KEGG   Homo sapiens (human): 79184
Entry
79184             CDS       T01001                                 
Symbol
BRCC3, BRCC36, C6.1A, CXorf53
Name
(RefSeq) BRCA1/BRCA2-containing complex subunit 3
  KO
K11864  BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03440  Homologous recombination
hsa04621  NOD-like receptor signaling pathway
Network
nt06506  Double-strand break repair
  Element
N01446  DNA end resection and RPA loading
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03440 Homologous recombination
    79184 (BRCC3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    79184 (BRCC3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    79184 (BRCC3)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    79184 (BRCC3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    79184 (BRCC3)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    79184 (BRCC3)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M67
   79184 (BRCC3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   BRCC complex
    79184 (BRCC3)
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   JAMM
    79184 (BRCC3)
   BRISC complex
    79184 (BRCC3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    BRISC complex
     79184 (BRCC3)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    BRCA1-A complex
     79184 (BRCC3)
SSDB
Motif
Pfam: BRCC36_C JAB Prok-JAB UPF0172 DUF6262 TEDC1
Other DBs
NCBI-GeneID: 79184
NCBI-ProteinID: NP_077308
OMIM: 300617
HGNC: 24185
Ensembl: ENSG00000185515
UniProt: P46736
Structure
Position
X:155071508..155123077
AA seq 316 aa
MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMR
TVAEKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGW
YHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQK
SSESLHGPRDFWSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILC
QEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQE
LQQEKEELMQELSSLE
NT seq 951 nt   +upstreamnt  +downstreamnt
atggcggtgcaggtggtgcaggcggtgcaggcggttcatctcgagtctgacgctttcctc
gtttgtctcaaccacgctctgagcacagagaaggaggaagtaatggggctgtgcataggg
gagttgaacgatgatacaaggagtgactccaaatttgcatatactggaactgaaatgcgc
acagttgctgaaaaggttgatgccgtcagaattgttcacattcattctgtcatcatctta
cgacgttctgataagaggaaggaccgagtagaaatttctccagagcagctgtctgcagct
tcaacagaggcagagaggttggctgaactgacaggccgccccatgagagttgtgggctgg
tatcattcccatcctcatataactgtttggccttcacatgttgatgttcgcacacaagcc
atgtaccagatgatggatcaaggctttgtaggacttattttttcctgtttcatagaagat
aagaacacaaagactggccgggtactctacacttgcttccaatccatacaggcccaaaag
agttcagagtcccttcatggtccacgagacttctggagctccagccagcacatctccatt
gagggccagaaggaagaggaaaggtatgagagaatcgaaatcccaatccatattgtacct
catgtcactatcgggaaagtgtgccttgaatcagcagtagagctgcccaagatcctgtgc
caggaggagcaggatgcgtataggaggatccacagccttacacatctggactcagtaacc
aagatccataatggctcagtgtttaccaagaatctgtgcagtcagatgtcggcagtcagc
gggcctctcctacagtggttggaggacagactggagcaaaaccaacagcatttgcaggaa
ttacaacaagaaaaggaagagcttatgcaagaactttcttctctagaataa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
3D Structure (2)   
   PDB (2)   
Protein domain (6)   
   Pfam (6)   
All databases (67)   

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