KEGG   Homo sapiens (human): 83667
Entry
83667             CDS       T01001                                 
Symbol
SESN2, HI95, SES2, SEST2
Name
(RefSeq) sestrin 2
  KO
K20394  sestrin 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04115  p53 signaling pathway
hsa04150  mTOR signaling pathway
hsa04211  Longevity regulating pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    83667 (SESN2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    83667 (SESN2)
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    83667 (SESN2)
SSDB
Motif
Pfam: PA26 CMD
Other DBs
NCBI-GeneID: 83667
NCBI-ProteinID: NP_113647
OMIM: 607767
HGNC: 20746
Ensembl: ENSG00000130766
UniProt: P58004
Structure
Position
1:28259518..28282491
AA seq 480 aa
MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAES
LEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAA
ARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQA
LLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP
PSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPS
ADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGG
QLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERN
LKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgatcgtggcggactccgagtgccgcgcagagctcaaggactacctgcggttcgccccg
ggcggcgtcggcgactcgggccccggagaggagcagagggagagccgggctcggcgaggc
cctcgagggcccagcgccttcatccccgtggaggaggtccttcgggagggggctgagagc
ctcgagcagcacctggggctggaggcactgatgtcctctgggcgagtagacaacctggca
gtggtgatgggcctgcaccctgactactttaccagcttctggcgcctgcactacctgctg
ctgcacacggatggtcccttggccagctcctggcgccactacattgccatcatggctgcc
gcccgccatcagtgttcttacctggtaggctcccacatggccgagtttctgcagactggt
ggtgaccctgagtggctgctgggcctccaccgggcccccgagaagctgcgcaaactcagc
gagatcaacaagttgctggcgcatcggccatggctcatcaccaaggaacacatccaggcc
ttgctgaagaccggcgagcacacttggtccctggccgagctcattcaggctctggtcctg
ctcacccactgccactcgctctcctccttcgtgtttggctgtggcatcctccctgagggg
gatgcagatggcagccctgccccccaggcacctacaccccctagtgaacagagcagcccc
ccaagcagggacccgttgaacaactctgggggctttgagtctgcccgcgacgtggaggcg
ctgatggagcgcatgcagcagctgcaggagagcctgctgcgggatgaggggacgtcccag
gaggagatggagagccgctttgagctggagaagtcagagagcctgctggtgaccccctca
gctgacatcctggagccctctccacacccagacatgctgtgctttgtggaagaccctact
ttcggatatgaggacttcactcggagaggggctcaggcaccccctaccttccgggcccag
gattatacctgggaagaccatggctactcgctgatccagcggctttaccctgagggtggg
cagctgctggatgagaagttccaggcagcctatagcctcacctacaataccatcgccatg
cacagtggtgtggacacctccgtgctccgcagggccatctggaactatatccactgcgtc
tttggcatcagatatgatgactatgattatggggaggtgaaccagctcctggagcggaac
ctcaaggtctatatcaagacagtggcctgctacccagagaagaccacccgaagaatgtac
aacctcttctggaggcacttccgccactcagagaaggtccacgtgaacttgctgctcctg
gaggcgcgcatgcaagccgctctgctgtacgccctccgtgccatcacccgctacatgacc
tga

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (24)   
   RefSeq(nuc) (4)   
   GenBank (10)   
   EMBL (10)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (63)   

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