KEGG   Homo sapiens (human): 79661
Entry
79661             CDS       T01001                                 
Symbol
NEIL1, FPG1, NEI1, hFPG1
Name
(RefSeq) nei like DNA glycosylase 1
  KO
K10567  endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
Network
nt06504  Base excision repair
  Element
N01435  Base excision and strand cleavage by NEIL glycosylase
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    79661 (NEIL1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    79661 (NEIL1)
Enzymes [BR:hsa01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     79661 (NEIL1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA glycosylases
     79661 (NEIL1)
SSDB
Motif
Pfam: Neil1-DNA_bind Fapy_DNA_glyco H2TH
Other DBs
NCBI-GeneID: 79661
NCBI-ProteinID: NP_078884
OMIM: 608844
HGNC: 18448
Ensembl: ENSG00000140398
UniProt: Q96FI4
Structure
Position
15:75347039..75357115
AA seq 390 aa
MPEGPELHLASQFVNEACRALVFGGCVEKSSVSRNPEVPFESSAYRISASARGKELRLIL
SPLPGAQPQQEPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRF
GRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRA
EILYRLKIPPFEKARSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLG
GKGYGSESGEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKS
KATQLSPEDRVEDALPPSKAPSRTRRAKRDLPKRTATQRPEGTSLQQDPEAPTVPKKGRR
KGRQAASGHCRPRKVKADIPSLEPEGTSAS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgcctgagggccccgagctgcacctggccagccagtttgtgaatgaggcctgcagggcg
ctggtgttcggcggctgcgtggagaagtcctctgtcagccgcaaccctgaggtgcccttt
gagagcagtgcctaccgcatctcagcttcagcccgcggcaaggagctgcgcctgatactg
agccctctgcctggggcccagccccaacaggagccactggccctggtcttccgcttcggc
atgtccggctcttttcagctggtgccccgcgaggagctgccacgccatgcccacctgcgc
ttttacacggccccgcctggcccccggctcgccctatgtttcgtggacatccgccggttc
ggccgctgggaccttgggggaaagtggcagccgggccgcgggccctgtgtcttgcaggag
taccagcagttcagggagaatgtgctacgaaacctagcggataaggcctttgaccggccc
atctgcgaggccctcctggaccagaggttcttcaatggcattggcaactatctgcgggca
gagatcctgtaccggctgaagatccccccctttgagaaggcccgctcggtcctggaggcc
ctgcagcagcacaggccgagcccggagctgaccctgagccagaagataaggaccaagctg
cagaatccagacctgctggagctatgtcactcagtgcccaaggaagtggtccagttgggg
ggcaaaggctacgggtcagagagcggggaggaggactttgctgcctttcgagcctggctg
cgctgctatggcatgccaggcatgagctccctgcaggaccggcatggccgtaccatctgg
ttccagggggatcctggaccgttggcacccaaagggcgcaagtcccgcaaaaagaaatcc
aaggccacacagctgagtcctgaggacagagtggaggacgctttgcctccaagcaaggcc
ccttccaggacacgaagggcaaagagagaccttcctaagaggactgcaacccagcggcct
gaggggaccagcctccagcaggacccagaagctcccacagtgcccaagaaggggaggagg
aaggggcgacaggcagcctctggccactgcagaccccggaaggtcaaggctgacatccca
tccttggaaccagaggggacctcagcctcttag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (19)   
   RefSeq(nuc) (5)   
   GenBank (7)   
   EMBL (7)   
3D Structure (27)   
   PDB (27)   
Protein domain (3)   
   Pfam (3)   
All databases (84)   

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