KEGG   Homo sapiens (human): 825
Entry
825               CDS       T01001                                 
Symbol
CAPN3, CANP3, CANPL3, LGMD2, LGMD2A, LGMDD4, LGMDR1, nCL-1, p94
Name
(RefSeq) calpain 3
  KO
K08573  calpain-3 [EC:3.4.22.54]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04820  Cytoskeleton in muscle cells
Disease
H00592  Calpainopathy
H00593  Limb-girdle muscular dystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    825 (CAPN3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    825 (CAPN3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.54  calpain-3
     825 (CAPN3)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C2: calpain family
   825 (CAPN3)
SSDB
Motif
Pfam: Peptidase_C2 Calpain_III Calpain_u2 EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_8 EF-hand_5
Other DBs
NCBI-GeneID: 825
NCBI-ProteinID: NP_000061
OMIM: 114240
HGNC: 1480
Ensembl: ENSG00000092529
UniProt: P20807
Structure
Position
15:42359501..42412317
AA seq 821 aa
MPTVISASVAPRTAAEPRSPGPVPHPAQSKATEAGGGNPSGIYSAIISRNFPIIGVKEKT
FEQLHKKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIDGANRTD
ICQGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHFQFWRYGEWVDVVIDD
CLPTYNNQLVFTKSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVAEFFE
IRDAPSDMYKIMKKAIERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLQ
DSDLDPRGSDERPTRTIIPVQYETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRLRNPW
GQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADA
LQSDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSF
LVALMQKNRRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINM
REVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVKKKKTK
PIIFVSDRANSNKELGVDQESEEGKGKTSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQ
IAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHL
WNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFD
SFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
NT seq 2466 nt   +upstreamnt  +downstreamnt
atgccgaccgtcattagcgcatctgtggctccaaggacagcggctgagccccggtcccca
gggccagttcctcacccggcccagagcaaggccactgaggctgggggtggaaacccaagt
ggcatctattcagccatcatcagccgcaattttcctattatcggagtgaaagagaagaca
ttcgagcaacttcacaagaaatgtctagaaaagaaagttctttatgtggaccctgagttc
ccaccggatgagacctctctcttttatagccagaagttccccatccagttcgtctggaag
agacctccggaaatttgcgagaatccccgatttatcattgatggagccaacagaactgac
atctgtcaaggagagctaggggactgctggtttctcgcagccattgcctgcctgaccctg
aaccagcaccttcttttccgagtcataccccatgatcaaagtttcatcgaaaactacgca
gggatcttccacttccagttctggcgctatggagagtgggtggacgtggttatagatgac
tgcctgccaacgtacaacaatcaactggttttcaccaagtccaaccaccgcaatgagttc
tggagtgctctgctggagaaggcttatgctaagctccatggttcctacgaagctctgaaa
ggtgggaacaccacagaggccatggaggacttcacaggaggggtggcagagttttttgag
atcagggatgctcctagtgacatgtacaagatcatgaagaaagccatcgagagaggctcc
ctcatgggctgctccattgatgatggcacgaacatgacctatggaacctctccttctggt
ctgaacatgggggagttgattgcacggatggtaaggaatatggataactcactgctccag
gactcagacctcgaccccagaggctcagatgaaagaccgacccggacaatcattccggtt
cagtatgagacaagaatggcctgcgggctggtcagaggtcacgcctactctgtcacgggg
ctggatgaggtcccgttcaaaggtgagaaagtgaagctggtgcggctgcggaatccgtgg
ggccaggtggagtggaacggttcttggagtgatagatggaaggactggagctttgtggac
aaagatgagaaggcccgtctgcagcaccaggtcactgaggatggagagttctggatgtcc
tatgaggatttcatctaccatttcacaaagttggagatctgcaacctcacggccgatgct
ctgcagtctgacaagcttcagacctggacagtgtctgtgaacgagggccgctgggtacgg
ggttgctctgccggaggctgccgcaacttcccagatactttctggaccaaccctcagtac
cgtctgaagctcctggaggaggacgatgaccctgatgactcggaggtgatttgcagcttc
ctggtggccctgatgcagaagaaccggcggaaggaccggaagctaggggccagtctcttc
accattggcttcgccatctacgaggttcccaaagagatgcacgggaacaagcagcacctg
cagaaggacttcttcctgtacaacgcctccaaggccaggagcaaaacctacatcaacatg
cgggaggtgtcccagcgcttccgcctgcctcccagcgagtacgtcatcgtgccctccacc
tacgagccccaccaggagggggaattcatcctccgggtcttctctgaaaagaggaacctc
tctgaggaagttgaaaataccatctccgtggatcggccagtgaaaaagaaaaaaaccaag
cccatcatcttcgtttcggacagagcaaacagcaacaaggagctgggtgtggaccaggag
tcagaggagggcaaaggcaaaacaagccctgataagcaaaagcagtccccacagccacag
cctggcagctctgatcaggaaagtgaggaacagcaacaattccggaacattttcaagcag
atagcaggagatgacatggagatctgtgcagatgagctcaagaaggtccttaacacagtc
gtgaacaaacacaaggacctgaagacacacgggttcacactggagtcctgccgtagcatg
attgcgctcatggatacagatggctctggaaagctcaacctgcaggagttccaccacctc
tggaacaagattaaggcctggcagaaaattttcaaacactatgacacagaccagtccggc
accatcaacagctacgagatgcgaaatgcagtcaacgacgcaggattccacctcaacaac
cagctctatgacatcattaccatgcggtacgcagacaaacacatgaacatcgactttgac
agtttcatctgctgcttcgttaggctggagggcatgttcagagcttttcatgcatttgac
aaggatggagatggtatcatcaagctcaacgttctggagtggctgcagctcaccatgtat
gcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (59)   
   RefSeq(nuc) (9)   
   GenBank (25)   
   EMBL (25)   
3D Structure (5)   
   PDB (5)   
Protein domain (8)   
   Pfam (8)   
All databases (116)   

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