KEGG   Homo sapiens (human): 8318
Entry
8318              CDS       T01001                                 
Symbol
CDC45, CDC45L, CDC45L2, MGORS7, PORC-PI-1
Name
(RefSeq) cell division cycle 45
  KO
K06628  cell division control protein 45
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06509  DNA replication
  Element
N01468  DNA replication licensing
N01470  Pre-IC formation
N01471  Origin unwinding and elongation
N01473  DNA replication termination
N01474  TRAIP-dependent replisome disassembly
Disease
H01889  Meier-Gorlin syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    8318 (CDC45)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    8318 (CDC45)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   Other initiation factors
    8318 (CDC45)
SSDB
Motif
Pfam: CDC45
Other DBs
NCBI-GeneID: 8318
NCBI-ProteinID: NP_003495
OMIM: 603465
HGNC: 1739
Ensembl: ENSG00000093009
UniProt: O75419
Structure
Position
22:19479466..19520612
AA seq 566 aa
MFVSDFRKEFYEVVQSQRVLLFVASDVDALCACKILQALFQCDHVQYTLVPVSGWQELET
AFLEHKEQFHYFILINCGANVDLLDILQPDEDTIFFVCDTHRPVNVVNVYNDTQIKLLIK
QDDDLEVPAYEDIFRDEEEDEEHSGNDSDGSEPSEKRTRLEEEIVEQTMRRRQRREWEAR
RRDILFDYEQYEYHGTSSAMVMFELAWMLSKDLNDMLWWAIVGLTDQWVQDKITQMKYVT
DVGVLQRHVSRHNHRNEDEENTLSVDCTRISFEYDLRLVLYQHWSLHDSLCNTSYTAARF
KLWSVHGQKRLQEFLADMGLPLKQVKQKFQAMDISLKENLREMIEESANKFGMKDMRVQT
FSIHFGFKHKFLASDVVFATMSLMESPEKDGSGTDHFIQALDSLSRSNLDKLYHGLELAK
KQLRATQQTIASCLCTNLVISQGPFLYCSLMEGTPDVMLFSRPASLSLLSKHLLKSFVCS
TKNRRCKLLPLVMAAPLSMEHGTVTVVGIPPETDSSDRKNFFGRAFEKAAESTSSRMLHN
HFDLSVIELKAEDRSKFLDALISLLS
NT seq 1701 nt   +upstreamnt  +downstreamnt
atgttcgtgtccgatttccgcaaagagttctacgaggtggtccagagccagagggtcctt
ctcttcgtggcctcggacgtggatgctctgtgtgcgtgcaagatccttcaggccttgttc
cagtgtgaccacgtgcaatatacgctggttccagtttctgggtggcaagaacttgaaact
gcatttcttgagcataaagaacagtttcattattttattctcataaactgtggagctaat
gtagacctattggatattcttcaacctgatgaagacactatattctttgtgtgtgacacc
cataggccagtcaatgtcgtcaatgtatacaacgatacccagatcaaattactcattaaa
caagatgatgaccttgaagttcccgcctatgaagacatcttcagggatgaagaggaggat
gaagagcattcaggaaatgacagtgatgggtcagagccttctgagaagcgcacacggtta
gaagaggagatagtggagcaaaccatgcggaggaggcagcggcgagagtgggaggcccgg
agaagagacatcctctttgactacgagcagtatgaatatcatgggacatcgtcagccatg
gtgatgtttgagctggcttggatgctgtccaaggacctgaatgacatgctgtggtgggcc
atcgttggactaacagaccagtgggtgcaagacaagatcactcaaatgaaatacgtgact
gatgttggtgtcctgcagcgccacgtttcccgccacaaccaccggaacgaggatgaggag
aacacactctccgtggactgcacacggatctcctttgagtatgacctccgcctggtgctc
taccagcactggtccctccatgacagcctgtgcaacaccagctataccgcagccaggttc
aagctgtggtctgtgcatggacagaagcggctccaggagttccttgcagacatgggtctt
cccctgaagcaggtgaagcagaagttccaggccatggacatctccttgaaggagaatttg
cgggaaatgattgaagagtctgcaaataaatttgggatgaaggacatgcgcgtgcagact
ttcagcattcattttgggttcaagcacaagtttctggccagcgacgtggtctttgccacc
atgtctttgatggagagccccgagaaggatggctcagggacagatcacttcatccaggct
ctggacagcctctccaggagtaacctggacaagctgtaccatggcctggaactcgccaag
aagcagctgcgagccacccagcagaccattgccagctgcctttgcaccaacctcgtcatc
tcccaggggcctttcctgtactgctctctcatggagggcactccagatgtcatgctgttc
tctaggccggcatccctaagcctgctcagcaaacacctgctcaagtcctttgtgtgttcg
acaaagaaccggcgctgcaaactgctgcccctggtgatggctgcccccctgagcatggag
catggcacagtgaccgtggtgggcatccccccagagaccgacagctcggacaggaagaac
ttttttgggagggcgtttgagaaggcagcggaaagcaccagctcccggatgctgcacaac
cattttgacctctcagtaattgagctgaaagctgaggatcggagcaagtttctggacgca
cttatttccctcctgtcctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (6)   
   KEGG NETWORK (6)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (22)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (20)   
DNA sequence (51)   
   RefSeq(nuc) (21)   
   GenBank (15)   
   EMBL (15)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (103)   

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