KEGG   Homo sapiens (human): 80381
Entry
80381             CDS       T01001                                 
Symbol
CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2
Name
(RefSeq) CD276 molecule
  KO
K06746  immune costimulatory protein B7-H3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04514  Cell adhesion molecules
Drug target
Enoblituzumab: D11752
Ifinatamab deruxtecan: D12753
Mirzotamab: D12154
Omburtamab: D11515
Vobramitamab: D12517
Voramitamab duocarmazine: D12518
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    80381 (CD276)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    80381 (CD276)
CD molecules [BR:hsa04090]
 Proteins
  80381 (CD276)
SSDB
Motif
Pfam: Ig_3 ig Ig_2 V-set I-set C2-set_2 C1-set
Other DBs
NCBI-GeneID: 80381
NCBI-ProteinID: NP_001019907
OMIM: 605715
HGNC: 19137
Ensembl: ENSG00000103855
UniProt: Q5ZPR3
Position
15:73683944..73714514
AA seq 534 aa
MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD
GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ
RSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEG
RDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY
SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF
DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIAL
LVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgctgcgtcggcggggcagccctggcatgggtgtgcatgtgggtgcagccctgggagca
ctgtggttctgcctcacaggagccctggaggtccaggtccctgaagacccagtggtggca
ctggtgggcaccgatgccaccctgtgctgctccttctcccctgagcctggcttcagcctg
gcacagctcaacctcatctggcagctgacagataccaaacagctggtgcacagctttgct
gagggccaggaccagggcagcgcctatgccaaccgcacggccctcttcccggacctgctg
gcacagggcaacgcatccctgaggctgcagcgcgtgcgtgtggcggacgagggcagcttc
acctgcttcgtgagcatccgggatttcggcagcgctgccgtcagcctgcaggtggccgct
ccctactcgaagcccagcatgaccctggagcccaacaaggacctgcggccaggggacacg
gtgaccatcacgtgctccagctaccagggctaccctgaggctgaggtgttctggcaggat
gggcagggtgtgcccctgactggcaacgtgaccacgtcgcagatggccaacgagcagggc
ttgtttgatgtgcacagcatcctgcgggtggtgctgggtgcaaatggcacctacagctgc
ctggtgcgcaaccccgtgctgcagcaggatgcgcacagctctgtcaccatcacaccccag
agaagccccacaggagccgtggaggtccaggtccctgaggacccggtggtggccctagtg
ggcaccgatgccaccctgcgctgctccttctcccccgagcctggcttcagcctggcacag
ctcaacctcatctggcagctgacagacaccaaacagctggtgcacagtttcaccgaaggc
cgggaccagggcagcgcctatgccaaccgcacggccctcttcccggacctgctggcacaa
ggcaatgcatccctgaggctgcagcgcgtgcgtgtggcggacgagggcagcttcacctgc
ttcgtgagcatccgggatttcggcagcgctgccgtcagcctgcaggtggccgctccctac
tcgaagcccagcatgaccctggagcccaacaaggacctgcggccaggggacacggtgacc
atcacgtgctccagctaccggggctaccctgaggctgaggtgttctggcaggatgggcag
ggtgtgcccctgactggcaacgtgaccacgtcgcagatggccaacgagcagggcttgttt
gatgtgcacagcgtcctgcgggtggtgctgggtgcgaatggcacctacagctgcctggtg
cgcaaccccgtgctgcagcaggatgcgcacggctctgtcaccatcacagggcagcctatg
acattccccccagaggccctgtgggtgaccgtggggctgtctgtctgtctcattgcactg
ctggtggccctggctttcgtgtgctggagaaagatcaaacagagctgtgaggaggagaat
gcaggagctgaggaccaggatggggagggagaaggctccaagacagccctgcagcctctg
aaacactctgacagcaaagaagatgatggacaagaaatagcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (6)   
   KEGG DRUG (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (20)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (50)   
   RefSeq(nuc) (14)   
   GenBank (18)   
   EMBL (18)   
Protein domain (7)   
   Pfam (7)   
All databases (111)   

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