KEGG   Homo sapiens (human): 811
Entry
811               CDS       T01001                                 
Symbol
CALR, CALR1, CRT, HEL-S-99n, RO, SSA, cC1qR
Name
(RefSeq) calreticulin
  KO
K08057  calreticulin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04141  Protein processing in endoplasmic reticulum
hsa04145  Phagosome
hsa04148  Efferocytosis
hsa04612  Antigen processing and presentation
hsa05142  Chagas disease
hsa05163  Human cytomegalovirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05168  Herpes simplex virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05170  Human immunodeficiency virus 1 infection
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus 1 (HIV-1)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06167  Human cytomegalovirus (HCMV)
nt06168  Herpes simplex virus 1 (HSV-1)
nt06220  Calcium signaling (cancer)
nt06229  MHC presentation (cancer)
nt06535  Efferocytosis
nt06537  TCR/BCR signaling
  Element
N00363  Antigen processing and presentation by MHC class I molecules
N00490  HTLV-1 p12 to calcineurin signaling pathway
N01764  Calreticulin-LRP1 mediated recognition and engulfment
Disease
H01605  Myelofibrosis
H01612  Essential thrombocythemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    811 (CALR)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    811 (CALR)
   04148 Efferocytosis
    811 (CALR)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    811 (CALR)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    811 (CALR)
   05170 Human immunodeficiency virus 1 infection
    811 (CALR)
   05168 Herpes simplex virus 1 infection
    811 (CALR)
   05163 Human cytomegalovirus infection
    811 (CALR)
   05169 Epstein-Barr virus infection
    811 (CALR)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    811 (CALR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    811 (CALR)
  09183 Protein families: signaling and cellular processes
   04091 Lectins [BR:hsa04091]
    811 (CALR)
Chaperones and folding catalysts [BR:hsa03110]
 Other chaperones and cochaperones
  Calnexin / calreticulin
   811 (CALR)
Lectins [BR:hsa04091]
 Calnexin / calreticulin
  811 (CALR)
SSDB
Motif
Pfam: Calreticulin
Other DBs
NCBI-GeneID: 811
NCBI-ProteinID: NP_004334
OMIM: 109091
HGNC: 1455
Ensembl: ENSG00000179218
UniProt: P27797 V9HW88
Structure
Position
19:12938609..12944489
AA seq 417 aa
MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDE
EKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQT
DMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDN
TYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPE
HIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYS
PDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDK
QDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgctgctatccgtgccgctgctgctcggcctcctcggcctggccgtcgccgagcctgcc
gtctacttcaaggagcagtttctggacggagacgggtggacttcccgctggatcgaatcc
aaacacaagtcagattttggcaaattcgttctcagttccggcaagttctacggtgacgag
gagaaagataaaggtttgcagacaagccaggatgcacgcttttatgctctgtcggccagt
ttcgagcctttcagcaacaaaggccagacgctggtggtgcagttcacggtgaaacatgag
cagaacatcgactgtgggggcggctatgtgaagctgtttcctaatagtttggaccagaca
gacatgcacggagactcagaatacaacatcatgtttggtcccgacatctgtggccctggc
accaagaaggttcatgtcatcttcaactacaagggcaagaacgtgctgatcaacaaggac
atccgttgcaaggatgatgagtttacacacctgtacacactgattgtgcggccagacaac
acctatgaggtgaagattgacaacagccaggtggagtccggctccttggaagacgattgg
gacttcctgccacccaagaagataaaggatcctgatgcttcaaaaccggaagactgggat
gagcgggccaagatcgatgatcccacagactccaagcctgaggactgggacaagcccgag
catatccctgaccctgatgctaagaagcccgaggactgggatgaagagatggacggagag
tgggaacccccagtgattcagaaccctgagtacaagggtgagtggaagccccggcagatc
gacaacccagattacaagggcacttggatccacccagaaattgacaaccccgagtattct
cccgatcccagtatctatgcctatgataactttggcgtgctgggcctggacctctggcag
gtcaagtctggcaccatctttgacaacttcctcatcaccaacgatgaggcatacgctgag
gagtttggcaacgagacgtggggcgtaacaaaggcagcagagaaacaaatgaaggacaaa
caggacgaggagcagaggcttaaggaggaggaagaagacaagaaacgcaaagaggaggag
gaggcagaggacaaggaggatgatgaggacaaagatgaggatgaggaggatgaggaggac
aaggaggaagatgaggaggaagatgtccccggccaggccaaggacgagctgtag

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