KEGG   Homo sapiens (human): 79726
Entry
79726             CDS       T01001                                 
Symbol
WDR59, CDW12, FP977, p90-120
Name
(RefSeq) WD repeat domain 59
  KO
K20409  SEA/GATOR complex protein SEA3/WDR59
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    79726 (WDR59)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    79726 (WDR59)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   SEACAT/GATOR2 complex
    79726 (WDR59)
SSDB
Motif
Pfam: WD40 zf-RING_16 zinc_ribbon_16 RWD zf-RING_2 MIOS_WD40 zf-rbx1
Other DBs
NCBI-GeneID: 79726
NCBI-ProteinID: NP_085058
OMIM: 617418
HGNC: 25706
Ensembl: ENSG00000103091
UniProt: Q6PJI9
Structure
Position
16:complement(74871362..74985123)
AA seq 974 aa
MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKW
DIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDL
LVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKP
STAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRKYLNILPCQVPVWKA
RYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDY
QLVTWSRDQTLRMWRVDSQMQRLCANDILDGVDEFIESISLLPEPEKTLHTEDTDHQHTA
SHGEEEALKEDPPRNLLEERKSDQLGLPQTLQQEFSLINVQIRNVNVEMDAADRSCTVSV
HCSNHRVKMLVKFPAQYPNNAAPSFQFINPTTITSTMKAKLLKILKDTALQKVKRGQSCL
EPCLRQLVSCLESFVNQEDSASSNPFALPNSVTPPLPTFARVTTAYGSYQDANIPFPRTS
GARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLY
SGSPTRSEKEQVSISSFYYKERKSRRWKSKREGSDSGNRQIKAAGKVIIQDIACLLPVHK
SLGELYILNVNDIQETCQKNAASALLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWA
RHPFGRQLLESLLAHYCRLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHS
RYPSFTSSGSCSSMSDPGLNTGGWNIAGREAEHLSSPWGESSPEELRFGSLTYSDPRERE
RDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPDPHKGIEFGV
YCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVC
PTGCGCHCLLESTF
NT seq 2925 nt   +upstreamnt  +downstreamnt
atggcggcgcgatggagcagcgaaaacgtggttgtagagttccgtgactcccaggcaact
gcgatgtctgtggactgtcttgggcagcatgcagtgctttctggccgcagattcttatac
atcgtcaatctagatgcccctttcgaaggtcaccgaaagatctctcgccagagcaaatgg
gacattggagctgtgcagtggaatcctcatgacagctttgcacactattttgcggcttcg
agtaaccaacgagtagacctttacaagtggaaagacggcagtggggaagttggcacaacc
ttacaaggccacactcgtgtcatcagcgacttggactgggcggtgtttgagcctgacctc
ctggttaccagctctgtggacacctacatctacatttgggatatcaaagacacaaggaaa
cctactgttgcactgtctgctgttgcgggtgcctcccaggtcaaatggaataaaaaaaat
gctaactgccttgccaccagccatgacggcgatgtgcggatatgggataagaggaaaccc
agtacagcagtggaatatctagccgcccacctctccaaaatccatggcctggactggcac
ccagacagcgagcacattcttgctacctccagtcaagacaattctgtgaagttctgggat
taccgccagcctcggaaatacctcaatattcttccttgccaggtgcctgtctggaaggcc
agatacacacctttcagcaatggattggtgactgtgatggttccccagctgcggagggaa
aacagccttctcctgtggaatgtctttgacttgaacaccccagtccacaccttcgtgggg
catgatgatgtggtcctggagttccagtggaggaagcagaaggaagggtccaaggactat
caactggtgacgtggtcccgggatcagaccttgagaatgtggcgggtggattcccagatg
cagaggctttgtgcaaatgacatattagatggtgttgatgagttcattgagagtatttcc
cttctgccggaacctgagaagaccctgcacactgaagatacagatcaccagcacactgca
agccatggggaggaagaagccctaaaagaagatccccctagaaatctcctggaagagagg
aaatcagatcaactggggctgcctcagaccttgcagcaggaattctccctgatcaatgtg
caaatccggaatgtcaatgtggagatggatgcggcagacaggagctgcacagtgtctgtg
cactgcagcaaccatcgtgtcaagatgctggtgaagttccctgcacagtacccaaacaac
gccgccccttccttccagtttattaaccccacaaccatcacatccaccatgaaagctaag
ctgctgaagatcctgaaggacacagccctgcagaaagtgaagcgtggccagagctgcctg
gagccctgcctgcgccagctcgtctcctgccttgagtcctttgtgaaccaggaagacagc
gcttccagcaacccgtttgcactccccaactctgtcactccccccttaccgacgtttgcg
cgggtgaccacggcttacgggtcgtaccaggacgccaacattccctttcctaggacttct
ggggccaggttctgcggagcaggttacctggtatatttcacaaggcccatgacaatgcat
cgggcggtgtctcccacagagcctactccgagatctctctcagccttgtctgcttatcac
actggcttgatcgcgcccatgaagatccgcacagaggcccctgggaaccttcgtttatac
agtgggagccccactcgcagcgagaaagagcaggtctccatcagctccttctactacaag
gagcggaaatcaagacgatggaaaagtaagcgtgagggatcagactctggcaatcgacag
atcaaggctgctgggaaagtcatcatccaggatattgcttgcctcctgcctgttcacaaa
tcgctgggagagctgtacatattgaatgtgaatgatattcaggaaacatgtcagaagaat
gccgcctctgccttgctcgttggaagaaaggatcttgtccaggtttggtcgctggctacg
gtagctacagatctttgccttggtccgaaatctgacccagatttggaaacaccctgggct
cgacatccatttgggcggcagctgctggagtccctgttggctcactattgccggctccgg
gatgttcagacactggcgatgctctgtagcgtgtttgaagcccagtctcggcctcagggg
ctaccaaacccctttgggccttttcctaaccgttcttctaatcttgtggtgtcccatagt
cgatatcctagctttacctcttctggttcctgctccagtatgtcagacccagggctcaac
actggcggctggaacatagcgggaagagaggcagagcacttgtcctccccttggggagaa
tcctcaccagaagagctccgctttgggagtctgacctacagtgatccccgtgagcgagaa
cgcgaccagcatgataaaaataaaaggctcctggaccccgccaatacccagcaatttgat
gactttaagaaatgctatggggaaatcctctaccgttggggtctgagagagaagcgagct
gaagtgttgaagtttgtctcctgtcctcctgaccctcacaaagggatcgagttcggcgtg
tactgcagccactgccggagtgaggtccgtggcacgcagtgtgccatctgcaaaggcttc
acgttccagtgtgccatctgtcacgtggctgtgcggggatcgtccaatttctgcctgacc
tgtgggcacggtggccacaccagccacatgatggagtggtttcggacccaggaggtgtgt
cccaccgggtgtgggtgccactgcctgcttgaaagcactttctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (49)   
   RefSeq(nuc) (25)   
   GenBank (12)   
   EMBL (12)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (111)   

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