KEGG   Homo sapiens (human): 8372
Entry
8372              CDS       T01001                                 
Symbol
HYAL3, HYAL-3, LUCA-3, LUCA3
Name
(RefSeq) hyaluronidase 3
  KO
K01197  hyaluronoglucosaminidase [EC:3.2.1.35]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00531  Glycosaminoglycan degradation
hsa01100  Metabolic pathways
hsa04142  Lysosome
Module
hsa_M00076  Dermatan sulfate degradation
hsa_M00077  Chondroitin sulfate degradation
Network
nt06012  Glycosaminoglycan degradation
  Element
N00610  Dermatan sulfate degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    8372 (HYAL3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    8372 (HYAL3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins [BR:hsa02042]
    8372 (HYAL3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    8372 (HYAL3)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    8372 (HYAL3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.35  hyaluronoglucosaminidase
     8372 (HYAL3)
Bacterial toxins [BR:hsa02042]
 Toxins that damage the extracellular matrix
  Hyaluronidases/Collagenases
   8372 (HYAL3)
Glycosaminoglycan binding proteins [BR:hsa00536]
 Heparan sulfate / Heparin
  Enzymes
   8372 (HYAL3)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Enzymes
  8372 (HYAL3)
SSDB
Motif
Pfam: Glyco_hydro_56 EGF_2 Peptidase_M29
Other DBs
NCBI-GeneID: 8372
NCBI-ProteinID: NP_001186958
OMIM: 604038
HGNC: 5322
Ensembl: ENSG00000186792
UniProt: O43820
Position
3:complement(50292832..50299405)
AA seq 417 aa
MTTQLGPALVLGVALCLGCGQPLPQVPERPFSVLWNVPSAHCEARFGVHLPLNALGIIAN
RGQHFHGQNMTIFYKNQLGLYPYFGPRGTAHNGGIPQALPLDRHLALAAYQIHHSLRPGF
AGPAVLDWEEWCPLWAGNWGRRRAYQAASWAWAQQVFPDLDPQEQLYKAYTGFEQAARAL
MEDTLRVAQALRPHGLWGFYHYPACGNGWHSMASNYTGRCHAATLARNTQLHWLWAASSA
LFPSIYLPPRLPPAHHQAFVRHRLEEAFRVALVGHRHPLPVLAYVRLTHRRSGRFLSQDD
LVQSIGVSAALGAAGVVLWGDLSLSSSEEECWHLHDYLVDTLGPYVINVTRAAMACSHQR
CHGHGRCARRDPGQMEAFLHLWPDGSLGDWKSFSCHCYWGWAGPTCQEPRPGPKEAV
NT seq 1254 nt   +upstreamnt  +downstreamnt
atgaccacgcaactgggcccagccctggtgctgggggtggccctgtgcctgggttgtggc
cagcccctaccacaggtccctgaacgccccttctctgtgctgtggaatgtaccctcagca
cactgtgaggcccgctttggtgtgcacctgccactcaatgctctgggcatcatagccaac
cgtggccagcattttcacggtcagaacatgaccattttctacaagaaccaactcggcctc
tatccctactttggacccaggggcacagctcacaatgggggcatcccccaggctttgccc
cttgaccgccacctggcactggctgcctaccagatccaccacagcctgagacctggcttt
gctggcccagcagtgctggattgggaggagtggtgtccactctgggctgggaactggggc
cgccgccgagcttatcaggcagcctcttgggcttgggcacagcaggtattccctgacctg
gaccctcaggagcagctctacaaggcctatactggctttgagcaggcggcccgtgcactg
atggaggatacgctgcgggtggcccaggcactacggccccatggactctggggcttctat
cactacccagcctgtggcaatggctggcatagtatggcttccaactataccggccgctgc
catgcagccacccttgcccgcaacactcaactgcattggctctgggccgcctccagtgcc
ctcttccccagcatctacctcccacccaggctgccacctgcccaccaccaggcctttgtc
cgacatcgcctggaggaggccttccgtgtggcccttgttgggcaccgacatcccctgcct
gtcctggcctatgtccgcctcacacaccggagatctgggaggttcctgtcccaggatgac
cttgtgcagtccattggtgtgagtgcagcactaggggcagccggcgtggtgctctggggg
gacctgagcctctccagctctgaggaggagtgctggcatctccatgactacctggtggac
accttgggcccctatgtgatcaatgtgaccagggcagcgatggcctgcagtcaccagcgg
tgccatggccacgggcgctgtgcccggcgagatccaggacagatggaagcctttctacac
ctgtggccagacggcagccttggagattggaagtccttcagctgccactgttactggggc
tgggctggccccacctgccaggagcccaggcctgggcctaaagaagcagtataa

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (5)   
   GenBank (11)   
   EMBL (11)   
Protein domain (3)   
   Pfam (3)   
All databases (79)   

Download RDF
DBGET integrated database retrieval system