KEGG   Homo sapiens (human): 80312
Entry
80312             CDS       T01001                                 
Symbol
TET1, CXXC6, LCX, bA119F7.1
Name
(RefSeq) tet methylcytosine dioxygenase 1
  KO
K13097  methylcytosine dioxygenase [EC:1.14.11.80]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    80312 (TET1)
   03041 Spliceosome [BR:hsa03041]
    80312 (TET1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.80  methylcytosine dioxygenase
     80312 (TET1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    80312 (TET1)
Spliceosome [BR:hsa03041]
 Complex A
  Other components
   Complex A specific factors
    80312 (TET1)
SSDB
Motif
Pfam: Tet_JBP zf-CXXC
Other DBs
NCBI-GeneID: 80312
NCBI-ProteinID: NP_085128
OMIM: 607790
HGNC: 29484
Ensembl: ENSG00000138336
UniProt: Q8NFU7
Structure
Position
10:68560337..68694487
AA seq 2136 aa
MSRSRHARPSRLVRKEDVNKKKKNSQLRKTTKGANKNVASVKTLSPGKLKQLIQERDVKK
KTEPKPPVPVRSLLTRAGAARMNLDRTEVLFQNPESLTCNGFTMALRSTSLSRRLSQPPL
VVAKSKKVPLSKGLEKQHDCDYKILPALGVKHSENDSVPMQDTQVLPDIETLIGVQNPSL
LKGKSQETTQFWSQRVEDSKINIPTHSGPAAEILPGPLEGTRCGEGLFSEETLNDTSGSP
KMFAQDTVCAPFPQRATPKVTSQGNPSIQLEELGSRVESLKLSDSYLDPIKSEHDCYPTS
SLNKVIPDLNLRNCLALGGSTSPTSVIKFLLAGSKQATLGAKPDHQEAFEATANQQEVSD
TTSFLGQAFGAIPHQWELPGADPVHGEALGETPDLPEIPGAIPVQGEVFGTILDQQETLG
MSGSVVPDLPVFLPVPPNPIATFNAPSKWPEPQSTVSYGLAVQGAIQILPLGSGHTPQSS
SNSEKNSLPPVMAISNVENEKQVHISFLPANTQGFPLAPERGLFHASLGIAQLSQAGPSK
SDRGSSQVSVTSTVHVVNTTVVTMPVPMVSTSSSSYTTLLPTLEKKKRKRCGVCEPCQQK
TNCGECTYCKNRKNSHQICKKRKCEELKKKPSVVVPLEVIKENKRPQREKKPKVLKADFD
NKPVNGPKSESMDYSRCGHGEEQKLELNPHTVENVTKNEDSMTGIEVEKWTQNKKSQLTD
HVKGDFSANVPEAEKSKNSEVDKKRTKSPKLFVQTVRNGIKHVHCLPAETNVSFKKFNIE
EFGKTLENNSYKFLKDTANHKNAMSSVATDMSCDHLKGRSNVLVFQQPGFNCSSIPHSSH
SIINHHASIHNEGDQPKTPENIPSKEPKDGSPVQPSLLSLMKDRRLTLEQVVAIEALTQL
SEAPSENSSPSKSEKDEESEQRTASLLNSCKAILYTVRKDLQDPNLQGEPPKLNHCPSLE
KQSSCNTVVFNGQTTTLSNSHINSATNQASTKSHEYSKVTNSLSLFIPKSNSSKIDTNKS
IAQGIITLDNCSNDLHQLPPRNNEVEYCNQLLDSSKKLDSDDLSCQDATHTQIEEDVATQ
LTQLASIIKINYIKPEDKKVESTPTSLVTCNVQQKYNQEKGTIQQKPPSSVHNNHGSSLT
KQKNPTQKKTKSTPSRDRRKKKPTVVSYQENDRQKWEKLSYMYGTICDIWIASKFQNFGQ
FCPHDFPTVFGKISSSTKIWKPLAQTRSIMQPKTVFPPLTQIKLQRYPESAEEKVKVEPL
DSLSLFHLKTESNGKAFTDKAYNSQVQLTVNANQKAHPLTQPSSPPNQCANVMAGDDQIR
FQQVVKEQLMHQRLPTLPGISHETPLPESALTLRNVNVVCSGGITVVSTKSEEEVCSSSF
GTSEFSTVDSAQKNFNDYAMNFFTNPTKNLVSITKDSELPTCSCLDRVIQKDKGPYYTHL
GAGPSVAAVREIMENRYGQKGNAIRIEIVVYTGKEGKSSHGCPIAKWVLRRSSDEEKVLC
LVRQRTGHHCPTAVMVVLIMVWDGIPLPMADRLYTELTENLKSYNGHPTDRRCTLNENRT
CTCQGIDPETCGASFSFGCSWSMYFNGCKFGRSPSPRRFRIDPSSPLHEKNLEDNLQSLA
TRLAPIYKQYAPVAYQNQVEYENVARECRLGSKEGRPFSGVTACLDFCAHPHRDIHNMNN
GSTVVCTLTREDNRSLGVIPQDEQLHVLPLYKLSDTDEFGSKEGMEAKIKSGAIEVLAPR
RKKRTCFTQPVPRSGKKRAAMMTEVLAHKIRAVEKKPIPRIKRKNNSTTTNNSKPSSLPT
LGSNTETVQPEVKSETEPHFILKSSDNTKTYSLMPSAPHPVKEASPGFSWSPKTASATPA
PLKNDATASCGFSERSSTPHCTMPSGRLSGANAAAADGPGISQLGEVAPLPTLSAPVMEP
LINSEPSTGVTEPLTPHQPNHQPSFLTSPQDLASSPMEEDEQHSEADEPPSDEPLSDDPL
SPAEEKLPHIDEYWSDSEHIFLDANIGGVAIAPAHGSVLIECARRELHATTPVEHPNRNH
PTRLSLVFYQHKNLNKPQHGFELNKIKFEAKEAKNKKMKASEQKDQAANEGPEQSSEVNE
LNQIPSHKALTLTHDNVVTVSPYALTHVAGPYNHWV
NT seq 6411 nt   +upstreamnt  +downstreamnt
atgtctcgatcccgccatgcaaggccttccagattagtcaggaaggaagatgtaaacaaa
aaaaagaaaaacagccaactacgaaagacaaccaagggagccaacaaaaatgtggcatca
gtcaagactttaagccctggaaaattaaagcaattaattcaagaaagagatgttaagaaa
aaaacagaacctaaaccacccgtgccagtcagaagccttctgacaagagctggagcagca
cgcatgaatttggataggactgaggttctttttcagaacccagagtccttaacctgcaat
gggtttacaatggcgctacgaagcacctctcttagcaggcgactctcccaacccccactg
gtcgtagccaaatccaaaaaggttccactttctaagggtttagaaaagcaacatgattgt
gattataagatactccctgctttgggagtaaagcactcagaaaatgattcggttccaatg
caagacacccaagtccttcctgatatagagactctaattggtgtacaaaatccctcttta
cttaaaggtaagagccaagagacaactcagttttggtcccaaagagttgaggattccaag
atcaatatccctacccacagtggccctgcagctgagatccttcctgggccactggaaggg
acacgctgtggtgaaggactattctctgaagagacattgaatgataccagtggttcccca
aaaatgtttgctcaggacacagtgtgtgctccttttccccaaagagcaacccccaaagtt
acctctcaaggaaaccccagcattcagttagaagagttgggttcacgagtagaatctctt
aagttatctgattcttacctggatcccattaaaagtgaacatgattgctaccccacctcc
agtcttaataaggttatacctgacttgaaccttagaaactgcttggctcttggtgggtct
acgtctcctacctctgtaataaaattcctcttggcaggctcaaaacaagcgacccttggt
gctaaaccagatcatcaagaggccttcgaagctactgcaaatcaacaggaagtttctgat
accacctctttcctaggacaggcctttggtgctatcccacatcaatgggaacttcctggt
gctgacccagttcatggtgaggccctgggtgagaccccagatctaccagagattcctggt
gctattccagtccaaggagaggtctttggtactattttagaccaacaagaaactcttggt
atgagtgggagtgttgtcccagacttgcctgtcttccttcctgttcctccaaatccaatt
gctacctttaatgctccttccaaatggcctgagccccaaagcactgtctcatatggactt
gcagtccagggtgctatacagattttgcctttgggctcaggacacactcctcaatcatca
tcaaactcagagaaaaattcattacctccagtaatggctataagcaatgtagaaaatgag
aagcaggttcatataagcttcctgccagctaacactcaggggttcccattagcccctgag
agaggactcttccatgcttcactgggtatagcccaactctctcaggctggtcctagcaaa
tcagacagagggagctcccaggtcagtgtaaccagcacagttcatgttgtcaacaccaca
gtggtgactatgccagtgccaatggtcagtacctcctcttcttcctataccactttgcta
ccgactttggaaaagaagaaaagaaagcgatgtggggtctgtgaaccctgccagcagaag
accaactgtggtgaatgcacttactgcaagaacagaaagaacagccatcagatctgtaag
aaaagaaaatgtgaggagctgaaaaagaaaccatctgttgttgtgcctctggaggttata
aaggaaaacaagaggccccagagggaaaagaagcccaaagttttaaaggcagattttgac
aacaaaccagtaaatggccccaagtcagaatccatggactacagtagatgtggtcatggg
gaagaacaaaaattggaattgaacccacatactgttgaaaatgtaactaaaaatgaagac
agcatgacaggcatcgaggtggagaagtggacacaaaacaagaaatcacagttaactgat
cacgtgaaaggagattttagtgctaatgtcccagaagctgaaaaatcgaaaaactctgaa
gttgacaagaaacgaaccaaatctccaaaattgtttgtacaaaccgtaagaaatggcatt
aaacatgtacactgtttaccagctgaaacaaatgtttcatttaaaaaattcaatattgaa
gaattcggcaagacattggaaaacaattcttataaattcctaaaagacactgcaaaccat
aaaaacgctatgagctctgttgctactgatatgagttgtgatcatctcaaggggagaagt
aacgttttagtattccagcagcctggctttaactgcagttccattccacattcttcacac
tccatcataaatcatcatgctagtatacacaatgaaggtgatcaaccaaaaactcctgag
aatataccaagtaaagaaccaaaagatggatctcccgttcaaccaagtctcttatcgtta
atgaaagataggagattaacattggagcaagtggtagccatagaggccctgactcaactc
tcagaagccccatcagagaattcctccccatcaaagtcagagaaggatgaggaatcagag
cagagaacagccagtttgcttaatagctgcaaagctatcctctacactgtaagaaaagac
ctccaagacccaaacttacagggagagccaccaaaacttaatcactgtccatctttggaa
aaacaaagttcatgcaacacggtggttttcaatgggcaaactactaccctttccaactca
catatcaactcagctactaaccaagcatccacaaagtcacatgaatattcaaaagtcaca
aattcattatctctttttataccaaaatcaaattcatccaagattgacaccaataaaagt
attgctcaagggataattactcttgacaattgttccaatgatttgcatcagttgccacca
agaaataatgaagtggagtattgcaaccagttactggacagcagcaaaaaattggactca
gatgatctatcatgtcaggatgcaacccatacccaaattgaggaagatgttgcaacacag
ttgacacaacttgcttcgataattaagatcaattatataaaaccagaggacaaaaaagtt
gaaagtacaccaacaagccttgtcacatgtaatgtacagcaaaaatacaatcaggagaag
ggcacaatacaacagaaaccaccttcaagtgtacacaataatcatggttcatcattaaca
aaacaaaagaacccaacccagaaaaagacaaaatccaccccatcaagagatcggcggaaa
aagaagcccacagttgtaagttatcaagaaaatgatcggcagaagtgggaaaagttgtcc
tatatgtatggcacaatatgcgacatttggatagcatcgaaatttcaaaattttgggcaa
ttttgtccacatgattttcctactgtatttgggaaaatttcttcctcgaccaaaatatgg
aaaccactggctcaaacgaggtccattatgcaacccaaaacagtatttccaccactcact
cagataaaattacagagatatcctgaatcagcagaggaaaaggtgaaggttgaaccattg
gattcactcagcttatttcatcttaaaacggaatccaacgggaaggcattcactgataaa
gcttataattctcaggtacagttaacggtgaatgccaatcagaaagcccatcctttgacc
cagccctcctctccacctaaccagtgtgctaacgtgatggcaggcgatgaccaaatacgg
tttcagcaggttgttaaggagcaactcatgcatcagagactgccaacattgcctggtatc
tctcatgaaacacccttaccggagtcagcactaactctcaggaatgtaaatgtagtgtgt
tcaggtggaattacagtggtttctaccaaaagtgaagaggaagtctgttcatccagtttt
ggaacatcagaattttccacagtggacagtgcacagaaaaattttaatgattatgccatg
aacttctttactaaccctacaaaaaacctagtgtctataactaaagattctgaactgccc
acctgcagctgtcttgatcgagttatacaaaaagacaaaggcccatattatacacacctt
ggggcaggaccaagtgttgctgctgtcagggaaatcatggagaataggtatggtcaaaaa
ggaaacgcaataaggatagaaatagtagtgtacaccggtaaagaagggaaaagctctcat
gggtgtccaattgctaagtgggttttaagaagaagcagtgatgaagaaaaagttctttgt
ttggtccggcagcgtacaggccaccactgtccaactgctgtgatggtggtgctcatcatg
gtgtgggatggcatccctcttccaatggccgaccggctatacacagagctcacagagaat
ctaaagtcatacaatgggcaccctaccgacagaagatgcaccctcaatgaaaatcgtacc
tgtacatgtcaaggaattgatccagagacttgtggagcttcattctcttttggctgttca
tggagtatgtactttaatggctgtaagtttggtagaagcccaagccccagaagatttaga
attgatccaagctctcccttacatgaaaaaaaccttgaagataacttacagagtttggct
acacgattagctccaatttataagcagtatgctccagtagcttaccaaaatcaggtggaa
tatgaaaatgttgcccgagaatgtcggcttggcagcaaggaaggtcgtcccttctctggg
gtcactgcttgcctggacttctgtgctcatccccacagggacattcacaacatgaataat
ggaagcactgtggtttgtaccttaactcgagaagataaccgctctttgggtgttattcct
caagatgagcagctccatgtgctacctctttataagctttcagacacagatgagtttggc
tccaaggaaggaatggaagccaagatcaaatctggggccatcgaggtcctggcaccccgc
cgcaaaaaaagaacgtgtttcactcagcctgttccccgttctggaaagaagagggctgcg
atgatgacagaggttcttgcacataagataagggcagtggaaaagaaacctattccccga
atcaagcggaagaataactcaacaacaacaaacaacagtaagccttcgtcactgccaacc
ttagggagtaacactgagaccgtgcaacctgaagtaaaaagtgaaaccgaaccccatttt
atcttaaaaagttcagacaacactaaaacttattcgctgatgccatccgctcctcaccca
gtgaaagaggcatctccaggcttctcctggtccccgaagactgcttcagccacaccagct
ccactgaagaatgacgcaacagcctcatgcgggttttcagaaagaagcagcactccccac
tgtacgatgccttcgggaagactcagtggtgccaatgcagctgctgctgatggccctggc
atttcacagcttggcgaagtggctcctctccccaccctgtctgctcctgtgatggagccc
ctcattaattctgagccttccactggtgtgactgagccgctaacgcctcatcagccaaac
caccagccctccttcctcacctctcctcaagaccttgcctcttctccaatggaagaagat
gagcagcattctgaagcagatgagcctccatcagacgaacccctatctgatgaccccctg
tcacctgctgaggagaaattgccccacattgatgagtattggtcagacagtgagcacatc
tttttggatgcaaatattggtggggtggccatcgcacctgctcacggctcggttttgatt
gagtgtgcccggcgagagctgcacgctaccactcctgttgagcaccccaaccgtaatcat
ccaacccgcctctcccttgtcttttaccagcacaaaaacctaaataagccccaacatggt
tttgaactaaacaagattaagtttgaggctaaagaagctaagaataagaaaatgaaggcc
tcagagcaaaaagaccaggcagctaatgaaggtccagaacagtcctctgaagtaaatgaa
ttgaaccaaattccttctcataaagcattaacattaacccatgacaatgttgtcaccgtg
tccccttatgctctcacacacgttgcggggccctataaccattgggtctga

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (45)   
   KEGG ORTHOLOGY (1)   
   RefGene (38)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (51)   
   RefSeq(nuc) (25)   
   GenBank (13)   
   EMBL (13)   
3D Structure (1)   
   PDB (1)   
Protein domain (2)   
   Pfam (2)   
All databases (134)   

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