KEGG   Homo sapiens (human): 8140
Entry
8140              CDS       T01001                                 
Symbol
SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16
Name
(RefSeq) solute carrier family 7 member 5
  KO
K13780  solute carrier family 7 (L-type amino acid transporter), member 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04150  mTOR signaling pathway
hsa05230  Central carbon metabolism in cancer
Network
nt06522  mTOR signaling
  Element
N01584  FLCN-mTORC1 signaling pathway
Drug target
Nanvuranlat hydrochloride hydrate: D12443
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    8140 (SLC7A5)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    8140 (SLC7A5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hsa02000]
    8140 (SLC7A5)
Transporters [BR:hsa02000]
 Solute carrier family (SLC)
  SLC7: Cationic amino acid transporter/glycoprotein-associated
   8140 (SLC7A5)
SSDB
Motif
Pfam: AA_permease_2 AA_permease
Other DBs
NCBI-GeneID: 8140
NCBI-ProteinID: NP_003477
OMIM: 600182
HGNC: 11063
Ensembl: ENSG00000103257
UniProt: Q01650
Structure
Position
16:complement(87830023..87869507)
AA seq 507 aa
MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
NT seq 1524 nt   +upstreamnt  +downstreamnt
atggcgggtgcgggcccgaagcggcgcgcgctagcggcgccggcggccgaggagaaggaa
gaggcgcgggagaagatgctggccgccaagagcgcggacggctcggcgccggcaggcgag
ggcgagggcgtgaccctgcagcggaacatcacgctgctcaacggcgtggccatcatcgtg
gggaccattatcggctcgggcatcttcgtgacgcccacgggcgtgctcaaggaggcaggc
tcgccggggctggcgctggtggtgtgggccgcgtgcggcgtcttctccatcgtgggcgcg
ctctgctacgcggagctcggcaccaccatctccaaatcgggcggcgactacgcctacatg
ctggaggtctacggctcgctgcccgccttcctcaagctctggatcgagctgctcatcatc
cggccttcatcgcagtacatcgtggccctggtcttcgccacctacctgctcaagccgctc
ttccccacctgcccggtgcccgaggaggcagccaagctcgtggcctgcctctgcgtgctg
ctgctcacggccgtgaactgctacagcgtgaaggccgccacccgggtccaggatgccttt
gccgccgccaagctcctggccctggccctgatcatcctgctgggcttcgtccagatcggg
aagggtgatgtgtccaatctagatcccaacttctcatttgaaggcaccaaactggatgtg
gggaacattgtgctggcattatacagcggcctctttgcctatggaggatggaattacttg
aatttcgtcacagaggaaatgatcaacccctacagaaacctgcccctggccatcatcatc
tccctgcccatcgtgacgctggtgtacgtgctgaccaacctggcctacttcaccaccctg
tccaccgagcagatgctgtcgtccgaggccgtggccgtggacttcgggaactatcacctg
ggcgtcatgtcctggatcatccccgtcttcgtgggcctgtcctgcttcggctccgtcaat
gggtccctgttcacatcctccaggctcttcttcgtggggtcccgggaaggccacctgccc
tccatcctctccatgatccacccacagctcctcacccccgtgccgtccctcgtgttcacg
tgtgtgatgacgctgctctacgccttctccaaggacatcttctccgtcatcaacttcttc
agcttcttcaactggctctgcgtggccctggccatcatcggcatgatctggctgcgccac
agaaagcctgagcttgagcggcccatcaaggtgaacctggccctgcctgtgttcttcatc
ctggcctgcctcttcctgatcgccgtctccttctggaagacacccgtggagtgtggcatc
ggcttcaccatcatcctcagcgggctgcccgtctacttcttcggggtctggtggaaaaac
aagcccaagtggctcctccagggcatcttctccacgaccgtcctgtgtcagaagctcatg
caggtggtcccccaggagacatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
3D Structure (7)   
   PDB (7)   
Protein domain (2)   
   Pfam (2)   
All databases (63)   

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