KEGG   Homo sapiens (human): 7436
Entry
7436              CDS       T01001                                 
Symbol
VLDLR, CAMRQ1, CARMQ1, CHRMQ1, VLDL-R, VLDLRCH
Name
(RefSeq) very low density lipoprotein receptor
  KO
K20053  very low-density lipoprotein receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa05017  Spinocerebellar ataxia
hsa05417  Lipid and atherosclerosis
Network
nt06462  Spinocerebellar ataxia
  Element
N00963  RELN-VLDLR-PI3K signaling pathway
N00964  DAB1-overexpression to RELN-VLDLR-PI3K signaling pathway
Disease
H01204  Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    7436 (VLDLR)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    7436 (VLDLR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    7436 (VLDLR)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    7436 (VLDLR)
SSDB
Motif
Pfam: Ldl_recept_a Ldl_recept_b FXa_inhibition cEGF EGF_CA SGL EGF Mucin hEGF DUF4010
Other DBs
NCBI-GeneID: 7436
NCBI-ProteinID: NP_003374
OMIM: 192977
HGNC: 12698
Ensembl: ENSG00000147852
UniProt: P98155
Structure
Position
9:2621787..2660056
AA seq 873 aa
MGTSALWALWLLLALCWAPRESGATGTGRKAKCEPSQFQCTNGRCITLLWKCDGDEDCVD
GSDEKNCVKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISC
GAHSTQCIPVSWRCDGENDCDSGEDEENCGNITCSPDEFTCSSGRCISRNFVCNGQDDCS
DGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADCSDQSDESLEQCGRQPVIHTKCP
ASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGI
RDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHINEC
LVNNGGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCE
CSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAA
QKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVA
TLDGTKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTADIQ
WPNGITLDLIKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWI
DGENEAVYGANKFTGSELATLVNNLNDAQDIIVYHELVQPSGKNWCEEDMENGGCEYLCL
PAPQINDHSPKYTCSCPSGYNVEENGRDCQSTATTVTYSETKDTNTTEISATSGLVPGGI
NVTTAVSEVSVPPKGTSAAWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKT
TEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA
NT seq 2622 nt   +upstreamnt  +downstreamnt
atgggcacgtccgcgctctgggcgctctggctgctgctcgcgctgtgctgggcgccccgg
gagagcggcgccaccggaaccgggagaaaagccaaatgtgaaccctcccaattccagtgc
acaaatggtcgctgtattacgctgttgtggaaatgtgatggggatgaagactgtgttgac
ggcagtgatgaaaagaactgtgtaaagaagacgtgtgctgaatctgacttcgtgtgcaac
aatggccagtgtgttcccagccgatggaagtgtgatggagatcctgactgcgaagatggt
tcagatgaaagcccagaacagtgccatatgagaacatgccgcatacatgaaatcagctgt
ggcgcccattctactcagtgtatcccagtgtcctggagatgtgatggtgaaaatgattgt
gacagtggagaagatgaagaaaactgtggcaatataacatgtagtcccgacgagttcacc
tgctccagtggccgctgcatctccaggaactttgtatgcaatggccaggatgactgcagc
gatggcagtgatgagctggactgtgccccgccaacctgtggcgcccatgagttccagtgc
agcacctcctcctgcatccccatcagctgggtatgcgacgatgatgcagactgctccgac
caatctgatgagtccctggagcagtgtggccgtcagccagtcatacacaccaagtgtcca
gccagcgaaatccagtgcggctctggcgagtgcatccataagaagtggcgatgtgatggg
gaccctgactgcaaggatggcagtgatgaggtcaactgtccctctcgaacttgccgacct
gaccaatttgaatgtgaggatggcagctgcatccatggcagcaggcagtgtaatggtatc
cgagactgtgtcgatggttccgatgaagtcaactgcaaaaatgtcaatcagtgcttgggc
cctggaaaattcaagtgcagaagtggagaatgcatagatatcagcaaagtatgtaaccag
gagcaggactgcagggactggagtgatgagcccctgaaagagtgtcatataaacgaatgc
ttggtaaataatggtggatgttctcatatctgcaaagacctagttataggctacgagtgt
gactgtgcagctgggtttgaactgatagataggaaaacctgtggagatattgatgaatgc
caaaatccaggaatctgcagtcaaatttgtatcaacttaaaaggcggttacaagtgtgaa
tgtagtcgtggctatcaaatggatcttgctactggcgtgtgcaaggcagtaggcaaagag
ccaagtctgatcttcactaatcgaagagacatcaggaagattggcttagagaggaaagaa
tatatccaactagttgaacagctaagaaacactgtggctctcgatgctgacattgctgcc
cagaaactattctgggccgatctaagccaaaaggctatcttcagtgcctcaattgatgac
aaggttggtagacatgttaaaatgatcgacaatgtctataatcctgcagccattgctgtt
gattgggtgtacaagaccatctactggactgatgcggcttctaagactatttcagtagct
accctagatggaaccaagaggaagttcctgtttaactctgacttgcgagagcctgcctcc
atagctgtggacccactgtctggctttgtttactggtcagactggggtgaaccagctaaa
atagaaaaagcaggaatgaatggattcgatagacgtccactggtgacagcggatatccag
tggcctaacggaattacacttgaccttataaaaagtcgcctctattggcttgattctaag
ttgcacatgttatccagcgtggacttgaatggccaagatcgtaggatagtactaaagtct
ctggagttcctagctcatcctcttgcactaacaatatttgaggatcgtgtctactggata
gatggggaaaatgaagcagtctatggtgccaataaattcactggatcagagctagccact
ctagtcaacaacctgaatgatgcccaagacatcattgtctatcatgaacttgtacagcca
tcaggtaaaaattggtgtgaagaagacatggagaatggaggatgtgaatacctatgcctg
ccagcaccacagattaatgatcactctccaaaatatacctgttcctgtcccagtgggtac
aatgtagaggaaaatggccgagactgtcaaagtactgcaactactgtgacttacagtgag
acaaaagatacgaacacaacagaaatttcagcaactagtggactagttcctggagggatc
aatgtgaccacagcagtatcagaggtcagtgttcccccaaaagggacttctgccgcatgg
gccattcttcctctcttgctcttagtgatggcagcagtaggtggctacttgatgtggcgg
aattggcaacacaagaacatgaaaagcatgaactttgacaatcctgtgtacttgaaaacc
actgaagaggacctctccatagacattggtagacacagtgcttctgttggacacacgtac
ccagcaatatcagttgtaagcacagatgatgatctagcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (34)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (14)   
3D Structure (4)   
   PDB (4)   
Protein domain (10)   
   Pfam (10)   
All databases (92)   

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