KEGG   Homo sapiens (human): 80271
Entry
80271             CDS       T01001                                 
Symbol
ITPKC, IP3-3KC, IP3KC
Name
(RefSeq) inositol-trisphosphate 3-kinase C
  KO
K00911  1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04020  Calcium signaling pathway
hsa04070  Phosphatidylinositol signaling system
Module
hsa_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    80271 (ITPKC)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    80271 (ITPKC)
   04070 Phosphatidylinositol signaling system
    80271 (ITPKC)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.127  inositol-trisphosphate 3-kinase
     80271 (ITPKC)
SSDB
Motif
Pfam: IPK
Other DBs
NCBI-GeneID: 80271
NCBI-ProteinID: NP_079470
OMIM: 606476
HGNC: 14897
Ensembl: ENSG00000086544
UniProt: Q96DU7
Structure
Position
19:40717112..40740860
AA seq 683 aa
MRRCPCRGSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWA
RTEGSSLHSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTEPDRSSL
RTHLEWSWSELETTCLWTETGTDGLWTDPHRSDLQFQPEEASPWTQPGVHGPWTELETHG
SQTQPERVKSWADNLWTHQNSSSLQTHPEGACPSKEPSADGSWKELYTDGSRTQQDIEGP
WTEPYTDGSQKKQDTEAARKQPGTGGFQIQQDTDGSWTQPSTDGSQTAPGTDCLLGEPED
GPLEEPEPGELLTHLYSHLKCSPLCPVPRLIITPETPEPEAQPVGPPSRVEGGSGGFSSA
SSFDESEDDVVAGGGGASDPEDRSGSKPWKKLKTVLKYSPFVVSFRKHYPWVQLSGHAGN
FQAGEDGRILKRFCQCEQRSLEQLMKDPLRPFVPAYYGMVLQDGQTFNQMEDLLADFEGP
SIMDCKMGSRTYLEEELVKARERPRPRKDMYEKMVAVDPGAPTPEEHAQGAVTKPRYMQW
RETMSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVDGDHVILQKYVACLE
ELREALEISPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQTLSHRLPWAEG
NREDGYLWGLDNMICLLQGLAQS
NT seq 2052 nt   +upstreamnt  +downstreamnt
atgaggcgctgcccgtgccgtgggagcctgaacgaggcggaggccggggcgctgcccgcg
gcggcccgcatgggactggaggcgccgcgaggagggcggcggcggcagccgggacagcag
cgacctgggcccggcgcaggggccccggcggggcggccggaggggggcgggccctgggcc
cggacagaggggtccagcctccacagcgagcctgagagggccggcctcgggcctgcgccg
gggacagagagtccgcaggcagaattctggacagacggacagactgagcccgcggcagct
ggccttggagtagagaccgagaggcccaagcaaaagacggagccagacaggtccagcctc
cggacgcatctagaatggagctggtcagagctggagacgacttgtctttggacggagacc
gggacagatggcctttggactgatccgcacaggtccgacctccagtttcagcccgaggag
gccagcccctggacacagccaggggttcatgggccctggacagagctggaaacgcatggg
tcacagactcagccagagagggtcaagtcctgggctgataacctctggacccaccagaac
agttccagcctccagactcacccagaaggagcctgtccctcaaaagagccaagtgctgat
ggctcctggaaagaattgtatactgatggctccaggacacaacaggatattgaaggtccc
tggacagagccatatactgatggctcccagaaaaaacaggatactgaagcagccaggaaa
cagcctggcactggtggtttccaaatacaacaggatactgatggctcctggacacaacct
agcactgacggttcccagacagcacctgggacagactgcctcttgggagagcctgaggat
ggcccattagaggaaccagagcctggagaattgctgactcacctgtactctcacctgaag
tgtagccccctgtgccctgtgccccgcctcatcattacccctgagacccctgagcctgag
gcccagccagtgggacccccctcccgggttgaggggggcagcggcggcttctcctctgcc
tcttctttcgacgagtctgaggatgacgtggtggccgggggcggaggtgccagcgatccc
gaggacaggtctgggagcaaaccctggaagaagctgaagacagttctgaagtattcaccc
tttgtggtctccttccgaaaacactacccttgggtccagctttctggacatgctgggaac
ttccaggcaggagaggatggtcggattctgaaacgtttctgtcagtgtgagcagcgcagc
ctggagcagctgatgaaagacccgctgcgacctttcgtgcctgcctactatggcatggtg
ctgcaggatggccagaccttcaaccagatggaagacctcctggctgactttgagggcccc
tccattatggactgcaagatgggcagcaggacctatctggaagaggagctagtgaaggca
cgggaacgtccccgtccccggaaggacatgtatgagaagatggtggctgtggaccctggg
gcccctacccctgaggagcatgcccagggtgcagtcaccaagccccgctacatgcagtgg
agggaaaccatgagctccacctctaccctgggcttccggatcgagggcatcaagaaggca
gatgggacctgtaacaccaacttcaagaagacgcaggcactggagcaggtgacaaaagtg
ctggaggacttcgtggatggagaccacgtcatcctgcaaaagtacgtggcatgcctagaa
gaacttcgtgaagctctggagatctcccccttcttcaagacccacgaggtggtaggcagc
tccctcctcttcgtgcacgaccacaccggcctggccaaggtctggatgatagacttcggc
aagacggtggccttgcccgaccaccagacgctcagccacaggctgccctgggctgagggc
aaccgtgaggacggctacctctggggcctggacaacatgatctgcctcctgcaggggctg
gcacagagctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (17)   
   RefSeq(nuc) (5)   
   GenBank (6)   
   EMBL (6)   
3D Structure (1)   
   PDB (1)   
Protein domain (1)   
   Pfam (1)   
All databases (78)   

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