KEGG   Homo sapiens (human): 7490
Entry
7490              CDS       T01001                                 
Symbol
WT1, AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33
Name
(RefSeq) WT1 transcription factor
  KO
K09234  Wilms tumor protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00137  EWSR1-WT1 fusion to transcriptional activation
Disease
H00607  46,XY gonadal dysgenesis
H01657  Nephrotic syndrome
H01985  Desmoplastic small round cell tumor
H02301  Nephroblastoma
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    7490 (WT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    7490 (WT1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys2His2 SP/KLF family and related proteins
    7490 (WT1)
SSDB
Motif
Pfam: WT1 zf-H2C2_2 zf-C2H2 zf-C2H2_4 FOXP-CC zf-C2H2_aberr zf-met Zap1_zf1
Other DBs
NCBI-GeneID: 7490
NCBI-ProteinID: NP_000369
OMIM: 607102
HGNC: 12796
Ensembl: ENSG00000184937
UniProt: P19544 Q6PI38
Structure
Position
11:complement(32387775..32435539)
AA seq 502 aa
MDFLLLQDPASTCVPEPASQHTLRSGPGCLQQPEQQGVRDPGGIWAKLGAAEASAERLQG
RRSRGASGSEPQQMGSDVRDLNALLPAVPSLGGGGGCALPVSGAAQWAPVLDFAPPGASA
YGSLGGPAPPPAPPPPPPPPPHSFIKQEPSWGGAEPHEEQCLSAFTVHFSGQFTGTAGAC
RYGPFGPPPPSQASSGQARMFPNAPYLPSCLESQPAIRNQGYSTVTFDGTPSYGHTPSHH
AAQFPNHSFKHEDPMGQQGSLGEQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLY
QMTSQLECMTWNQMNLGATLKGHSTGYESDNHTTPILCGAQYRIHTHGVFRGIQDVRRVP
GVAPTLVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRF
SRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQKKFAR
SDELVRHHNMHQRNMTKLQLAL
NT seq 1509 nt   +upstreamnt  +downstreamnt
ctggacttcctcttgctgcaggacccggcttccacgtgtgtcccggagccggcgtctcag
cacacgctccgctccgggcctgggtgcctacagcagccagagcagcagggagtccgggac
ccgggcggcatctgggccaagttaggcgccgccgaggccagcgctgaacgtctccagggc
cggaggagccgcggggcgtccgggtctgagccgcagcaaatgggctccgacgtgcgggac
ctgaacgcgctgctgcccgccgtcccctccctgggtggcggcggcggctgtgccctgcct
gtgagcggcgcggcgcagtgggcgccggtgctggactttgcgcccccgggcgcttcggct
tacgggtcgttgggcggccccgcgccgccaccggctccgccgccacccccgccgccgccg
cctcactccttcatcaaacaggagccgagctggggcggcgcggagccgcacgaggagcag
tgcctgagcgccttcactgtccacttttccggccagttcactggcacagccggagcctgt
cgctacgggcccttcggtcctcctccgcccagccaggcgtcatccggccaggccaggatg
tttcctaacgcgccctacctgcccagctgcctcgagagccagcccgctattcgcaatcag
ggttacagcacggtcaccttcgacgggacgcccagctacggtcacacgccctcgcaccat
gcggcgcagttccccaaccactcattcaagcatgaggatcccatgggccagcagggctcg
ctgggtgagcagcagtactcggtgccgcccccggtctatggctgccacacccccaccgac
agctgcaccggcagccaggctttgctgctgaggacgccctacagcagtgacaatttatac
caaatgacatcccagcttgaatgcatgacctggaatcagatgaacttaggagccacctta
aagggccacagcacagggtacgagagcgataaccacacaacgcccatcctctgcggagcc
caatacagaatacacacgcacggtgtcttcagaggcattcaggatgtgcgacgtgtgcct
ggagtagccccgactcttgtacggtcggcatctgagaccagtgagaaacgccccttcatg
tgtgcttacccaggctgcaataagagatattttaagctgtcccacttacagatgcacagc
aggaagcacactggtgagaaaccataccagtgtgacttcaaggactgtgaacgaaggttt
tctcgttcagaccagctcaaaagacaccaaaggagacatacaggtgtgaaaccattccag
tgtaaaacttgtcagcgaaagttctcccggtccgaccacctgaagacccacaccaggact
catacaggtgaaaagcccttcagctgtcggtggccaagttgtcagaaaaagtttgcccgg
tcagatgaattagtccgccatcacaacatgcatcagagaaacatgaccaaactccagctg
gcgctttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (13)   
   KEGG DISEASE (4)   
   OMIM (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (48)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PRONIT (26)   
Protein sequence (21)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (18)   
DNA sequence (42)   
   RefSeq(nuc) (20)   
   GenBank (11)   
   EMBL (11)   
3D Structure (26)   
   PDB (26)   
Protein domain (8)   
   Pfam (8)   
All databases (164)   

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