KEGG   Homo sapiens (human): 80853
Entry
80853             CDS       T01001                                 
Symbol
KDM7A, JHDM1D
Name
(RefSeq) lysine demethylase 7A
  KO
K11445  [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65 1.14.11.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    80853 (KDM7A)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.65  [histone H3]-dimethyl-L-lysine9 demethylase
     80853 (KDM7A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    80853 (KDM7A)
SSDB
Motif
Pfam: JHD JmjC Cupin_8 PHD ASH2L-like_WH PHD_5 JmjC_2 PHD_4
Other DBs
NCBI-GeneID: 80853
NCBI-ProteinID: NP_085150
OMIM: 619640
HGNC: 22224
Ensembl: ENSG00000006459
UniProt: Q6ZMT4
Structure
Position
7:complement(140084746..140176983)
AA seq 941 aa
MAGAAAAVAAGAAAGAAAAAVSVAAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKD
WFHGSCVGVEEHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTEIDDGSKPVQAGTR
TFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPTFSVM
DVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMSELVE
VPDIAKKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLWGEKI
FYLIKPTDENLARYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAVLTSQ
DCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKELRED
GFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIEEENG
KPVKSQGIPIVCPVSRSSNEATSPYHSRRKMRKLRDHNVRTPSNLDILELHTREVLKRLE
MCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQPFADQSLY
TADSENEEDKRRTKKAKMKIEESSGVEGVEHEESQKPLNGFFTRVKSELRSRSSGYSDIS
ESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRNFLQKSQKPSRSEIPI
KRECPTSTSTEEEAIQGMLSMAGLHYSTCLQRQIQSTDCSGERNSLQDPSSCHGSNHEVR
QLYRYDKPVECGYHVKTEDPDLRTSSWIKQFDTSRFHPQDLSRSQKCIRKEGSSEISQRV
QSRNYVDSSGSSLQNGKYMQNSNLTSGACQISNGSLSPERPVGETSFSVPLHPTKRPASN
PPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV
NT seq 2826 nt   +upstreamnt  +downstreamnt
atggccggagcggcggcggcggtggccgcgggagcagcagctggagccgccgcggcagcc
gtgtcggtggcggctcccggccgggcctcggcgcctccgccgcccccgcccgtgtactgt
gtgtgccggcagccgtacgacgtgaaccgcttcatgatcgagtgcgatatctgcaaggac
tggttccacggcagctgtgttggagtagaagaacatcatgctgttgacattgacctgtat
cactgtcccaactgtgcagttttacatggttcctccttgatgaaaaaaaggaggaactgg
cacagacatgactacacagaaattgatgatggttccaaaccagtgcaagctggaactaga
actttcattaaggaattacgctctcgagtcttcccaagtgccgatgaaataattataaag
atgcatggcagccagctgacacaaagatatctggagaaacatggatttgatgtccctatt
atggtcccaaaattagatgatctaggactcaggctcccttcacctacattttctgtgatg
gatgtggaacgttatgtaggtggtgacaaagtgatagatgtcattgatgtggcgaggcag
gcagacagcaaaatgacacttcacaattatgttaaatacttcatgaatcctaacagacca
aaagtgttaaatgtgatcagccttgaattttcagatacaaagatgtctgaattggtggag
gtccctgatatagccaaaaaactttcctgggtggaaaattattggccagatgattcagtc
tttcccaagccatttgttcagaaatattgcttaatgggagttcaagacagctatacagat
ttccacattgacttcggtggaacttcagtctggtaccatgtcctctggggtgagaagatt
ttttatttaataaagccaacagatgaaaatttggcacgttatgaatcttggagttcatct
gtgacccagagtgaggtgttctttggagataaggtggataaatgctacaaatgtgtggta
aagcagggacataccttatttgttcctacagggtggatccatgctgtgctcacttctcag
gactgtatggcttttggggggaacttcctgcacaaccttaacattggcatgcagctcagg
tgttatgagatggagaaaaggctaaaaacaccagatcttttcaaattccctttctttgaa
gccatatgttggtttgtagccaaaaacttgctggaaaccctgaaagaactgagagaagat
ggtttccagcctcaaacttacctagtacagggagtgaaagcactgcatactgctttaaaa
ttatggatgaaaaaagaacttgtatctgaacatgcctttgaaattccagacaatgttaga
cctggacaccttattaaagaactttctaaagtaattcgagcaatagaggaggaaaacggc
aaaccagttaaatctcagggaattcctattgtgtgtccagtttcacgatcctcaaatgaa
gcaacttccccataccattcccgaagaaagatgaggaaacttcgagatcataatgtccga
actccttctaacctagacatcctagagctccacacaagggaggtcctcaaaagattagag
atgtgtccatgggaagaggacatcttgagctctaaactgaatggaaaattcaacaaacat
ctccaaccatcctccacagtacctgaatggagagcgaaagataatgatctacgattactg
ctgacaaatggaagaataattaaagatgaaaggcagccctttgcagatcaaagtctttat
acagcagatagtgaaaatgaagaggataaaagaaggacaaaaaaggcaaaaatgaagata
gaagagagttcaggagtagagggagtggaacatgaagaatctcaaaaaccactgaatggg
ttttttacacgtgtgaaatcagaactcaggagtagatcatcaggatattctgatatttct
gagtcagaagactccggacccgagtgcactgcactgaaaagtatctttaccactgaagag
tctgaaagttcaggtgatgaaaagaaacaagaaataacatccaactttaaggaggaatct
aatgtgatgaggaacttccttcaaaagagccagaagccatctagaagtgaaattccaatt
aaaagggaatgtcctacctcgacgagcacagaggaagaagctattcagggcatgctgtct
atggcagggttgcactattccacgtgtttacaaaggcaaatacaaagcacagactgcagt
ggtgaaagaaactctctccaggatcccagcagctgccatggcagtaaccatgaggttagg
cagttgtatcgctatgataaaccagtggaatgtggataccatgtcaagactgaagatcca
gacttgaggacttcctcctggattaaacagtttgatacttccagatttcatcctcaggat
ctaagtagaagccagaaatgcatcagaaaggaaggttcatcagaaattagtcagagggta
caaagtaggaattatgtggacagcagcggctcaagccttcagaatggaaagtatatgcag
aattcaaacctgacttcgggggcgtgccagataagtaatggcagtctaagcccagaaagg
ccagttggtgaaacttccttctcggtgccccttcaccccaccaagagaccggcatcaaat
ccaccacctatcagcaaccaggcaacaaaaggtaaacgtccaaaaaaaggaatggcaaca
gccaaacaacgtcttgggaagatccttaagttgaacagaaatggccatgcacgtttcttt
gtgtga

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Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (17)   
   RefSeq(nuc) (5)   
   GenBank (6)   
   EMBL (6)   
3D Structure (6)   
   PDB (6)   
Protein domain (8)   
   Pfam (8)   
All databases (60)   

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