KEGG   Homo sapiens (human): 7224
Entry
7224              CDS       T01001                                 
Symbol
TRPC5, PPP1R159, TRP5
Name
(RefSeq) transient receptor potential cation channel subfamily C member 5
  KO
K04968  transient receptor potential cation channel subfamily C member 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04929  GnRH secretion
Drug target
Clemizole (DG02846): D01705 D02013
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    7224 (TRPC5)
  09158 Development and regeneration
   04360 Axon guidance
    7224 (TRPC5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    7224 (TRPC5)
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7224 (TRPC5)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     7224 (TRPC5)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7224 (TRPC5)
SSDB
Motif
Pfam: Ion_trans TRP_2 Ank_2 Ank Ank_3 Ank_4 PKD_channel
Other DBs
NCBI-GeneID: 7224
NCBI-ProteinID: NP_036603
OMIM: 300334
HGNC: 12337
Ensembl: ENSG00000072315
UniProt: Q9UL62
Structure
Position
X:complement(111768011..112082776)
AA seq 973 aa
MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYN
VNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRR
PSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVE
CVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAE
YEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKE
FVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFI
KKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIK
EMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEA
LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF
YYETRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFV
GATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPP
FNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNL
VKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRKHPRSFSTSSTELSQR
DDNNDGSGGARAKSKSVSFNLGCKKKTCHGPPLIRTMPRSSGAQGKSKAESSSKRSFMGP
SLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQMEKGKAEACSQSEIN
LSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETWGEACDLLMHK
WGDGQEEQVTTRL
NT seq 2922 nt   +upstreamnt  +downstreamnt
atggcccaactgtactacaaaaaggtcaactactcaccgtacagagaccgcatccccctg
caaattgtgagggctgagacagagctctctgcagaggagaaggccttcctcaatgctgtg
gagaagggggactatgccactgtgaagcaggcccttcaggaggctgagatctactataat
gttaacatcaactgcatggaccccttgggccggagtgccctgctcattgccattgagaac
gagaacctggagatcatggagctactgctgaaccacagcgtgtatgtgggtgatgcattg
ctctatgccatacgcaaggaagtggtgggcgctgtggagcttctgctcagctacaggcgg
cccagcggagagaagcaggtccccactctgatgatggacacgcagttctctgaattcaca
ccggacatcactcccatcatgctggctgcccacaccaacaactacgaaatcatcaaattg
cttgtccaaaaacgggtcactatcccacggccccaccagatccgctgcaactgtgtggag
tgtgtgtctagttcagaggtagacagcctgcgccactctcgctcccgactgaacatctat
aaggctctggcaagcccctcactcattgccttatcaagtgaggaccccatcctaactgcc
ttccgtctgggctgggagctcaaggagctcagcaaggtggagaatgagttcaaggccgag
tatgaggagctctctcagcagtgcaagctctttgccaaagacctgctggaccaagctcgg
agctccagggaactggagatcatcctcaaccatcgagatgaccacagtgaagagcttgac
cctcagaagtaccatgacctggccaagttgaaggtggcaatcaaataccaccagaaagag
tttgttgctcagcccaactgccaacagttgcttgccaccctgtggtatgatggcttccct
ggatggcggcggaaacactgggtagtcaagcttctaacctgcatgaccattgggttcctg
tttcccatgctgtctatagcctacctgatctcacccaggagcaaccttgggctgttcatc
aagaaaccctttatcaagtttatctgccacacagcatcctatttgaccttcctctttatg
cttctcctggcttctcagcacattgtcaggacagaccttcatgtacaggggcctccccca
actgtcgtggaatggatgatattgccttgggttctaggtttcatttggggtgagattaag
gaaatgtgggatggtggatttactgaatacatccatgactggtggaacctgatggatttt
gcaatgaactccctctacctggcaactatttccctgaagattgtggcctatgtcaagtat
aatggttctcgtccaagggaggaatgggaaatgtggcacccgactctgattgcggaagca
ctcttcgcaatatccaacattttaagttcgttgcgtctcatatccctgttcacagccaac
tcccacttaggacctctgcagatctctttgggacgcatgctgcttgatatcctcaaattc
ctctttatctactgcctggtactactagcttttgccaatggactgaaccagctttacttc
tattatgaaaccagagctatcgatgagcctaacaactgcaaggggatccgatgtgagaaa
cagaacaatgccttctccacgctctttgagactcttcagtcactcttctggtctgtattt
ggccttttaaatctatatgtcaccaatgtgaaagccagacacgaattcaccgagtttgta
ggagctaccatgtttggaacatacaatgtcatctccctggtagtgctgctgaacatgctg
attgctatgatgaacaactcctatcagcttattgccgatcatgctgatatcgagtggaag
tttgcaaggacgaagctctggatgagttactttgatgaaggtggcaccttgccacctcct
ttcaacatcatccccagccccaagtcatttctataccttggtaactggttcaacaacacc
ttctgccccaaaagagaccctgacggtagacggagaaggcgcaacttgagaagtttcaca
gaacgcaatgctgacagcctgatacaaaatcaacattatcaggaagttatcaggaattta
gtcaaaagatatgtggctgctatgataagaaattccaaaacacatgagggacttacagaa
gaaaattttaaggaattaaagcaagacatctccagctttcggtatgaagtgcttgacctc
ttgggaaatagaaaacatccaaggagcttttccactagcagcactgaactgtctcagaga
gacgataataatgatggcagtggtggggctcgggccaaatccaagagtgtctcttttaat
ttaggctgcaagaaaaagacttgccatgggccacctctcatcagaaccatgccaaggtcc
agtggtgcccaaggaaagtcaaaagctgagtcatcaagcaaacgctccttcatgggtcct
tctctcaagaaactgggtctcctattctccaaatttaatggtcatatgtctgaacccagt
tcagagccaatgtacacaatttctgatggaattgttcagcagcactgtatgtggcaggac
atcagatattctcagatggagaaagggaaagcagaggcctgttctcaaagtgaaattaac
ctcagtgaggtagaattaggtgaagtccagggcgctgctcagagcagtgaatgccctcta
gcctgttccagctctcttcactgtgcatccagcatctgctcctcaaattctaaactttta
gactcctcagaggatgtatttgaaacttggggagaggcttgtgacttgctcatgcacaaa
tggggtgatggacaggaagaacaagttacaactcgcctctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (13)   
   RefSeq(nuc) (5)   
   GenBank (4)   
   EMBL (4)   
3D Structure (9)   
   PDB (9)   
Protein domain (7)   
   Pfam (7)   
All databases (61)   

Download RDF
DBGET integrated database retrieval system