KEGG   Homo sapiens (human): 7512
Entry
7512              CDS       T01001                                 
Symbol
XPNPEP2, AEACEI, APP2
Name
(RefSeq) X-prolyl aminopeptidase 2
  KO
K14208  Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    7512 (XPNPEP2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    7512 (XPNPEP2)
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    7512 (XPNPEP2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.11  Aminopeptidases
    3.4.11.9  Xaa-Pro aminopeptidase
     7512 (XPNPEP2)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M24
   7512 (XPNPEP2)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  7512 (XPNPEP2)
SSDB
Motif
Pfam: Creatinase_N_2 Peptidase_M24 Peptidase_M24_C Creatinase_N
Other DBs
NCBI-GeneID: 7512
NCBI-ProteinID: NP_003390
OMIM: 300145
HGNC: 12823
Ensembl: ENSG00000122121
UniProt: O43895
Position
X:129738979..129769536
AA seq 674 aa
MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQ
MQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQ
AERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQL
VSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLS
ALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCV
QIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSK
EQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETIS
ASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYT
RVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQ
SNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNL
IDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWAS
VLVVSTLAILGWSV
NT seq 2025 nt   +upstreamnt  +downstreamnt
atggcccgggctcactggggctgctgcccctggctggtcctcctctgtgcttgtgcctgg
ggccacacaaagccagtggaccttggagggcaggatgtgagaaactgttccaccaacccc
ccttaccttccagttactgtggtcaataccacaatgtcactcacagccctccgccagcag
atgcagacccagaatctctcagcctacatcatcccaggcacagatgctcacatgaacgag
tacatcggccaacatgacgagaggcgtgcgtggattacaggctttacagggtctgcagga
actgcagtggtgactatgaagaaagcagctgtctggaccgacagtcgctactggactcag
gctgagcggcagatggactgcaactgggagctccataaggaagttggcaccactcctatt
gtcacctggctcctcaccgagattcctgctggagggcgtgtgggttttgaccccttcctc
ttgtccattgacacctgggagagttatgatctggccctccaaggctctaacagacagctg
gtgtccatcacaaccaatcttgtggacctggtatggggatcagagaggccaccggttcca
aatcaacccatttatgccctgcaggaggcattcacagggagcacttggcaggagaaagta
tctggcgtccgaagccagatgcagaagcatcaaaaggtcccgactgccgtccttctgtcg
gcgcttgaggagacggcctggctcttcaaccttcgagccagtgacatcccctataacccc
ttcttctattcctacacgctgctcacagactcttctattaggttgtttgcaaacaagagt
cgctttagctccgaaaccttgagctatctgaactccagttgcacaggccccatgtgtgtg
caaatcgaggattacagccaagttcgtgacagcatccaggcctactcattgggagatgtg
aggatctggattgggaccagctataccatgtatgggatctatgaaatgatacccaaggag
aaactcgtgacagacacctactccccagtgatgatgaccaaggcagtgaagaacagcaag
gagcaggccctcctcaaggccagccacgtgcgggacgctgtggctgtgatccggtacttg
gtctggctggagaagaacgtgcccaaaggcacagtggatgagttctcgggggcagagatc
gtggacaagttccgaggagaagaacagttctcctccggacccagttttgaaaccatctct
gctagtggtctgaatgctgccctggcccactacagcccgaccaaggagctgaaccgcaag
ctgtcctcagatgagatgtacctgctggactctggggggcagtactgggacgggaccaca
gacatcaccagaacagtccactggggcaccccctctgccttccagaaggaggcatacacc
cgtgtgctgataggaaatattgacctgtccaggctcatctttcccgctgctacatcaggg
cgaatggtggaggcctttgcccgcagagccttgtgggatgctggtctcaattatggtcat
gggacaggccacggcattggcaacttcctgtgtgtgcatgagtggccagtgggattccag
tccaacaacatcgctatggccaagggcatgttcacttccattgaacctggttactataag
gatggagaatttgggatccgtctcgaagatgtggctctcgtggtagaagcaaagaccaag
tacccagggagctacctgacctttgaagtggtatcatttgtgccctatgaccggaacctc
atcgatgtcagcctgctgtctcccgagcatctccagtacctgaatcgctactaccagacc
atccgggagaaggtgggtccagagctgcagaggcgccagctactagaggagttcgagtgg
cttcaacagcacacagagcccctggccgccagggccccagacaccgcctcctgggcctct
gtgttagtggtctccacccttgccatccttggctggagtgtctag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (50)   

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