KEGG   Homo sapiens (human): 8202
Entry
8202              CDS       T01001                                 
Symbol
NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Name
(RefSeq) nuclear receptor coactivator 3
  KO
K11256  nuclear receptor coactivator 3 [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    8202 (NCOA3)
   04919 Thyroid hormone signaling pathway
    8202 (NCOA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8202 (NCOA3)
  09162 Cancer: specific types
   05224 Breast cancer
    8202 (NCOA3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    8202 (NCOA3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8202 (NCOA3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     8202 (NCOA3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    8202 (NCOA3)
SSDB
Motif
Pfam: NCOA_u2 DUF4927 SRC-1 Nuc_rec_co-act PAS_11 DUF1518 PAS PAS_3 PAS_9 HLH PAS_4 Per3-like_PAS-A TERB2
Other DBs
NCBI-GeneID: 8202
NCBI-ProteinID: NP_858045
OMIM: 601937
HGNC: 7670
Ensembl: ENSG00000124151
UniProt: Q9Y6Q9
Structure
Position
20:47501887..47656872
AA seq 1424 aa
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
GGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ
FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
NT seq 4275 nt   +upstreamnt  +downstreamnt
atgagtggattaggagaaaacttggatccactggccagtgattcacgaaaacgcaaattg
ccatgtgatactccaggacaaggtcttacctgcagtggtgaaaaacggagacgggagcag
gaaagtaaatatattgaagaattggctgagctgatatctgccaatcttagtgatattgac
aatttcaatgtcaaaccagataaatgtgcgattttaaaggaaacagtaagacagatacgt
caaataaaagagcaaggaaaaactatttccaatgatgatgatgttcaaaaagccgatgta
tcttctacagggcagggagttattgataaagactccttaggaccgcttttacttcaggca
ttggatggtttcctatttgtggtgaatcgagacggaaacattgtatttgtatcagaaaat
gtcacacaatacctgcaatataagcaagaggacctggttaacacaagtgtttacaatatc
ttacatgaagaagacagaaaggattttcttaagaatttaccaaaatctacagttaatgga
gtttcctggacaaatgagacccaaagacaaaaaagccatacatttaattgccgtatgttg
atgaaaacaccacatgatattctggaagacataaacgccagtcctgaaatgcgccagaga
tatgaaacaatgcagtgctttgccctgtctcagccacgagctatgatggaggaaggggaa
gatttgcaatcttgtatgatctgtgtggcacgccgcattactacaggagaaagaacattt
ccatcaaaccctgagagctttattaccagacatgatctttcaggaaaggttgtcaatata
gatacaaattcactgagatcctccatgaggcctggctttgaagatataatccgaaggtgt
attcagagattttttagtctaaatgatgggcagtcatggtcccagaaacgtcactatcaa
gaagcttatcttaatggccatgcagaaaccccagtatatcgattctcgttggctgatgga
actatagtgactgcacagacaaaaagcaaactcttccgaaatcctgtaacaaatgatcga
catggctttgtctcaacccacttccttcagagagaacagaatggatatagaccaaaccca
aatcctgttggacaagggattagaccacctatggctggatgcaacagttcggtaggcggc
atgagtatgtcgccaaaccaaggcttacagatgccgagcagcagggcctatggcttggca
gaccctagcaccacagggcagatgagtggagctaggtatgggggttccagtaacatagct
tcattgacccctgggccaggcatgcaatcaccatcttcctaccagaacaacaactatggg
ctcaacatgagtagccccccacatgggagtcctggtcttgccccaaaccagcagaatatc
atgatttctcctcgtaatcgtgggagtccaaagatagcctcacatcagttttctcctgtt
gcaggtgtgcactctcccatggcatcttctggcaatactgggaaccacagcttttccagc
agctctctcagtgccctgcaagccatcagtgaaggtgtggggacttcccttttatctact
ctgtcatcaccaggccccaaattggataactctcccaatatgaatattacccaaccaagt
aaagtaagcaatcaggattccaagagtcctctgggcttttattgcgaccaaaatccagtg
gagagttcaatgtgtcagtcaaatagcagagatcacctcagtgacaaagaaagtaaggag
agcagtgttgagggggcagagaatcaaaggggtcctttggaaagcaaaggtcataaaaaa
ttactgcagttacttacctgttcttctgatgaccggggtcattcctccttgaccaactcc
cccctagattcaagttgtaaagaatcttctgttagtgtcaccagcccctctggagtctcc
tcctctacatctggaggagtatcctctacatccaatatgcatgggtcactgttacaagag
aagcaccggattttgcacaagttgctgcagaatgggaattcaccagctgaggtagccaag
attactgcagaagccactgggaaagacaccagcagtataacttcttgtggggacggaaat
gttgtcaagcaggagcagctaagtcctaagaagaaggagaataatgcacttcttagatac
ctgctggacagggatgatcctagtgatgcactctctaaagaactacagccccaagtggaa
ggagtggataataaaatgagtcagtgcaccagctccaccattcctagctcaagtcaagag
aaagaccctaaaattaagacagagacaagtgaagagggatctggagacttggataatcta
gatgctattcttggtgatctgactagttctgacttttacaataattccatatcctcaaat
ggtagtcatctggggactaagcaacaggtgtttcaaggaactaattctctgggtttgaaa
agttcacagtctgtgcagtctattcgtcctccatataaccgagcagtgtctctggatagc
cctgtttctgttggctcaagtcctccagtaaaaaatatcagtgctttccccatgttacca
aagcaacccatgttgggtgggaatccaagaatgatggatagtcaggaaaattatggctca
agtatgggtgggccaaaccgaaatgtgactgtgactcagactccttcctcaggagactgg
ggcttaccaaactcaaaggccggcagaatggaacctatgaattcaaactccatgggaaga
ccaggaggagattataatacttctttacccagacctgcactgggtggctctattcccaca
ttgcctcttcggtctaatagcataccaggtgcgagaccagtattgcaacagcagcagcag
atgcttcaaatgaggcctggtgaaatccccatgggaatgggggctaatccctatggccaa
gcagcagcatctaaccaactgggttcctggcccgatggcatgttgtccatggaacaagtt
tctcatggcactcaaaataggcctcttcttaggaattccctggatgatcttgttgggcca
ccttccaacctggaaggccagagtgacgaaagagcattattggaccagctgcacactctt
ctcagcaacacagatgccacaggcctggaagaaattgacagagctttgggcattcctgaa
cttgtcaatcagggacaggcattagagcccaaacaggatgctttccaaggccaagaagca
gcagtaatgatggatcagaaggcaggattatatggacagacatacccagcacaggggcct
ccaatgcaaggaggctttcatcttcagggacaatcaccatcttttaactctatgatgaat
cagatgaaccagcaaggcaattttcctctccaaggaatgcacccacgagccaacatcatg
agaccccggacaaacacccccaagcaacttagaatgcagcttcagcagaggctgcagggc
cagcagtttttgaatcagagccgacaggcacttgaattgaaaatggaaaaccctactgct
ggtggtgctgcggtgatgaggcctatgatgcagccccaggtgagctcccagcagggtttt
cttaatgctcaaatggtcgcccaacgcagcagagagctgctaagtcatcacttccgacaa
cagagggtggctatgatgatgcagcagcagcagcagcagcaacagcagcagcagcagcag
cagcagcagcaacagcaacagcaacagcaacagcagcaacagcagcaaacccaggccttc
agcccacctcctaatgtgactgcttcccccagcatggatgggcttttggcaggacccaca
atgccacaagctcctccgcaacagtttccatatcaaccaaattatggaatgggacaacaa
ccagatccagcctttggtcgagtgtctagtcctcccaatgcaatgatgtcgtcaagaatg
ggtccctcccagaatcccatgatgcaacacccgcaggctgcatccatctatcagtcctca
gaaatgaagggctggccatcaggaaatttggccaggaacagctccttttcccagcagcag
tttgcccaccaggggaatcctgcagtgtatagtatggtgcacatgaatggcagcagtggt
cacatgggacagatgaacatgaaccccatgcccatgtctggcatgcctatgggtcctgat
cagaaatactgctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (5)   
   KEGG NETWORK (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (38)   
   RefSeq(nuc) (4)   
   GenBank (17)   
   EMBL (17)   
3D Structure (5)   
   PDB (5)   
Protein domain (13)   
   Pfam (13)   
All databases (97)   

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