KEGG   Homo sapiens (human): 7358
Entry
7358              CDS       T01001                                 
Symbol
UGDH, DEE84, EIEE84, GDH, UDP-GlcDH, UDPGDH, UGD
Name
(RefSeq) UDP-glucose 6-dehydrogenase
  KO
K00012  UDPglucose 6-dehydrogenase [EC:1.1.1.22]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa00053  Ascorbate and aldarate metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
hsa01250  Biosynthesis of nucleotide sugars
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    7358 (UGDH)
   00053 Ascorbate and aldarate metabolism
    7358 (UGDH)
   00520 Amino sugar and nucleotide sugar metabolism
    7358 (UGDH)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.22  UDP-glucose 6-dehydrogenase
     7358 (UGDH)
SSDB
Motif
Pfam: UDPG_MGDP_dh_N UDPG_MGDP_dh UDPG_MGDP_dh_C DUF4853 Sacchrp_dh_NADP
Other DBs
NCBI-GeneID: 7358
NCBI-ProteinID: NP_003350
OMIM: 603370
HGNC: 12525
Ensembl: ENSG00000109814
UniProt: O60701
Structure
Position
4:complement(39498755..39527439)
AA seq 494 aa
MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV
VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS
NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI
GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL
CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW
QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE
GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF
KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP
KFSLQDPPNKKPKV
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgtttgaaattaagaagatctgttgcatcggtgcaggctatgttggaggacccacatgt
agtgtcattgctcatatgtgtcctgaaatcagggtaacggttgttgatgtcaatgaatca
agaatcaatgcgtggaattctcctacacttcctatttatgagccaggactaaaagaagtg
gtagaatcctgtcgaggaaaaaatctttttttttctaccaatattgatgatgccatcaaa
gaagctgatcttgtatttatttctgtgaatactccaacaaaaacctatggaatggggaaa
ggccgggcagcagatctgaagtatattgaagcttgtgctagacgcattgtgcaaaactca
aatgggtacaaaattgtgactgagaaaagcacagttccagtgcgggcagcagaaagtatc
cgtcgcatatttgatgcaaacacaaaacccaacttgaatttacaggtgctgtccaaccct
gagtttctggcagagggaacagccatcaaggacctaaagaacccagacagagtactgatt
ggaggggatgaaactccagagggccagagagctgtgcaggccctgtgtgctgtatatgag
cactgggttcccagagaaaagatcctcaccactaatacttggtcttcagagctttccaaa
ctggcagcaaatgcttttcttgcccagagaataagcagcattaactccataagtgctctg
tgtgaagcaacaggagctgatgtagaagaggtagcaacagcgattggaatggaccagaga
attggaaacaagtttctaaaagccagtgttgggtttggtgggagctgtttccaaaaggat
gttctgaatttggtttatctctgtgaggctctgaatttgccagaagtagctcgttattgg
cagcaggtcatagacatgaatgactaccagaggaggaggtttgcttcccggatcatagat
agtctgtttaatacagtaactgataagaagatagctattttgggatttgcattcaaaaag
gacactggtgatacaagagaatcttctagtatatatattagcaaatatttgatggatgaa
ggtgcacatctacatatatatgatccaaaagtacctagggaacaaatagttgtggatctt
tctcatccaggtgtttcagaggatgaccaagtgtcccggctcgtgaccatttccaaggat
ccatatgaagcatgtgatggtgcccatgctgttgttatttgcactgagtgggacatgttt
aaggaattggattatgaacgcattcataaaaaaatgctaaagccagcctttatcttcgat
ggacggcgtgtcctggatgggctccacaatgaactacaaaccattggcttccagattgaa
acaattggcaaaaaggtgtcttcaaagagaattccatatgctccttctggtgaaattccg
aagtttagtcttcaagatccacctaacaagaaacctaaagtgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
3D Structure (18)   
   PDB (18)   
Protein domain (5)   
   Pfam (5)   
All databases (99)   

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