDF
ASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVR
AENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQ
IEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKE
IATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTS
NVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD
DKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQN
KYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKD
EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEIL
RFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHE
ELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGM
LQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKA
EIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRR
YKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENL
QKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAA
KSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREH
QERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGERGIASTSDPPTANIKPTPVVSTPSK
VTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVEHVPV
FGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSNIVEV
VQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDDTVEMPLPKKLK
SVTPVGTEEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDL
GPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTG
MGDEGEDSNEGTGSADGNDGYEADDAEGGDGTDPGTETEESMGGGEGNHRAADSQNSGEG
NTGAAESSFSQEVSREQQPSSASERQAPRAPQSPRRPPHPLPPRLTIHAPPQELGPPVQR
IQMTRRQSVGRGLQLTPGIGGMQQHFFDDEDRTVPSTPTLVVPHRTDGFAEAIHSPQVAG
VPRFRFGPPEDMPQTSSSHSDLGQLASQGGLGMYETPLFLAHEEESGGRSVPTTPLQVAA
PVTVFTESTTSDASEHASQSVPMVTTSTGTLSTTNETATGDDGDEVFVEAESEGISSEAG
LEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRRVRLQTTLRQGVRGRQ
FNRQRGVSHAMGGRGGINRGNIN
NT seq 7092 nt   +upstreamnt  +downstreamnt
atggcggcggtgttgcagcaagtcctggagcgcacggagctgaacaagctgcccaagtct
gtccagaacaaacttgaaaagttccttgctgatcagcaatccgagatcgatggcctgaag
gggcggcatgagaaatttaaggtggagagcgaacaacagtattttgaaatagaaaagagg
ttgtcccacagtcaggagagacttgtgaatgaaacccgagagtgtcaaagcttgcggctt
gagctagagaaactcaacaatcaactgaaggcactaactgagaaaaacaaagaacttgaa
attgctcaggatcgcaatattgccattcagagccaatttacaagaacaaaggaagaatta
gaagctgagaaaagagacttaattagaaccaatgagagactatctcaagaacttgaatac
ttaacagaggatgttaaacgtctgaatgaaaaacttaaagaaagcaatacaacaaagggt
gaacttcagttaaaattggatgaacttcaagcttctgatgtttctgttaagtatcgagaa
aaacgcttggagcaagaaaaggaattgctacatagtcagaatacatggctgaatacagag
ttgaaaaccaaaactgatgaacttctggctcttggaagagaaaaagggaatgagattcta
gagcttaaatgtaatcttgaaaataaaaaagaagaggtttctagactggaagaacaaatg
aatggcttaaaaacatcaaatgaacatcttcaaaagcatgtggaggatctgttgaccaaa
ttaaaagaggccaaggaacaacaggccagtatggaagagaaattccacaatgaattaaat
gcccacataaaactttctaatttgtacaagagtgccgctgatgactcagaagcaaagagc
aatgaactaacccgggcagtagaggaactacacaaacttttgaaagaagctggtgaagcc
aacaaagcaatacaagatcatcttctagaggtggagcaatccaaagatcaaatggaaaaa
gaaatgcttgagaaaatagggagattggagaaggaattagagaatgcaaatgaccttctt
tctgccacaaaacgtaaaggagccatattgtctgaagaagagcttgccgccatgtctcct
actgcagcagctgtagctaagatagtgaaacctgggatgaaactaactgagctctataat
gcttatgtggaaactcaggatcagttgcttttggagaaactagagaacaaaagaattaat
aagtacctagatgaaatagtgaaagaagtggaagccaaagcaccaattttgaaacgccag
cgtgaggaatatgaacgtgcacagaaagctgtagcaagtttatctgttaagcttgaacaa
gctatgaaggagattcagcgattgcaggaggacactgataaagccaacaagcaatcatct
gtacttgagagagataatcgaagaatggaaatacaagtaaaagatctttcacaacagatt
agagtgcttttgatggaacttgaagaagcaaggggtaaccacgtaattcgtgatgaggaa
gtaagctctgctgatataagtagttcatctgaggtaatatcacagcatctagtatcttac
agaaatattgaagagcttcaacaacaaaatcaacgtctcttagtggcccttagagagctt
ggggaaaccagagaaagagaagaacaagaaacaacttcatccaaaatcactgagcttcag
ctcaaacttgagagtgcccttactgaactagaacaactccgcaaatcacgacagcatcaa
atgcagcttgttgattccatagttcgtcagcgtgatatgtaccgtattttattgtcacaa
acaacaggagttgccattccattacatgcttcaagcttagatgatgtttctcttgcatca
actccaaaacgtccaagtacatcacagactgtttccactcctgctccagtacctgttatt
gaatcaacagaggctatagaggctaaggctgcccttaaacagttgcaggaaatttttgag
aactacaaaaaagaaaaagcagaaaatgaaaaaatacaaaatgagcagcttgagaaactt
caagaacaagttacagatttgcgatcacaaaataccaaaatttctacccagctagatttt
gcttctaaacgttatgaaatgctgcaagataatgttgaaggatatcgtcgagaaataaca
tcacttcatgagagaaatcagaaactcactgccacaactcaaaagcaagaacagattatc
aatacgatgactcaagatttgagaggagcaaatgagaagctagctgtcgcagaagtaaga
gcagaaaatttgaagaaggaaaaggaaatgcttaaattgtctgaagttcgtctttctcag
caaagagagtctttgttagctgaacaaagggggcaaaacttactgctaactaatctgcaa
acaattcagggaatactggagcgatctgaaacagaaaccaaacaaaggcttagtagccag
atagaaaaactggaacatgagatctctcatctaaagaagaagttggaaaatgaggtggaa
caaaggcatacacttactagaaatctagatgttcaacttttagatacaaagagacaactg
gatacagagacaaatcttcatcttaacacaaaagaactattaaaaaatgctcaaaaagaa
attgccacattgaaacagcacctcagtaatatggaagtccaagttgcttctcagtcttca
cagagaactggtaaaggtcagcctagcaacaaagaagatgtggatgatcttgtgagtcag
ctaagacagacagaagagcaggtgaatgacttaaaggagagactcaaaacaagtacgagc
aatgtggaacaatatcaagcaatggttactagtttagaagaatccctgaacaaggaaaaa
caggtgacagaagaagtgcgtaagaatattgaagttcgtttaaaagagtcagctgaattt
cagacacagttggaaaagaagttgatggaagtagagaaggaaaaacaagaacttcaggat
gataaaagaagagccatagagagcatggaacaacagttatctgaattgaagaaaacactt
tctagtgttcagaatgaagtacaagaagctcttcagagagcaagcacagctttaagtaat
gagcagcaagccagacgtgactgtcaggaacaagctaaaatagctgtggaagctcagaat
aagtatgagagagaattgatgctgcatgctgctgatgttgaagctctacaagctgcgaag
gagcaggtttcaaaaatggcatcagtccgtcagcatttggaagaaacaacacagaaagca
gaatcacagttgttggagtgtaaagcatcttgggaggaaagagagagaatgttaaaggat
gaagtttccaaatgtgtatgtcgctgtgaagatctggagaaacaaaacagattacttcat
gatcagatcgaaaaattaagtgacaaggtcgttgcctctgtgaaggaaggtgtacaaggt
ccactgaatgtatctctcagtgaagaaggaaaatctcaagaacaaattttggaaattctc
agatttatacgacgagaaaaagaaattgctgaaactaggtttgaggtggctcaggttgag
agtctgcgttatcgacaaagggttgaacttttagaaagagagctgcaggaactgcaagat
agtctaaatgctgaaagggagaaagtccaggtaactgcaaaaacaatggctcagcatgaa
gaactgatgaagaaaactgaaacaatgaatgtagttatggagaccaataaaatgctaaga
gaagagaaggagagactagaacaggatctacagcaaatgcaagcaaaggtgaggaaactg
gagttagatattttacccttacaagaagcaaatgctgagctgagtgagaaaagcggtatg
ttgcaggcagagaagaagctcttagaagaggatgtcaaacgttggaaagcacgtaaccag
catctagtaagtcaacagaaagatccagatacagaagaatatcggaagctcctttctgaa
aaggaagttcatactaagcgtattcaacaattgacagaagaaattggtagacttaaagct
gaaattgcaagatcaaatgcatctttgactaacaaccagaacttaattcagagtctgaag
gaagatctaaataaagtaagaactgaaaaggaaaccatccagaaggacttagatgccaaa
ataattgatatccaagaaaaagtcaaaactattactcaagttaagaaaattggacgtagg
tacaagactcaatatgaagaacttaaagcacaacaggataaggttatggagacatcggct
cagtcctctggagaccatcaggagcagcatgtttcagtccaggaaatgcaggaactcaaa
gaaacgctcaaccaagctgaaacaaaatcaaaatcacttgaaagtcaagtagagaatctg
cagaagacattatctgaaaaagagacagaagcaagaaatctccaggaacagactgtgcaa
cttcagtctgaactttcacgacttcgtcaggatcttcaagatagaaccacacaggaggag
cagctccgacaacagataactgaaaaggaagaaaaaaccagaaaggctattgtagcagca
aagtcaaaaattgcacacttagctggtgtaaaagatcagctaactaaagaaaatgaggag
cttaaacaaaggaatggagccttagatcagcagaaagatgaattggatgttcgcattact
gcgctaaagtcccaatatgaaggtcgaattagtcgcttggaaagagaactcagggagcat
caagagagacaccttgagcagagagatgagcctcaagaaccttctaataaggtccctgaa
cagcagagacagatcacattgaaaacaactccagcttctggtgaaagaggaattgccagc
acatcagacccaccaacagccaatatcaagccaactcctgttgtgtctactccaagtaaa
gtgacagctgcagctatggctggaaataagtcaacacccagggctagtatccgcccaatg
gttacacctgcaactgttacaaatcccactactaccccaacagctacagtgatgcccact
acacaagtggaatcacaggaagctatgcagtcagaagggcctgtggaacatgttccagtt
tttggaagcacaagtggatccgttcgttctactagtcctaatgtccagccttctatctct
caacctattttaactgttcagcaacaaacacaggctacagcttttgtgcaacccactcaa
cagagtcatcctcagattgagcctgccaatcaagagttatcttcaaacatagtagaggtt
gttcagagttcaccagttgagcggccttctacttccacagcagtatttggcacagtttcg
gctacccccagttcttctttgccaaagcgtacacgtgaagaggaagaggatagcaccata
gaagcatcagaccaagtctctgatgatacagtggaaatgcctcttccaaagaagttgaaa
agtgtcacacctgtaggaactgaggaagaagttatggcagaagaaagtactgatggagag
gtagagactcaggtatacaaccaggattctcaagattccattggagaaggagttacccag
ggagattatacacctatggaagacagtgaagaaacctctcagtctctacaaatagatctt
gggccacttcaatcagatcagcagacgacaacttcatcccaggatggtcaaggcaaagga
gatgatgtcattgtaattgacagtgatgatgaagaagaggatgatgatgaaaatgatgga
gaacatgaggattatgaagaggatgaggaagatgatgatgatgatgaagatgacacaggg
atgggagatgagggtgaagatagtaatgaaggaactggtagtgccgatggcaatgatggt
tatgaagctgatgatgctgagggtggtgatgggactgatccaggtacagaaacagaagaa
agtatgggtggaggtgaaggtaatcacagagctgctgattctcaaaacagtggtgaagga
aatacaggtgctgcagaatcttctttttctcaggaggtttctagagaacaacagccatca
tcagcatctgaaagacaggcccctcgagcacctcagtcaccgagacgcccaccacatcca
cttcccccaagactgaccattcatgccccacctcaggagttgggaccaccagttcagaga
attcagatgacccgaaggcagtctgtaggacgtggccttcagttgactccaggaataggt
ggcatgcaacagcatttttttgatgatgaagacagaacagttccaagtactccaactctt
gtggtgccacatcgtactgatggatttgctgaagcaattcattcgccgcaggttgctggt
gtccctagattccggtttgggccacctgaagatatgccacaaacaagttctagtcactct
gatcttggccagcttgcttctcaaggaggtttaggaatgtatgaaacacccctgttccta
gctcatgaagaagagtcaggtggccgaagtgttcccactactccactacaagtagcagcc
ccagtgactgtatttactgagagcaccacctctgatgcttcggaacatgcctctcaatct
gttccaatggtgactacatccactggcactttatctacaacaaatgaaacagcaacaggt
gatgatggagatgaagtatttgtggaggcagaatctgaaggtattagttcagaagcaggc
ctagaaattgatagccagcaggaagaagagccggttcaagcatctgatgagtcagatctc
ccctccaccagccaggatcctccttctagctcatctgtagatactagtagtagtcaacca
aagcctttcagacgagtaagacttcagacaacattgagacaaggtgtccgtggtcgtcag
tttaacagacagagaggtgtgagccatgcaatgggagggagaggaggaataaacagagga
aatattaattaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (4)   
   PDB (4)   
Protein domain (5)   
   Pfam (5)   
All databases (83)   

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