KEGG   Homo sapiens (human): 84335
Entry
84335             CDS       T01001                                 
Symbol
AKT1S1, Lobe, PRAS40
Name
(RefSeq) AKT1 substrate 1
  KO
K16184  proline-rich AKT1 substrate 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa04150  mTOR signaling pathway
hsa04152  AMPK signaling pathway
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa04714  Thermogenesis
hsa05131  Shigellosis
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06461  Huntington disease
nt06462  Spinocerebellar ataxia
nt06466  Pathways of neurodegeneration
nt06522  mTOR signaling
nt06532  Autophagy
  Element
N00155  Autophagy-vesicle nucleation/elongation/maturation, mTORC1-PI3KC3-C1
N01575  TSC1/2-mTORC1 signaling pathway
N01578  GATOR1-mTORC1 signaling pathway
N01584  FLCN-mTORC1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    84335 (AKT1S1)
   04150 mTOR signaling pathway
    84335 (AKT1S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    84335 (AKT1S1)
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    84335 (AKT1S1)
   04213 Longevity regulating pathway - multiple species
    84335 (AKT1S1)
  09159 Environmental adaptation
   04714 Thermogenesis
    84335 (AKT1S1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    84335 (AKT1S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    84335 (AKT1S1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    84335 (AKT1S1)
SSDB
Motif
Pfam: PRAS Senescence_reg
Other DBs
NCBI-GeneID: 84335
NCBI-ProteinID: NP_001092102
OMIM: 610221
HGNC: 28426
Ensembl: ENSG00000204673
UniProt: Q96B36
Structure
Position
19:complement(49869033..49878356)
AA seq 256 aa
MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARR
CLHDIALAHRAATAARPPAPPPAPQPPSPTPSPPRPTLAREDNEEDEDEPTETETSGEQL
GISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQY
AKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLP
RPRLNTSDFQKLKRKY
NT seq 771 nt   +upstreamnt  +downstreamnt
atggcgtcggggcgccccgaggagctgtgggaggccgtggtgggggccgctgagcgcttc
cgggcccggactggcacggagctggtgctgctgaccgcggccccgccgccaccaccccgc
ccgggcccctgtgcctatgctgcccatggtcgaggagccctggcggaggcagcgcgccgt
tgcctccacgacatcgcactggcccacagggctgccactgctgctcggcctcctgcgccc
ccaccagcaccacagccacccagtcccacacccagcccaccccggcctaccctggccaga
gaggacaacgaggaggacgaggatgagcccacagagacagagacctccggggagcagctg
ggcattagtgataatggagggctctttgtgatggatgaggacgccaccctccaggacctt
ccccccttctgtgagtcagaccccgagagtacagatgatggcagcctgagcgaggagacc
cccgccggcccccccacctgctcagtgcccccagcctcagccctacccacacagcagtac
gccaagtccctgcctgtgtctgtgcccgtctggggcttcaaggagaagaggacagaggcg
cggtcatcagatgaggagaatgggccgccctcttcgcccgacctggaccgcatcgcggcg
agcatgcgcgcgctggtgctgcgagaggccgaggacacccaggtcttcggggacctgcca
cggccgcggcttaacaccagcgacttccagaagctgaagcggaaatattga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Network (10)   
   KEGG NETWORK (10)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (35)   
   RefSeq(nuc) (5)   
   GenBank (15)   
   EMBL (15)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (91)   

Download RDF
DBGET integrated database retrieval system