KEGG   Homo sapiens (human): 7226
Entry
7226              CDS       T01001                                 
Symbol
TRPM2, EREG1, KNP3, LTRPC2, LTrpC-2, NUDT9H, NUDT9L1, TRPC7
Name
(RefSeq) transient receptor potential cation channel subfamily M member 2
  KO
K04977  transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa04921  Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    7226 (TRPM2)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    7226 (TRPM2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7226 (TRPM2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.13  ADP-ribose diphosphatase
     7226 (TRPM2)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7226 (TRPM2)
SSDB
Motif
Pfam: LSDAT_euk LSDAT_prok Ion_trans
Other DBs
NCBI-GeneID: 7226
NCBI-ProteinID: NP_003298
OMIM: 603749
HGNC: 12339
Ensembl: ENSG00000142185
UniProt: O94759
Structure
Position
21:44353621..44442644
AA seq 1503 aa
MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSWRLQCPFGNNDKQESLS
SWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEATKPHTFQGTQWDPKKHVQ
EMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQHWGLDVPNLLISVTGGAKNF
NMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQVGEAVRDFSLSSSYKEGELITIG
VATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTCLDSNHSHFILVDDGTHGQYGVEIP
LRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGPGTLHTIDNATTNGTPCVVVEGSGRVA
DVIAQVANLPVSDITISLIQQKLSVFFQEMFETFTESRIVEWTKKIQDIVRRRQLLTVFR
EGKDGQQDVDVAILQALLKASRSQDHFGHENWDHQLKLAVAWNRVDIARSEIFMDEWQWK
PSDLHPTMTAALISNKPEFVKLFLENGVQLKEFVTWDTLLYLYENLDPSCLFHSKLQKVL
VEDPERPACAPAAPRLQMHHVAQVLRELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQ
GVSLRSLYKRSSGHVTFTMDPIRDLLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILK
ELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQL
ALEAKDMKFVSHGGIQAFLTKVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQD
VGTPAARARAFFTAPVVVFHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLV
CEEMRQLFYDPDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILS
LDFILFCLRLMHIFTISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNE
RRVDWLFRGAVYHSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAF
PEWLTVLLLCLYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAA
PPPFILLSHLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQ
KQRPEQKIEDISNKVDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTAQALHWIVRTLRA
SGFSSEADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNE
KVPWETEFLIYDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQ
AGLPLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLP
LSEHWALPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWI
ETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFG
AHY
NT seq 4512 nt   +upstreamnt  +downstreamnt
atggagccctcagccctgaggaaagctggctcggagcaggaggagggctttgaggggctg
cccagaagggtcactgacctggggatggtctccaatctccggcgcagcaacagcagcctc
ttcaagagctggaggctacagtgccccttcggcaacaatgacaagcaagaaagcctcagt
tcgtggattcctgaaaacatcaagaagaaagaatgcgtgtattttgtggaaagttccaaa
ctgtctgatgctgggaaggtggtgtgtcagtgtggctacacgcatgagcagcacttggag
gaggctaccaagccccacaccttccagggcacacagtgggacccaaagaaacatgtccag
gagatgccaaccgatgcctttggcgacatcgtcttcacgggcctgagccagaaggtgaaa
aagtacgtccgagtctcccaggacacgccctccagcgtgatctaccacctcatgacccag
cactgggggctggacgtccccaatctcttgatctcggtgaccgggggggccaagaacttc
aacatgaagccgcggctgaagagcattttccgcagaggcctggtcaaggtggctcagacc
acaggggcctggatcatcacaggggggtcccacaccggcgtcatgaagcaggtaggcgag
gcggtgcgggacttcagcctgagcagcagctacaaggaaggcgagctcatcaccatcgga
gtcgccacctggggcactgtccaccgccgcgagggcctgatccatcccacgggcagcttc
cccgccgagtacatactggatgaggatggccaagggaacctgacctgcctagacagcaac
cactctcacttcatcctcgtggacgacgggacccacggccagtacggggtggagattcct
ctgaggaccaggctggagaagttcatatcggagcagaccaaggaaagaggaggtgtggcc
atcaagatccccatcgtgtgcgtggtgctggagggcggcccgggcacgttgcacaccatc
gacaacgccaccaccaacggcaccccctgtgtggttgtggagggctcgggccgcgtggcc
gacgtcattgcccaggtggccaacctgcctgtctcggacatcactatctccctgatccag
cagaaactgagcgtgttcttccaggagatgtttgagaccttcacggaaagcaggattgtc
gagtggaccaaaaagatccaagatatcgtccggaggcggcagctgctgactgtcttccgg
gaaggcaaggatggtcagcaggacgtggatgtggccatcttgcaggccttgctgaaagcc
tcacggagccaagaccactttggccacgagaactgggaccaccagctgaaactggcagtg
gcatggaatcgcgtggacattgcccgcagtgagatcttcatggatgagtggcagtggaag
ccttcagatctgcaccccacgatgacagctgcactcatctccaacaagcctgagtttgtg
aagctcttcctggagaacggggtgcagctgaaggagtttgtcacctgggacaccttgctc
tacctgtacgagaacctggacccctcctgcctgttccacagcaagctgcagaaggtgctg
gtggaggatcccgagcgcccggcttgcgcgcccgcggcgccccgcctgcagatgcaccac
gtggcccaggtgctgcgggagctgctgggggacttcacgcagccgctttatccccggccc
cggcacaacgaccggctgcggctcctgctgcccgttccccacgtcaagctcaacgtgcag
ggagtgagcctccggtccctctacaagcgttcctcaggccatgtgaccttcaccatggac
cccatccgtgaccttctcatttgggccattgtccagaaccgtcgggagctggcaggaatc
atctgggctcagagccaggactgcatcgcagcggccttggcctgcagcaagatcctgaag
gaactgtccaaggaggaggaggacacggacagctcggaggagatgctggcgctggcggag
gagtatgagcacagagccatcggggtcttcaccgagtgctaccggaaggacgaagagaga
gcccagaaactgctcacccgcgtgtccgaggcctgggggaagaccacctgcctgcagctc
gccctggaggccaaggacatgaagtttgtgtctcacgggggcatccaggccttcctgacc
aaggtgtggtggggccagctctccgtggacaatgggctgtggcgtgtgaccctgtgcatg
ctggccttcccgctgctcctcaccggcctcatctccttcagggagaagaggctgcaggat
gtgggcacccccgcggcccgcgcccgtgccttcttcaccgcacccgtggtggtcttccac
ctgaacatcctctcctacttcgccttcctctgcctgttcgcctacgtgctcatggtggac
ttccagcctgtgccctcctggtgcgagtgtgccatctacctctggctcttctccttggtg
tgcgaggagatgcggcagctcttctatgaccctgacgagtgcgggctgatgaagaaggca
gccttgtacttcagtgacttctggaataagctggacgtcggcgcaatcttgctcttcgtg
gcagggctgacctgcaggctcatcccggcgacgctgtaccccgggcgcgtcatcctctct
ctggacttcatcctgttctgcctccggctcatgcacatttttaccatcagtaagacgctg
gggcccaagatcatcattgtgaagcggatgatgaaggacgtcttcttcttcctcttcctg
ctggctgtgtgggtggtgtccttcggggtggccaagcaggccatcctcatccacaacgag
cgccgggtggactggctgttccgaggggccgtctaccactcctacctcaccatcttcggg
cagatcccgggctacatcgacggtgtgaacttcaacccggagcactgcagccccaatggc
accgacccctacaagcctaagtgccccgagagcgacgcgacgcagcagaggccggccttc
cctgagtggctgacggtcctcctactctgcctctacctgctcttcaccaacatcctgctg
ctcaacctcctcatcgccatgttcaactacaccttccagcaggtgcaggagcacacggac
cagatttggaagttccagcgccatgacctgatcgaggagtaccacggccgccccgccgcg
ccgccccccttcatcctcctcagccacctgcagctcttcatcaagagggtggtcctgaag
actccggccaagaggcacaagcagctcaagaacaagctggagaagaacgaggaggcggcc
ctgctatcctgggagatctacctgaaggagaactacctccagaaccgacagttccagcaa
aagcagcggcccgagcagaagatcgaggacatcagcaataaggttgacgccatggtggac
ctgctggacctggacccactgaagaggtcgggctccatggagcagaggttggcctccctg
gaggagcaggtggcccagacagcccaagccctgcactggatcgtgaggacgctgcgggcc
agcggcttcagctcggaggcggacgtccccactctggcctcccagaaggccgcggaggag
ccggatgctgagccgggaggcaggaagaagacggaggagccgggcgacagctaccacgtg
aatgcccggcacctcctctaccccaactgccctgtcacgcgcttccccgtgcccaacgag
aaggtgccctgggagacggagttcctgatctatgacccacccttttacacggcagagagg
aaggacgcggccgccatggaccccatgggagacaccctggagccactgtccacgatccag
tacaacgtggtggatggcctgagggaccgccggagcttccacgggccgtacacagtgcag
gccgggttgcccctgaaccccatgggccgcacaggactgcgtgggcgcgggagcctcagc
tgcttcggacccaaccacacgctgtaccccatggtcacgcggtggaggcggaacgaggat
ggagccatctgcaggaagagcataaagaagatgctggaagtgctggtggtgaagctccct
ctctccgagcactgggccctgcctgggggctcccgggagccaggggagatgctacctcgg
aagctgaagcggatcctccggcaggagcactggccgtcttttgaaaacttgctgaagtgc
ggcatggaggtgtacaaaggctacatggatgacccgaggaacacggacaatgcctggatc
gagacggtggccgtcagcgtccacttccaggaccagaatgacgtggagctgaacaggctg
aactctaacctgcacgcctgcgactcgggggcctccatccgatggcaggtggtggacagg
cgcatcccactctatgcgaaccacaagaccctcctccagaaggcagccgctgagttcggg
gctcactactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (46)   
   RefSeq(nuc) (16)   
   GenBank (15)   
   EMBL (15)   
3D Structure (9)   
   PDB (9)   
Protein domain (3)   
   Pfam (3)   
All databases (109)   

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