KEGG   Homo sapiens (human): 8277
Entry
8277              CDS       T01001                                 
Symbol
TKTL1, TKR, TKT2
Name
(RefSeq) transketolase like 1
  KO
K00615  transketolase [EC:2.2.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00030  Pentose phosphate pathway
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01230  Biosynthesis of amino acids
Module
hsa_M00004  Pentose phosphate pathway (Pentose phosphate cycle)
hsa_M00007  Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00030 Pentose phosphate pathway
    8277 (TKTL1)
  09109 Metabolism of terpenoids and polyketides
   01051 Biosynthesis of ansamycins
    8277 (TKTL1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.1  transketolase
     8277 (TKTL1)
SSDB
Motif
Pfam: Transket_pyr Transketolase_C Transketolase_N E1_dh DXP_synthase_N
Other DBs
NCBI-GeneID: 8277
NCBI-ProteinID: NP_036385
OMIM: 300044
HGNC: 11835
Ensembl: ENSG00000007350
UniProt: P51854
Position
X:154295795..154330350
AA seq 596 aa
MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL
FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV
FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF
GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER
ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA
KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA
STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF
YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI
GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG
GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
NT seq 1791 nt   +upstreamnt  +downstreamnt
atggcggatgctgaggcgagggctgagttcccggaggaggccagacctgacaggggcacc
ttgcaggtgttgcaagatatggccagccgcttgcgaatccattccatcagggccacatgc
tccacgagctccggccaccctacatcatgtagcagttcttctgagatcatgtctgtgctg
ttcttctacatcatgaggtacaagcagtcagatccagagaatccggacaacgaccgattt
gtcctcgcaaagagactgtcgtttgtggatgtggcaacaggatggctcggacaaggactg
ggagttgcatgtggaatggcatatactggcaagtacttcgacagggccagctaccgggtg
ttctgcctcatgagtgatggcgagtcctcagaaggctctgtctgggaggcaatggccttt
gcttcctactacagtctggacaatcttgtggcaatctttgatgtgaaccgcctgggacac
agtggtgcattgcccgccgagcactgcataaacatctatcagaggcgctgcgaagccttt
gggtggaacacttatgtggtggacggccgggacgtggaggcactgtgccaggtattctgg
caggcttctcaggtgaagcacaagcccactgctgtggtggccaagaccttcaagggccgg
ggcaccccaagtattgaggatgcagaaagttggcatgcaaagccaatgccgagagaaaga
gcagatgccattatcaaattaattgagagccagatacagaccagcaggaatcttgaccca
cagccccccattgaggactcacctgaagtcaacatcacagatgtaaggatgacctctcca
cctgattacagagttggtgacaagatagctactcggaaagcatgcggtctggctctggct
aagctgggctacgcgaacaacagagtcgttgtgctggatggtgacaccaggtactctact
ttctctgagatattcaacaaggagtaccctgagcgcttcatcgagtgctttatggctgaa
caaaacatggtgagcgtggctctgggctgtgcctcccgtggacggaccattgcttttgct
agcacctttgctgcctttctgactcgagcatttgatcacatccggataggaggcctcgct
gagagcaacatcaacattattggttcccactgtggggtatctgttggtgacgatggtgct
tcccagatggccctggaggatatagccatgttccgaaccattcccaagtgcacgatcttc
tacccaactgatgccgtctccacggagcatgctgttgctctggcagccaatgccaagggg
atgtgcttcattcggaccacccgaccagaaactatggttatttacaccccacaagaacgc
tttgagatcggacaggccaaggtcctccgccactgtgtcagtgacaaggtcacagttatt
ggagctggaattactgtgtatgaagccttagcagctgctgatgagctttcgaaacaagat
atttttatccgtgtcatcgacctgtttaccattaaacctctggatgtcgccaccatcgtc
tccagtgcaaaagccacagagggccggatcattacagtggaggatcactacccgcaaggt
ggcatcggggaagctgtctgcgcagccgtctccatggatcctgacattcaggttcattcg
ctggcagtgtcgggagtgccccagagtgggaagtccgaggaattgctggatatgtatgga
attagtgccagacatatcatagtggccgtgaaatgcatgttgctgaactaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (4)   
   KEGG MODULE (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (25)   
   RefSeq(nuc) (3)   
   GenBank (11)   
   EMBL (11)   
Protein domain (5)   
   Pfam (5)   
All databases (72)   

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