KEGG   Homo sapiens (human): 83746
Entry
83746             CDS       T01001                                 
Symbol
L3MBTL2, H-l(3)mbt-l, L3MBT
Name
(RefSeq) L3MBTL histone methyl-lysine binding protein 2
  KO
K24387  lethal(3)malignant brain tumor-like protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03083  Polycomb repressive complex
Network
nt06506  Double-strand break repair
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01439  Double-strand break signaling
N01614  Activation of PRC2.2 by ubiquitination of H2AK119 in germline genes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    83746 (L3MBTL2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    83746 (L3MBTL2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    83746 (L3MBTL2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys2HisCys zinc factors
    83746 (L3MBTL2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     83746 (L3MBTL2)
SSDB
Motif
Pfam: MBT zf-FCS_1
Other DBs
NCBI-GeneID: 83746
NCBI-ProteinID: NP_113676
OMIM: 611865
HGNC: 18594
Ensembl: ENSG00000100395
UniProt: Q969R5 A0A0S2Z5X6
Structure
Position
22:41205312..41231271
AA seq 705 aa
MEKPRSIEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSVGSESSSYLEESSEAENEDRE
AGELPTSPLHLLSPGTPRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSS
NSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHSQGTGQLADGTPTGQDALVLGFD
WGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIASVIQTAG
YRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKGYLMKR
LVGSRTLPVDFHIKMVESMKYPFRQGMRLEVVDKSQVSRTRMAVVDTVIGGRLRLLYEDG
DSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRSDMAHHPTFRKIYCDAVPYLFKKVRA
VYTEGGWFEEGMKLEAIDPLNLGNICVATVCKVLLDGYLMICVDGGPSTDGLDWFCYHAS
SHAIFPATFCQKNDIELTPPKGYEAQTFNWENYLEKTKSKAAPSRLFNMDCPNHGFKVGM
KLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDSEYDQWVDCESPDIYPVGWCELTGYQ
LQPPVAAEPATPLKAKEATKKKKKQFGKKRKRIPPTKTRPLRQGSKKPLLEDDPQGARKI
SSEPVPGEIIAVRVKEEHLDVASPDKASSPELPVSVENIKQETDD
NT seq 2118 nt   +upstreamnt  +downstreamnt
atggagaagccccggagtattgaggagaccccatcttcagaaccaatggaggaagaggaa
gatgacgacttggagctgtttggtggctatgatagtttccggagttataacagcagtgtg
ggcagtgagagcagctcctatctggaggagtcaagtgaagcagaaaatgaggatcgggaa
gcaggggaactgccgacctccccgctgcatttgctcagccctgggactcctcgctccttg
gatggcagtggttctgagccagctgtctgtgagatgtgtggtatcgtgggtacaagggaa
gccttcttctccaagaccaagaggttctgcagcgtctcctgctccaggagctactcctcc
aactccaagaaagccagtatcttggctaggttacagggaaaaccaccgaccaaaaaagcc
aaagtcctgcacaaggctgcctggtctgccaaaattggagccttcctccactctcaaggg
acaggacagctggcagatgggacaccaacaggacaagacgctctggtcttgggcttcgac
tgggggaagttcctgaaggatcacagttacaaggctgctcccgtcagctgtttcaagcac
gtcccactctatgaccagtgggaggatgtgatgaaagggatgaaggtggaggtgctcaac
agtgatgctgtgctccccagccgggtgtactggatcgcctctgtcatccagacagcaggg
tatcgggtgctgcttcggtatgaaggctttgaaaatgacgccagccatgacttctggtgc
aacctgggaacagtggatgtccaccccattggctggtgtgccatcaacagcaagatccta
gtgcccccacggaccatccatgccaagttcaccgactggaagggctacctcatgaaacgg
ctggtgggctccaggacgcttcccgtggatttccacatcaagatggtggagagcatgaag
tacccctttaggcagggcatgcggctggaagtggtggacaagtcccaggtgtcacgcact
cgcatggctgtggtggacacagtaatcgggggtcgcctacggctcctctacgaggatggt
gacagtgacgacgacttctggtgccacatgtggagccccctgatccacccagtgggttgg
tcacgacgtgtgggccacggcatcaagatgtcagagaggcgaagtgacatggcccatcac
cccaccttccggaagatctactgtgatgccgttccttacctcttcaagaaggtacgagca
gtctacacagaaggcggttggtttgaggaagggatgaagctggaggccattgaccccctg
aatctgggcaacatctgcgtggcaactgtctgtaaggttctcctggatggatacctgatg
atctgtgtggacggggggccctccacagatggcttggactggttctgctaccatgcctct
tcccacgccatcttcccggccaccttctgtcagaagaatgacattgagctcacaccgcca
aaaggttatgaggcacagactttcaactgggagaactacttggagaagaccaagtcgaaa
gccgctccatcgagactctttaacatggattgcccaaaccatggcttcaaggtgggcatg
aagctggaggccgtggacctgatggagccccggctcatctgtgtggccacggtgaaacga
gtggtgcatcggctcctcagcatccactttgacggctgggacagcgagtacgaccagtgg
gtggactgcgagtccccagacatctaccccgtcggctggtgtgagctcaccggctaccag
ctccagcctcctgtggccgcagaaccggccacaccgctgaaggccaaagaggccacaaag
aagaaaaagaaacagtttgggaagaaaaggaaaagaatcccgcccactaagacgcgaccc
ctcagacaggggtccaagaagcccctgctggaggacgaccctcagggtgccaggaagatc
tcgtcggagcctgttcctggcgagatcattgctgtgcgtgtgaaggaagagcatctagac
gtggcctcgcccgacaaggcttcaagtccagagctgcctgtctccgtcgagaacatcaag
caggaaacagacgactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (12)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (36)   
   RefSeq(nuc) (10)   
   GenBank (13)   
   EMBL (13)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (81)   

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