KEGG   Homo sapiens (human): 7442
Entry
7442              CDS       T01001                                 
Symbol
TRPV1, VR1
Name
(RefSeq) transient receptor potential cation channel subfamily V member 1
  KO
K05222  transient receptor potential cation channel subfamily V member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04750  Inflammatory mediator regulation of TRP channels
Drug target
Capsaicin: D00250<US>
Mavatrep: D10370
Motugivatrep: D12841
Nonivamide: D08282
Olvanil: D05249
Zucapsaicin: D06388
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    7442 (TRPV1)
 09150 Organismal Systems
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    7442 (TRPV1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    7442 (TRPV1)
Ion channels [BR:hsa04040]
 Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   7442 (TRPV1)
SSDB
Motif
Pfam: Ank_2 Ank Ion_trans Ank_3 Ank_5 Ank_4
Other DBs
NCBI-GeneID: 7442
NCBI-ProteinID: NP_061197
OMIM: 602076
HGNC: 12716
Ensembl: ENSG00000196689
UniProt: Q8NER1
Structure
Position
17:complement(3565446..3609411)
AA seq 839 aa
MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
NT seq 2520 nt   +upstreamnt  +downstreamnt
atgaagaaatggagcagcacagacttgggggcagctgcggacccactccaaaaggacacc
tgcccagaccccctggatggagaccctaactccaggccacctccagccaagccccagctc
tccacggccaagagccgcacccggctctttgggaagggtgactcggaggaggctttcccg
gtggattgccctcacgaggaaggtgagctggactcctgcccgaccatcacagtcagccct
gttatcaccatccagaggccaggagacggccccaccggtgccaggctgctgtcccaggac
tctgtcgccgccagcaccgagaagaccctcaggctctatgatcgcaggagtatctttgaa
gccgttgctcagaataactgccaggatctggagagcctgctgctcttcctgcagaagagc
aagaagcacctcacagacaacgagttcaaagaccctgagacagggaagacctgtctgctg
aaagccatgctcaacctgcacgacggacagaacaccaccatccccctgctcctggagatc
gcgcggcaaacggacagcctgaaggagcttgtcaacgccagctacacggacagctactac
aagggccagacagcactgcacatcgccatcgagagacgcaacatggccctggtgaccctc
ctggtggagaacggagcagacgtccaggctgcggcccatggggacttctttaagaaaacc
aaagggcggcctggattctacttcggtgaactgcccctgtccctggccgcgtgcaccaac
cagctgggcatcgtgaagttcctgctgcagaactcctggcagacggccgacatcagcgcc
agggactcggtgggcaacacggtgctgcacgccctggtggaggtggccgacaacacggcc
gacaacacgaagtttgtgacgagcatgtacaatgagattctgatgctgggggccaaactg
cacccgacgctgaagctggaggagctcaccaacaagaagggaatgacgccgctggctctg
gcagctgggaccgggaagatcggggtcttggcctatattctccagcgggagatccaggag
cccgagtgcaggcacctgtccaggaagttcaccgagtgggcctacgggcccgtgcactcc
tcgctgtacgacctgtcctgcatcgacacctgcgagaagaactcggtgctggaggtgatc
gcctacagcagcagcgagacccctaatcgccacgacatgctcttggtggagccgctgaac
cgactcctgcaggacaagtgggacagattcgtcaagcgcatcttctacttcaacttcctg
gtctactgcctgtacatgatcatcttcaccatggctgcctactacaggcccgtggatggc
ttgcctccctttaagatggaaaaaactggagactatttccgagttactggagagatcctg
tctgtgttaggaggagtctacttctttttccgagggattcagtatttcctgcagaggcgg
ccgtcgatgaagaccctgtttgtggacagctacagtgagatgcttttctttctgcagtca
ctgttcatgctggccaccgtggtgctgtacttcagccacctcaaggagtatgtggcttcc
atggtattctccctggccttgggctggaccaacatgctctactacacccgcggtttccag
cagatgggcatctatgccgtcatgatagagaagatgatcctgagagacctgtgccgtttc
atgtttgtctacatcgtcttcttgttcgggttttccacagcggtggtgacgctgattgaa
gacgggaagaatgactccctgccgtctgagtccacgtcgcacaggtggcgggggcctgcc
tgcaggccccccgatagctcctacaacagcctgtactccacctgcctggagctgttcaag
ttcaccatcggcatgggcgacctggagttcactgagaactatgacttcaaggctgtcttc
atcatcctgctgctggcctatgtaattctcacctacatcctcctgctcaacatgctcatc
gccctcatgggtgagactgtcaacaagatcgcacaggagagcaagaacatctggaagctg
cagagagccatcaccatcctggacacggagaagagcttccttaagtgcatgaggaaggcc
ttccgctcaggcaagctgctgcaggtggggtacacacctgatggcaaggacgactaccgg
tggtgcttcagggtggacgaggtgaactggaccacctggaacaccaacgtgggcatcatc
aacgaagacccgggcaactgtgagggcgtcaagcgcaccctgagcttctccctgcggtca
agcagagtttcaggcagacactggaagaactttgccctggtcccccttttaagagaggca
agtgctcgagataggcagtctgctcagcccgaggaagtttatctgcgacagttttcaggg
tctctgaagccagaggacgctgaggtcttcaagagtcctgccgcttccggggagaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (34)   
   RefSeq(nuc) (4)   
   GenBank (15)   
   EMBL (15)   
3D Structure (4)   
   PDB (4)   
Protein domain (6)   
   Pfam (6)   
All databases (83)   

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