KEGG   Homo sapiens (human): 8379
Entry
8379              CDS       T01001                                 
Symbol
MAD1L1, MAD1, MVA7, PIG9, TP53I9, TXBP181
Name
(RefSeq) mitotic arrest deficient 1 like 1
  KO
K06679  mitotic spindle assembly checkpoint protein MAD1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa05166  Human T-cell leukemia virus 1 infection
hsa05203  Viral carcinogenesis
Network
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle (cancer)
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N00222  HTLV-1 Tax to spindle assembly checkpoint signaling
N00493  Spindle assembly checkpoint signaling
N01529  Recruitment and formation of the MCC
N01532  Kinetochore targeting of MAD1-MAD2
Disease
H00024  Prostate cancer
H01288  Mosaic variegated aneuploidy syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    8379 (MAD1L1)
   04114 Oocyte meiosis
    8379 (MAD1L1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    8379 (MAD1L1)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    8379 (MAD1L1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    8379 (MAD1L1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8379 (MAD1L1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Core SAC proteins
     8379 (MAD1L1)
SSDB
Motif
Pfam: MAD TSC22 Anti-RecBCD_p2
Other DBs
NCBI-GeneID: 8379
NCBI-ProteinID: NP_001013858
OMIM: 602686
HGNC: 6762
Ensembl: ENSG00000002822
UniProt: Q9Y6D9
Structure
Position
7:complement(1815795..2232945)
AA seq 718 aa
MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRS
KSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGA
EEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRV
KRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAA
IVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETL
VGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSAR
GLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDS
ELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKML
KSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRT
KVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKE
VAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPG
DCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA
NT seq 2157 nt   +upstreamnt  +downstreamnt
atggaagacctgggggaaaacaccatggttttatccaccctgagatctttgaacaacttc
atctctcagcgtgtggagggaggctctggactggatatttctacctcggccccaggttct
ctgcagatgcagtaccagcagagcatgcagctggaggaaagagcagagcagatccgttcg
aagtcccacctcatccaggtggagcgggagaaaatgcagatggagctgagtcacaagagg
gctcgagtggagctggagagagcagccagcaccagtgccaggaactacgagcgtgaggtc
gaccgcaaccaggagctcctgacgcgcatccggcagcttcaggagcgggaggccggggcg
gaggagaagatgcaggagcagctggagcgcaacaggcagtgtcagcagaacttggatgct
gccagcaagaggctgcgtgagaaagaggacagtctggcccaggctggcgagaccatcaac
gcactgaaggggaggatctcggaactgcagtggagcgtgatggaccaggagatgcgggtg
aagcgcctggagtcggagaagcaggagctgcaggagcagctggacctgcaacacaaaaaa
tgccaggaagccaatcagaaaatccaggaactccaggccagccaagaagcaagagcagac
cacgagcagcagattaaggatctggagcagaagctgtccctgcaagagcaggatgcagcg
attgtgaagaacatgaagtctgagctggtacggctccctaggctggaacgggagctgaag
cagctgcgggaggagagcgcgcacctgcgggagatgagagagaccaacgggctgctccag
gaagagctggaagggctgcagaggaagctggggcgccaggagaagatgcaggagacgctg
gttggcttggagctggagaacgagaggctgctggccaagctgcaaagctgggagagactg
gaccagaccatgggcctgagcatcaggactccagaagacctttccagattcgtggttgag
ctgcagcagagggagcttgccttgaaggacaagaacagcgccgtcaccagcagcgcccgg
gggctggagaaggccaggcagcagctgcaggaggagctccggcaggtcagcggccagctg
ttggaggagaggaagaagcgcgagacccacgaggcgctggcccggaggctccagaaacgg
gtcctgctgctcaccaaggagcgggacggtatgcgggccatcctggggtcctacgacagc
gagctgaccccggccgagtactcaccccagctgacgcggcgcatgcgggaggctgaggat
atggtgcagaaggtgcacagccacagcgccgagatggaggctcagctgtcgcaggccctg
gaggagctgggaggccagaaacaaagagcagacatgctggagatggagctgaagatgctg
aagtctcagtccagctctgccgaacagagcttcctgttctccagggaggaggcggacacg
ctcaggttgaaggtcgaggagctggaaggcgagcggagtcggctggaggaggaaaagagg
atgctggaggcacagctggagcggcgagctctgcagggtgactatgaccagagcaggacc
aaagtgctgcacatgagcctgaaccccaccagtgtggccaggcagcgcctgcgcgaggac
cacagccagctgcaggcggagtgcgagcgactgcgcgggctcctgcgcgccatggagaga
ggaggcaccgtcccagccgaccttgaggctgccgccgcgagtctgccatcgtccaaggag
gtggcagagctgaagaagcaggtggagagtgccgagctgaagaaccagcggctcaaggag
gttttccagaccaagatccaggagttccgcaaggcctgctacacgctcaccggctaccag
atcgacatcaccacggagaaccagtaccggctgacctcgctgtacgccgagcacccaggc
gactgcctcatcttcaaggccaccagcccctcgggttccaagatgcagctactggagaca
gagttctcacacaccgtgggcgagctcatcgaggtgcacctgcggcgccaggacagcatc
cctgccttcctcagctcgctcaccctcgagctcttcagccgccagaccgtggcgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (7)   
   KEGG NETWORK (7)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (34)   
   RefSeq(nuc) (6)   
   GenBank (14)   
   EMBL (14)   
3D Structure (5)   
   PDB (5)   
Protein domain (3)   
   Pfam (3)   
All databases (96)   

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