KEGG   Homo sapiens (human): 8287
Entry
8287              CDS       T01001                                 
Symbol
USP9Y, DFFRY, SPGFY2
Name
(RefSeq) ubiquitin specific peptidase 9 Y-linked
  KO
K11840  ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
Organism
hsa  Homo sapiens (human)
Disease
H00890  Azoospermia
H02534  Y-linked spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    8287 (USP9Y)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8287 (USP9Y)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.19  Omega peptidases
    3.4.19.12  ubiquitinyl hydrolase 1
     8287 (USP9Y)
Peptidases and inhibitors [BR:hsa01002]
 Cysteine peptidases
  Family C19: ubiquitin-specific protease family
   8287 (USP9Y)
Ubiquitin system [BR:hsa04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    8287 (USP9Y)
SSDB
Motif
Pfam: DUF3517 UCH UCH_1 Dsc3_N
Other DBs
NCBI-GeneID: 8287
NCBI-ProteinID: NP_004645
OMIM: 400005
HGNC: 12633
Ensembl: ENSG00000114374
UniProt: O00507
Position
Y:12701231..12860839
AA seq 2555 aa
MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ
HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF
FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN
PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD
RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK
NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN
KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF
VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA
SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS
CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR
HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN
FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF
FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI
QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS
INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV
DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS
LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS
FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL
FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT
DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ
SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS
PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID
LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL
LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL
AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI
NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG
LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF
GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV
NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT
TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK
RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA
GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN
QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIARPH
QIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEE
ITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR
FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRA
TLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIK
YQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDIL
FVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDL
LFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCP
VAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLER
SHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT
GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ
NT seq 7668 nt   +upstreamnt  +downstreamnt
atgacagccatcactcatggctctccagtaggagggaacgacagccagggccaggttctt
gatggccagtctcagcatctcttccaacagaaccagacttcatcacctgattcttccaat
gagaattccgtagcaactcctcctccagaggaacaagggcaaggtgatgccccaccacag
catgaagatgaagagcctgcatttccacatactgagctggcaaacctggatgacatgatc
aacaggcctcgatgggtggttcctgttttgccaaaaggggaattagaagtgcttttagaa
gctgctattgatcttagtgtaaaaggccttgatgttaaaagtgaagcatgccaacgtttt
tttcgagatggactaacaatatctttcactaaaattcttatggatgaggctgtgagtggc
tggaagtttgaaattcatagatgtattattaacaatactcatcgcctagtggagctttgt
gtggccaagttgtcccaagattggtttccacttctagaacttctcgccatggccttaaat
cctcactgcaagtttcatatctacaatggtacacgtccgtgtgaattaatttcctcaaat
gctcagttgcctgaagatgaattatttgctcgttcttcagatcctcgatcaccaaaaggt
tggctagtggatctcatcaataaatttggcacattaaatgggttccagattttgcatgat
cgtttttttaatggatcagcattaaatattcaaataattgcagctcttattaaaccattt
ggacaatgctatgagtttctcagtcaacatacactgaaaaagtacttcattccagttata
gaaatagttccacatttattggaaaacttaactgatgaagaactgaaaaaggaggcaaag
aatgaagccaaaaatgatgccctttcaatgattattaaatctttgaagaacttagcttca
agaatttcaggacaagatgagactataaaaaatttggaaatttttaggttaaagatgata
ctcagattgttgcaaatttcctcttttaatggaaagatgaatgcactgaatgaaataaat
aaggttatatctagtgtatcatattatactcatcggcatagtaatcctgaggaggaagaa
tggctgacagctgagcgaatggcagaatggatacagcaaaataatatcttatccatagtc
ttgcaagacagtcttcatcaaccacaatatgtagaaaagctagagaaaattcttcgtttt
gtgattaaagaaaaggctcttacattacaggaccttgataatatctgggcagcacaggca
ggaaaacatgaagccattgtgaagaatgtacatgatctgctagcaaagttggcttgggat
ttttctcctggacaacttgatcatctttttgattgctttaaggcaagttggacaaatgca
agtaaaaagcaacgtgaaaagctccttgagttgatacgccgtcttgcagaagatgataaa
gatggtgtgatggcacacaaagtgttgaaccttctttggaacctggctcagagtgatgat
gtgcctgtagacatcatggaccttgctcttagtgcccacataaaaatactagattatagt
tgttcccaggatcgagatgcacagaagatccagtggatagatcactttatagaagaactt
cgcacaaatgacaagtgggtaattcctgctctgaaacaaataagagaaatttgtagtttg
tttggtgaagcatctcaaaatttgagtcaaactcagcgaagtccccacatattttatcgc
catgatttaatcaaccagcttcaacaaaatcatgctttagttactttggtagcagaaaac
cttgcaacctacatgaatagcatcagattgtatgctggagatcatgaagactatgatcca
caaacagtgaggcttggaagtcgatacagtcatgttcaagaagttcaagaacgactaaac
ttccttagatttttactgaaggatggccaactgtggctctgtgctcctcaggcaaaacaa
atatggaagtgcttagcagaaaatgcagtttatctttgtgatcgtgaagcctgttttaag
tggtattccaagttaatgggggatgaaccagacttggatcctgatattaataaggacttc
tttgaaagtaatgtacttcagcttgatccttcccttttaactgaaaatggaatgaaatgc
tttgaaagatttttcaaagctgtcaattgtcgagaaaggaaactaatagcaaaaagaaga
tcctatatgatggatgatttggaattaattggactagactacctttggagggttgtgatt
cagagtagtgacgagattgctaacagagctatagatcttcttaaagagatatacacaaac
cttggcccaagattaaaagccaatcaggtggttatccatgaagacttcattcagtcttgc
tttgatcgtttaaaagcatcatatgatacactgtgtgtttttgatggtgacaaaaacagc
attaattgtgcaagacaagaagccattcgaatggttagagtattaactgttataaaagag
tacattaatgaatgtgacagtgattatcacaaggaaagaatgattctacctatgtcgaga
gcatttcgtggcaaacacctctctcttatagttcggtttccaaaccagggcagacaggtt
gatgagttggatatatggtctcatacgaatgacacaattggttcagtacggcgatgtatt
gttaatcgtattaaagccaatgtagcccacaaaaaaattgaactttttgtgggtggtgag
ctgatagattctgaagatgacagaaagctaattggacaattaaacttaaaagataaatct
ctaattacagccaaacttacacaaataaatttcaatatgccatcaagtcctgatagctct
tccgattcctcaactgcatctcctggaaaccaccgtaatcattacaatgatggtcccaat
ctagaggtggaaagttgtttgcctggggtgataatgtcagtgcatcccagatacatctct
ttcctttggcaagttgcagacttaggtagcaacctgaatatgccacctcttagagatgga
gcaagagtacttatgaaacttatgccaccagatagaacagctgtagaaaaattacgagct
gtttgtttggaccatgcaaaacttggagaaggcaaacttagtccaccccttgactctctt
ttctttggtccttctgcctcccaagttctatacctaacagaggtagtttatgccttgtta
atgcctgctggtgtgcctctaactgatgggtcctctgactttcaagttcacttcttgaaa
agtggtggcttacctcttgtactgagtatgctaataagaaataacttcttgccaaataca
gatatggaaactcgaaggggtgcttatttaaatgctcttaaaatagccaaactgttgtta
actgcgattggctatggccatgttcgagctgtagcagaagcttgtcagccagttgtagat
ggtacagaccccataacacagattaaccaagttactcatgatcaagcagtggtgctacaa
agtgcccttcagagcattcctaatccctcatccgagtgcgtacttagaaatgagtccata
cttcttgctcaggaaatatctaatgaggcttcaagatatatgcctgatatttgtgtaatt
agggctatacagaaaattatctgggcatcagcatgtggggcattaggactagtttttagc
ccaaatgaagaaataactaaaatttatcagatgaccaccaatggaagcaataagctggag
gtggaagatgaacaagtttgctgtgaagcactggaagtgatgaccttatgttttgcttta
cttccaacagcgttggatgcacttagtaaagaaaaagcctggcagaccttcatcattgac
ttattattgcactgtccaagcaaaactgttcgtcagttggcacaggagcagttcttttta
atgtgcaccagatgttgcatgggacacaggcctctgcttttcttcattactttactcttt
accatactggggagcacagcaagagagaagggtaaatattcaggtgattatttcacactt
ttacggcaccttctcaattatgcttacaatggcaatattaacatacccaatgctgaagtt
cttcttgtcagtgaaattgattggctcaaaaggattagggataatgttaaaaacacaggt
gaaacaggtgtcgaagagccaatactggaaggccaccttggggtaacaaaagagttattg
gcctttcaaacttctgagaaaaagtatcactttggttgtgaaaaaggaggtgctaatctc
attaaagaattaattgatgatttcatctttcccgcatccaaagtttacctgcagtattta
agaagtggagaactaccagctgagcaggctattccagtctgtagttcacccgttaccatc
aatgccggttttgagctacttgtagcattagctattggctgtgtgaggaatctcaaacag
atagtagactgtttgactgaaatgtattacatgggcacagcaattactacttgtgaagca
cttactgagtgggaatatctgccccctgttggaccccgcccaccaaaaggatttgtggga
ctcaaaaatgctggtgctacgtgttacatgaactctgtgatccagcagctatacatgatt
ccttctatcaggaacagtattcttgcaattgaaggcacaggtagtgatttacacgatgat
atgttcggggatgagaagcaggacagtgagagtaatgttgatccccgagatgatgtattt
ggatatcctcatcaatttgaagacaagccagcattaagtaagacagaagataggaaagag
tataatattggtgtcctaagacaccttcaggtcatctttggtcatttagctgcttcccaa
ctacaatactatgtacccagaggattttggaaacagttcaggctttggggtgaacctgtt
aatctccgtgaacaacatgatgccttagagttttttaattctttggtggatagtttagat
gaagctttaaaagctttaggacacccggctatactaagtaaagtcctaggaggctccttt
gctgatcagaagatctgccaaggctgcccacataggtatgaatgtgaagaatcttttaca
actttgaatgtggatattagaaatcatcaaaatcttcttgactctttggaacagtatatc
aaaggagatttattggaaggtgcaaatgcatatcattgtgaaaaatgtgataaaaaggtt
gacacagtaaagcgcctgctaattaaaaaattgcctcgggttcttgctatccaactcaaa
cgatttgactatgactgggaaagagaatgtgcaattaaattcaatgattattttgaattt
cctcgagagctggatatgggaccttacacagtagcaggtgttgcaaacctggaaagggat
aatgtaaactcagaaaatgagttgattgaacagaaagagcagtctgacaatgaaactgca
ggaggcacaaagtacagacttgtaggagtgcttgtacacagtggtcaagcaagcggtggg
cattattattcttacatcattcaaaggaatggtaaagatgatcagacagatcactggtat
aaatttgatgatggagatgtaacagaatgcaaaatggatgatgatgaagaaatgaaaaat
cagtgttttggtggagagtacatgggagaagtatttgatcacatgatgaagcgcatgtca
tataggcgacagaagaggtggtggaatgcttacatacttttttatgaacaaatggatatg
atagatgaagatgatgagatgataagatacatatcagagctaactattgcaagaccccat
cagatcattatgtcaccagccattgagagaagtgtacggaaacaaaatgtgaaatttatg
cataaccgattgcaatatagtttagagtattttcagtttgtgaaaaaactgcttacatgt
aatggtgtttatttaaaccctgctccagggcaggattatttgttgcctgaagcagaagaa
attactatgattagtattcagcttgctgctagattcctctttaccactggatttcacacc
aagaaaatagttcgtggtcctgccagtgactggtatgatgcactgtgcgttcttctccgt
cacagcaaaaatgtacgtttttggtttactcataatgtcctttttaatgtatcaaatcgc
ttctctgaataccttctggagtgccctagtgcagaagtgaggggtgcatttgcaaaactt
atagtgtttattgcacacttttccttgcaagatgggtcttgtccttctccttttgcatct
ccaggaccttctagtcaggcatgtgataacttgagcttgagtgaccacttactaagagcc
acactaaatctcttgagaagggaagtttcagagcatggacatcatttacagcaatatttt
aatttgtttgtaatgtatgccaatttaggtgtggcagaaaaaacacagcttctgaaattg
aatgtacctgctacctttatgcttgtgtctttagacgaaggaccaggtcctccaatcaaa
tatcagtatgctgaattaggcaagttatattcagtagtgtctcagctgattcgttgttgc
aatgtgtcatcaacaatgcagtcttcaatcaatggtaatccccctctccccaatcctttc
ggtgaccttaatttatcacagcctataatgccaattcagcagaatgtgttagacatttta
tttgtgagaacaagttatgtgaagaaaattattgaagactgcagtaactcagaggatacc
atcaaattacttcgcttttgctcttgggagaatcctcagttctcatctactgtcctcagc
gaacttctctggcaggttgcatattcatatacctatgaacttcggccatatttagatcta
cttttccaaattttactgattgaggactcctggcagactcacagaattcataatgcactt
aaaggaattccagatgacagagatgggctgttcgatacaatacagcgctcgaagaatcac
tatcaaaaacgagcatatcagtgcataaaatgtatggtagctctatttagcagttgtcct
gttgcttaccagatcttacagggtaacggagatcttaaaagaaaatggacctgggcagtg
gaatggctaggagatgaacttgaaagaagaccatatactggcaatcctcagtatagttac
aacaattggtctcctccagtacaaagcaatgaaacagcaaatggttatttcttagaaaga
tcacatagtgctaggatgacacttgcaaaagcttgtgaactctgtccagaagaggagcca
gatgaccaggatgccccagatgagcatgagccctctccatcagaagatgccccattatat
cctcattcacctgcctctcagtatcaacagaataatcatgtacatggacagccatataca
ggaccagcagcacatcacttgaacaaccctcagaaaacaggccaacgaacacaagaaaat
tatgaaggcaatgaagaagtatcctcacctcagatgaaggatcagtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (57)   
   KEGG ORTHOLOGY (1)   
   RefGene (51)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (19)   
   RefSeq(nuc) (5)   
   GenBank (7)   
   EMBL (7)   
Protein domain (4)   
   Pfam (4)   
All databases (97)   

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