KEGG   Homo sapiens (human): 7375
Entry
7375              CDS       T01001                                 
Symbol
USP4, UNP, Unph
Name
(RefSeq) ubiquitin specific peptidase 4
  KO
K11835  ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    7375 (USP4)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    7375 (USP4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     7375 (USP4)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   7375 (USP4)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    7375 (USP4)
SSDB
Motif
Pfam: UCH Ubiquitin_3 DUSP UCH_1 USP7_C2 USP7_ICP0_bdg
Other DBs
NCBI-GeneID: 7375
NCBI-ProteinID: NP_003354
OMIM: 603486
HGNC: 12627
Ensembl: ENSG00000114316
UniProt: Q13107 Q08AK7
Structure
Position
3:complement(49277144..49340053)
AA seq 963 aa
MAEGGGCRERPDAETQKSELGPLMRTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVG
EHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRK
VVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERE
TRLWNKYMSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRN
FTTSPKSSASPYSSVSASLIANGDSTSTCGMHSSGVSRGGSGFSASYNCQEPPSSHIQPG
LCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIK
QMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLEL
KDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLP
LPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEALSRLSGIAAENMVVADVYN
HRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASAL
YGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGED
EEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKGQPCPKRLFTFSLVNSYGTADI
NSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRD
CIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDT
VVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDS
NVSLASEDQIVTKAAYVLFYQRRDDEFYKTPSLSSSGSSDGGTRPSSSQQGFGDDEACSM
DTN
NT seq 2892 nt   +upstreamnt  +downstreamnt
atggcggaaggtggaggctgccgtgagcgaccggatgcggagactcagaagtccgagctt
ggacccttaatgaggaccacactccaacgcggggcgcagtggtatcttattgacagccgg
tggttcaagcagtggaagaagtatgtgggctttgacagctgggacatgtacaatgtgggt
gaacataacctatttcctggcccaatagacaactctgggctattttcagatcctgagagt
cagaccttgaaagaacacttaattgatgaattggactatgtattggtccctaccgaggcg
tggaataaactactaaactggtacggctgtgtagaaggccagcaacccatcgtcagaaaa
gttgtggagcatggcctgtttgtcaagcactgcaaagtcgaggtgtatttgctggaactg
aagctctgtgagaacagtgaccccaccaatgtgctgagttgccatttcagcaaggcagac
accattgcaaccatcgagaaagagatgcggaagctattcaacatccctgcggagcgtgaa
acacggctctggaacaaatacatgagcaacacctacgagcagttgagcaagctagacaac
actgtccaggatgctgggctataccagggtcaggtgctagtaattgagcctcaaaatgaa
gatggcacatggcccaggcagaccttgcagtcaaaatcaagcactgcgcctagcagaaat
tttactacctctccaaaatcatcagcaagtccctattcctcagtgtctgcctctctcatt
gcaaatggtgatagcactagcacctgtgggatgcacagttccggtgtcagcaggggtgga
tctggcttttctgcttcgtataattgtcaggagccaccatcctctcatatacaacctggg
ctctgtggacttggaaacctgggaaacacctgcttcatgaactccgctttgcagtgtttg
agcaacactgcaccactgactgactactttctcaaagatgagtatgaagccgaaatcaac
agagacaaccctctggggatgaaaggggaaattgcagaagcctatgctgaactcattaag
cagatgtggtctggaagggacgcccatgtggcacctcgcatgttcaaaactcaagtagga
cgttttgctcctcaattttctggctaccagcaacaagattctcaggagctgctggccttt
cttctagatggattgcatgaagatctgaaccgggtaaagaaaaagccctacttggagctg
aaggatgccaatgggcggccagatgcggtggtggcaaaggaagcctgggagaatcacagg
ttgaggaatgattctgtgattgtggatactttccatggcctcttcaaatctactttggtt
tgcccagaatgtgctaaggtttctgtgacctttgacccattttgctatctaacgctgcca
ctgcccttgaagaaagatcgagttatggaggttttcctggttcctgctgaccctcactgc
agacctactcagtaccgtgtgactgtgccgctgatgggggctgtgtccgacctgtgcgag
gctctctccaggctgtctggcattgctgcagaaaatatggtggtcgcagatgtgtataat
caccgattccacaaaattttccaaatggatgaaggtttaaaccacatcatgcctcgggat
gacattttcgtgtacgaggtctgcagcacttccgtggatggctcggaatgtgtcacgctt
ccagtctacttcagggagaggaagtccaggccatcaagcacttcctccgcatcagcgcta
tatgggcagccactattgctttctgtccccaagcacaagttaacccttgagtctttgtac
caggctgtttgtgatcgtatcagccgctatgtgaaacagcctttacctgatgagtttggc
agctcacccttggagccaggggcctgcaatggctccaggaacagctgtgaaggagaagat
gaggaagaaatggagcatcaggaagaaggcaaagagcagctttcagaaacagaaggcagt
ggggaagatgagccaggaaatgaccccagtgagaccacccaaaagaagatcaaaggccag
ccctgcccaaaaaggctttttaccttcagtcttgtgaactcctatggaacagctgacata
aattcacttgcagctgatggaaaactacttaaactcaactctcgatctacactggccatg
gattgggacagtgaaactcggagactttactatgatgagcaagaatctgaggcctacgag
aagcatgtgagcatgttgcagcctcagaagaagaagaagaccacagtggccctgagagac
tgcatcgagctcttcaccaccatggagacccttggggagcatgacccctggtactgtccc
aactgtaagaagcatcaacaggccacaaaaaagtttgacctatggtccttgcccaagatc
ctggtggtccacctcaaacgtttctcctacaacagatactggagggataagctcgacaca
gtcgtagaattcccaatcagagggctgaacatgtccgagtttgtctgtaacctgtcagca
aggccttatgtgtacgacctcattgccgtgtccaatcattatggagccatgggggttggc
cactacactgcatatgcgaagaacaaactgaatggtaaatggtattactttgatgatagc
aacgtgtccctggcctctgaggatcagatagtgactaaagcagcttatgtgctattttac
caacgtcgagatgatgaattttataagacaccttcacttagcagttctggttcctctgat
ggagggacacgaccaagcagctctcagcagggctttggggatgatgaggcttgcagcatg
gacaccaactaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (30)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (33)   
   RefSeq(nuc) (3)   
   GenBank (15)   
   EMBL (15)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (84)   

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